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Impentamine dihydrobromide

Catalog #: 1858 Datasheet / COA / SDS

Discontinued Product

1858 has been discontinued.
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Impentamine dihydrobromide | CAS No. 149629-70-9 | Histamine H3 Receptor Antagonists
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Description: Selective H3 antagonist
Alternative Names: VUF 4702

Chemical Name: 4-(5-Aminopentyl)imidazole dihydrobromide

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Biological Activity

Impentamine dihydrobromide is a potent and highly selective histamine H3 receptor antagonist (pA2 = 8.4); displays > 30000-fold selectivity over H1 and H2 receptors. Can act as a partial agonist in SK-N-MC cells expressing human H3 receptors. Produces antinociception, possibly via a non-H1, -H2 or -H3 receptor-mediated mechanism, following central administration in vivo.

Technical Data

M.Wt:
315.05
Formula:
C8H15N3.2HBr
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Storage:
Desiccate at RT
CAS No:
149629-70-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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