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Latanoprost

Catalog #: 4757 Datasheet / COA / SDS

Discontinued Product

4757 has been discontinued.
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Latanoprost | CAS No. 130209-82-4 | Prostanoid Receptor Agonists
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Description: FP prostaglandin receptor agonist; also exhibits agonist activity at EP1 and EP3 receptors

Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptanoic acid 1-methylethyl ester

Purity: ≥97%

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Biological Activity

Latanoprost is a FP prostaglandin receptor agonist; displays greater selectivity than prostanglandin F2α (Cat. No. 4214). Exhibits agonist activity at EP1 and EP3 receptors, but little-to-no effect at EP2, DP, IP and TP prostanoid receptors.

Technical Data

M.Wt:
432.59
Formula:
C26H40O5
Solubility:
Soluble to 50 mM in DMSO and to 50 mM in ethanol
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
130209-82-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. New Human Organotypic Corneal Tissue Model for Ophthalmic Drug Delivery Studies
    Y Kaluzhny, MW Kinuthia, T Truong, AM Lapointe, P Hayden, M Klausner
    Invest. Ophthalmol. Vis. Sci., 2018;59(7):2880-2898.
  2. From PGF2α-isopropyl ester to latanoprost: a review of the development of xalatan: the Proctor Lecture.
    Stjernschantz
    Invest.Ophthalmol.Vis.Sci., 2001;42:1134

Product Datasheets

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