Human Vasohibin Antibody

Catalog #: MAB33191 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB33191
MAB33191-SP

All Vasohibin Antibodies

Product Details

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Vasohibin Antibody Summary

Species Reactivity

Human

Specificity

Detects human Vasohibin in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG_2B Clone # 411208

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Vasohibin isoform 1
Pro2-Val365
Accession # Q7L8A9

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human Vasohibin

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Vasohibin

Vasohibin is an endothelium-derived negative feedback regulator of angiogenesis. The 365 amino acid (aa), 44 kDa human Vasohibin shows 93% aa identity with mouse Vasohibin. Vasohibin has no canonical signal sequence, but the full-length form is only associated with cells, while N-terminally cleaved, active 42 kDa and 36 kDa forms are both cell-associated and secreted. Minor amounts of C-terminally cleaved 27 kDa form are inactive and lack the C-terminal heparin-binding basic domain. Vasohibin expression is upregulated by VEGF and FGF‑2, but this can be modulated by IL-1, TNF‑ alpha, or IFN‑ gamma.

Entrez Gene IDs

22846 (Human); 238328 (Mouse)

Alternate Names

KIAA1036; KIAA1036vasohibin-1; VASH; VASH1; vasohibin 1; Vasohibin