(±)-ML 209

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions.
   Huang et al.
   Nature, 2015;528:517
2. REV-ERB and ROR nuclear receptors as drug targets.
   Kojetin et al.
   Nat.Rev.Drug Discov., 2014;13:197
3. Identification of Potent and Selective RORγ Antagonists.
   Huang et al.
   Probe Reports from the NIH Molecular Libraries Program, 2010;
4. Discovery of novel N-(5-(arylcarbonyl)thiazol-2-yl)amides and N-(5-(arylcarbonyl)thiophen-2-yl)amides as potent RORγt inhibitors.
   Wang et al.
   Bioorg.Med.Chem., 2014;22:692

Product Datasheets