Home / Compounds for Stem Cell Differentiation / KHS 101 hydrochloride

KHS 101 hydrochloride

Catalog #: 4888
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4888/10
4888/50
KHS 101 hydrochloride | CAS No. 1784282-12-7 | Compounds for Stem Cell Differentiation
1 Image
Description: Selective inducer of neuronal differentiation in hippocampal neural progenitors

Chemical Name: N4-(2-Methylpropyl)-N2-[(2-phenyl-4-thiazolyl)methyl]-2,4-pyrimidinediamine hydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

KHS 101 hydrochloride is a selective inducer of neuronal differentiation; induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM). Suppresses astrocyte formation. Also induces acceleration of neuronal differentiation in the hippocampal dentate gyrus in vivo.

Technical Data

M.Wt:
375.92
Formula:
C18H21N5S.HCl
Solubility:
Soluble to 50 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1784282-12-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A small molecule accelerates neuronal differentiation in the adult rat.
    Wurdak et al.
    Proc.Natl.Acad.Sci.USA., 2010;107:16542

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for KHS 101 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for KHS 101 hydrochloride include:

1 Citation: Showing 1 - 1

  1. Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting.
    Authors: Henrik Daa Et al.
    J Exp Clin Cancer Res  2021;40:248

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for KHS 101 hydrochloride

There are currently no reviews for this product. Be the first to review KHS 101 hydrochloride and earn rewards!

Have you used KHS 101 hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.