JIP-1 (153-163)
Biological Activity
Peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.Technical Data
(Modifications: Phe-11 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Identification of the critical features of a small peptide inhibitor of JNK activity.
Barr et al.
J.Biol.Chem., 2002;277:10987
Product Datasheets
Citation for JIP-1 (153-163)
The citations listed below are publications that use Tocris products. Selected citations for JIP-1 (153-163) include:
1 Citation: Showing 1 - 1
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The Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastoma.
Authors: Kumar Et al.
Springerplus 2015;4:19
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