Metyrapone

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Cholinergic Signals from the CNS Regulate G-CSF-Mediated HSC Mobilization from Bone Marrow via a Glucocorticoid Signaling Relay
   H Pierce, D Zhang, C Magnon, D Lucas, JR Christin, M Huggins, GJ Schwartz, PS Frenette
   Cell Stem Cell, 2017;0(0):.
2. Cytochrome P450-mediated prostaglandin omega/omega-1 hydroxylase activities in porcine ciliary body epithelial cells.
   Asakura and Shichi
   Exp.Eye Res., 1992;55:377
3. Structural and dynamic basis of broad substrate specificity, catalytic mechanism and inhibition of cytochrome P450 3A4.
   Park et al.
   J.Am.Chem.Soc., 2005;127:13634
4. Structure-activity relationship study of the inhibition of adrenal cortical 11β-hydroxylase by new metyr. analogues.
   Hays et al.
   J.Med.Chem., 1984;27:15

Product Datasheets