Minoxidil
Chemical Name: 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
Purity: ≥99%
Biological Activity
Minoxidil is an antihypertensive. Antialopecia agent. Kir6 channel (KATP) activator.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells.
Lachgar et al.
Br.J.Dermatol., 1998;138:407 -
Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil.
Meisheri et al.
Biochem.Pharmacol., 1993;45:271 -
Effects of the arterial vasodilator minoxidil on cardiovascular structure and sympathetic activity in spontaneously hypertensive rats.
Tsoporis et al.
J.Hypertens., 1993;11:1337
Product Datasheets
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Citation for Minoxidil
The citations listed below are publications that use Tocris products. Selected citations for Minoxidil include:
1 Citation: Showing 1 - 1
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Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel.
Authors: Sun Et al.
Sci Rep 2014;4:4934
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