Home / Nrf2 Activators / ML 334

ML 334

Catalog #: 5625
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5625/5
ML 334 | CAS No. 1432500-66-7 | Nrf2 Activators
1 Image
Description: Inhibitor of Keap1- Nrf2 interaction
Alternative Names: LH601A

Chemical Name: (1S,2R)-2-[[(1S)-1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]cyclohexanecarboxylic acid

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

ML 334 is an Nrf2 activator; inhibits Nrf2/Keap1 interaction (Kd = 1 μM). Promotes Nrf2 nuclear translocation and induces antioxidant response element (ARE) activity in vitro. Cell permeable.

Technical Data

M.Wt:
446.5
Formula:
C26H26N2O5
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1432500-66-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for ML 334

The citations listed below are publications that use Tocris products. Selected citations for ML 334 include:

1 Citation: Showing 1 - 1

  1. A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy.
    Authors: Vladimir Et al.
    Redox Biol  2021;48:102186

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for ML 334

There are currently no reviews for this product. Be the first to review ML 334 and earn rewards!

Have you used ML 334?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.