Isamoltane hemifumarate
Chemical Name: 1-[(1-Methylethyl)amino]-3-[2-(1H-pyrrol-1-yl)]-propan-2-ol hemifumarate
Purity: ≥99%
Biological Activity
Isamoltane hemifumarate is a 5-HT1B antagonist, approximately 30-fold selective over 5-HT1A. Also possesses affinity for β-adrenergic receptors.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Serotonin (5-HT) activation of immortalized hypothalamic neuronal cells through the 5-HT1B serotonin receptor.
Tung S, Hardy A, Wheeler M, Belsham D
Endocrinology, 2012;153(10):4862-73. -
High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain.
Waldmeier et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1988;337:609
Product Datasheets
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Isamoltane hemifumarate
There are currently no reviews for this product. Be the first to review Isamoltane hemifumarate and earn rewards!
Have you used Isamoltane hemifumarate?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
