Human UGRP1/SCGB3A2 Antibody

Name: Human UGRP1/SCGB3A2 Antibody
Brand: R&D Systems
SKU: AF3545
Rating: 5 (1 reviews)

Catalog #: AF3545
3 Citations 1 Review Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3545
AF3545-SP

All UGRP1/SCGB3A2 Antibodies

Product Details

Citations (3)

FAQs

Supplemental Products

Reviews (1)

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human UGRP1/SCGB3A2 Antibody Summary

Species Reactivity

Human

Specificity

Detects human UGRP1/SCGB3A2 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant mouse UGRP1 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human UGRP1/SCGB3A2
Phe22-Val93
Accession # Q96PL1

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human UGRP1/SCGB3A2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: UGRP1/SCGB3A2

UGRP-1, also known as secretoglobin family 3A member 2 (SCGB3A2) and High in Normal 2 (HIN-2), is a secreted, 38 kDa, homodimeric protein that is highly expressed in epithelial cells of the airway. UGRP-1 has been shown to bind MARCO (macrophage scavenger receptor with collagenous structure), which is expressed by alveolar macrophages. UGRP1 has been suggested to play a role in lung inflammation. Mature human UGRP1 shares 88% and 81% amino acid sequence identity with rat and mouse mature UGRP1, respectively. Mature UGRP-1 is also 53% identical with that of human mature UGRP-2 (HIN-1).

Long Name

Uteroglobin-related Protein 1

Entrez Gene IDs

117156 (Human); 117158 (Mouse)

Alternate Names

LU103; Pneumo secretory protein 1; PnSP-1; PNSP1secretoglobin family 3A member 2; SCGB3A2; secretoglobin, family 3A, member 2; UGRP1; UGRP1pnSP-1; Uteroglobin-related protein 1

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human UGRP1/SCGB3A2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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Alveolar regeneration by airway secretory-cell-derived p63+ progenitors
Authors: Lv, Z;Liu, Z;Liu, K;Lin, X;Pu, W;Li, Y;Zhao, H;Xi, Y;Sui, P;Vaughan, AE;Gillich, A;Zhou, B;
Cell stem cell
Species: Mouse
Sample Types: Whole Tissue
Applications: Immunohistochemistry
Human distal lung maps and lineage hierarchies reveal a bipotent progenitor
Authors: P Kadur Laks, V Sontake, A Tata, Y Kobayashi, L Macadlo, K Okuda, AS Conchola, S Nakano, S Gregory, LA Miller, JR Spence, JF Engelhardt, RC Boucher, JR Rock, SH Randell, PR Tata
Nature, 2022-03-30;604(7904):111-119.
An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells
Authors: Mart M Lamers, Jelte van der Vaart, Kèvin Knoops, Samra Riesebosch, Tim I Breugem, Anna Z Mykytyn et al.
The EMBO Journal