Home / Glutamate Receptor Compounds / Lamotrigine isethionate

Lamotrigine isethionate

Catalog #: 2289
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2289/10
2289/50
Lamotrigine isethionate | CAS No. 113170-86-8 | Glutamate Receptor Compounds
1 Image
Description: Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)

Chemical Name: 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine isethionate

Purity: ≥99%

Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Lamotrigine isethionate is a water-soluble salt of lamotrigine (Cat. No. 1611). Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.

Technical Data

M.Wt:
382.22
Formula:
C9H7Cl2N5.C2H6O4S
Solubility:
Soluble to 100 mM in water with gentle warming
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
113170-86-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline

Background References

  1. Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture.
    Zona and Avoli
    Epilepsia, 1997;38:522
  2. Cardioprotective effect of lamotr. after focal ischemia in rats.
    Smith and Meldrum
    Stroke, 1995;26:117
  3. Modulation of calcium and potassium currents by lamotr.
    Grunze et al.
    Neuropsychobiology, 1998;38:131
  4. Neurochemical and behavioral aspects of lamotr.
    Leach et al.
    Epilepsia, 1991;32:S4

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for Lamotrigine isethionate

The citations listed below are publications that use Tocris products. Selected citations for Lamotrigine isethionate include:

1 Citation: Showing 1 - 1

  1. Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1.
    Authors: Madry Et al.
    Neuron  2018;97:299

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Lamotrigine isethionate

There are currently no reviews for this product. Be the first to review Lamotrigine isethionate and earn rewards!

Have you used Lamotrigine isethionate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.