Miconazole nitrate
Chemical Name: 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate
Purity: ≥99%
Biological Activity
Miconazole nitrate is a antifungal agent. Inhibits lanosterol demethylase and induces formation of reactive oxygen species. Enhances the generation of mature oligodendrocytes from progenitor cells in vitro and promotes myelination in vivo. Attenuates disease severity in a mouse model of multiple sclerosis. Brain penetrant.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.
Hubler et al.
Nature, 2018;560:372 -
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.
Najim et al.
Nature, 2015;522:216 -
Effect of miconazole on intracellular Ca2+ levels and proliferation in human osteosarcoma cells.
Chang et al.
Life Sci., 2005;76:2091
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Miconazole nitrate
There are currently no reviews for this product. Be the first to review Miconazole nitrate and earn rewards!
Have you used Miconazole nitrate?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
