Methyl 2,5-dihydroxycinnamate

Catalog #: 0577 Datasheet / COA / SDS

Discontinued Product

0577 has been discontinued.
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Methyl 2,5-dihydroxycinnamate | CAS No. 63177-57-1 | EGF Receptor Inhibitors
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Description: EGFR-kinase inhibitor
Alternative Names: Erbstatin analog

Purity: ≥98%

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Biological Activity

Methyl 2,5-dihydroxycinnamate is an erbstatin analog. Inhibitor of EGF receptor-associated tyrosine kinases.

Technical Data

M.Wt:
194.19
Formula:
C10H10O4
Solubility:
Soluble to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at RT
CAS No:
63177-57-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors.
    Isshiki et al.
    FEBS Lett., 1990;260:198

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