Human TREM2 (NP_061838) VersaClone cDNA Summary
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Background: TREM2
The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. The receptors are members of the immunoglobulin superfamily, characterized structurally by a single V-set immunoglobulin (Ig) domain and a short cytoplasmic tail. TREMs associate with the DAP12 signal adapter, an immunoreceptor tyrosine-based activation motif- (ITAM)-containing protein that is phosphorylated and transduces signals when activated.
Citation for Human TREM2 (NP_061838) VersaClone cDNA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
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Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's disease
Authors: LW Bonham, DW Sirkis, J Fan, RE Aparicio, M Tse, EM Ramos, Q Wang, G Coppola, HJ Rosen, BL Miller, JS Yokoyama
Neurocase, 2017-02-01;23(1):65-69. 2017-02-01
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