Home / Additional 5-HT-Related Compounds / Methylergometrine maleate

Methylergometrine maleate

Catalog #: 0549
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
0549/50
0549/250
Methylergometrine maleate | CAS No. 57432-61-8 | Additional 5-HT-Related Compounds
1 Image
Description: Active metabolite of methysergide (Cat. No. 1064)
Alternative Names: Methylergonovine maleate

Chemical Name: [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-6-methylergoline-8-carboxamide maleate

Purity: ≥98%

Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Methylergometrine maleate is an active metabolite of methysergide (Cat. No. 1064); uterotonic agent and oxytocic.

Technical Data

M.Wt:
455.51
Formula:
C20H25N3O2.C4H4O4
Solubility:
Soluble to 25 mM in water
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
57432-61-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Actions of non-peptide ergot alkaloids at 5-HT1-like and 5-HT2 receptors mediating vascular smooth muscle contraction.
    MacLennan and Martin
    Naunyn Schmiedebergs Arch.Pharmacol., 1990;342:120
  3. 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors.
    Pertz
    Naunyn Schmiedebergs Arch.Pharmacol., 1993;348:558
  4. Methylergometrine, an active metabolite of methysergide.
    Muller-Schweinitzer and Tapparelli
    Cephalalgia, 1986;6:35

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Methylergometrine maleate

The citations listed below are publications that use Tocris products. Selected citations for Methylergometrine maleate include:

2 Citations: Showing 1 - 2

  1. Ergot Alkaloids (Re)generate New Leads as Antiparasitics.
    Authors: Chan Et al.
    Cell Signal  2015;9:e0004063
  2. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
    Authors: Murray Et al.
    J Neurophysiol  2011;106:925

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Methylergometrine maleate

There are currently no reviews for this product. Be the first to review Methylergometrine maleate and earn rewards!

Have you used Methylergometrine maleate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.