Human Tyk2 (NP_003322.3) VersaClone cDNA

Catalog #: RDC3610 Datasheet / COA / SDS

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RDC3610

Human Tyk2 (NP_003322.3) VersaClone cDNA

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Human Tyk2 (NP_003322.3) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: Tyk2

Tyk2 belongs to the Janus family of intracellular tyrosine kinases that are activated by receptors for many cytokines. Activation of Tyk2 occurs via phosphorylation at two adjacent tyrosine residues within the kinase domain. Tyk2 is required for interferon-mediated tyrosine phosphorylation of STAT3 and interferon a receptor 1. Mice lacking Tyk2 are susceptible to parasitic infection but resistant to autoimmune arthritis.

Long Name

Protein tyrosine kinase 2

Entrez Gene IDs

7297 (Human); 54721 (Mouse); 298706 (Rat)

Alternate Names

EC 2.7.10; EC 2.7.10.2; JTK1; non-receptor tyrosine-protein kinase TYK2; Tyk2; tyrosine kinase 2