Home / C1qR1/CD93 / Mouse C1qR1/CD93 Antibody

Mouse C1qR1/CD93 Antibody

Catalog #: AF1696
8 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF1696
AF1696-SP
Product Details
Citations (8)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse C1qR1/CD93 Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse C1q R1/CD93 in direct ELISAs and Western blots.
Source
Polyclonal Sheep IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse C1q R1/CD93
Ala23-Asn572
Accession # O89103
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse C1q R1/CD93

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: C1qR1/CD93

C1q R1, also known as C1q Rp, CD93, Cell Surface Antigen AA4 and lymphocyte antigen 68, is a type I transmembrane protein. It contains a C-type lectin family domain and five EGF-like domains in its extracellular region, as well as a tyrosine kinase-recognition motif in its cytoplasmic region. It is most abundantly expressed on endothelial cells and platelets and is also expressed in neutrophils, glial cells and monocytes. C1q R1 is a marker for early multipotent hematopoietic cells and may participate in C1q/MBL/SPA-mediated enhancement of phagocytic function by monocytes.

Long Name
Complement Component C1q Receptor
Entrez Gene IDs
22918 (Human); 17064 (Mouse); 84398 (Rat)
Alternate Names
AA4 Antigen; C1q R1; C1q receptor 1; C1q Rp; C1q/MBL/SPA receptor; C1qR(P); C1qR1; C1qRp; CD93 antigenC1qR; CD93 molecule; CD93; CDw93C1QR1; Collectin Receptor; Complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; Matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4

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Citations for Mouse C1qR1/CD93 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

8 Citations: Showing 1 - 8
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  1. A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state
    Authors: Ghazal Zekavat, Raha Mozaffari, Vanessa J. Arias, Susan Y. Rostami, Armen Badkerhanian, Andrea J. Tenner et al.
    Immunogenetics
  2. Significance of Soluble CD93 in Type 2 Diabetes as a Biomarker for Diabetic Nephropathy: Integrated Results from Human and Rodent Studies
    Authors: M Lee, HS Park, MY Choi, HZ Kim, SJ Moon, JY Ha, A Choi, YW Park, JS Park, EC Shin, CW Ahn, S Kang
    J Clin Med, 2020-05-08;9(5):.
  3. SOX4 promotes vascular abnormality in glioblastoma and is a novel target to improve drug delivery
    Authors: Yao, K;Yang, M;Shu, M;Wang, T;Gao, D;Zhou, L;Wang, G;Zhang, Z;Tang, J;
    Translational oncology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  4. SproutAngio: an open-source bioimage informatics tool for quantitative analysis of sprouting angiogenesis and lumen space
    Authors: Beter, M;Abdollahzadeh, A;Pulkkinen, HH;Huang, H;Orsenigo, F;Magnusson, PU;Yl�-Herttuala, S;Tohka, J;Laakkonen, JP;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  5. CD93 promotes ?1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
    Authors: R Lugano, K Vemuri, D Yu, M Bergqvist, A Smits, M Essand, S Johansson, E Dejana, A Dimberg
    J. Clin. Invest., 2018-06-25;128(8):3280-3297.
    Species: Human, Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  6. Membrane-associated CD93 regulates leukocyte migration and C1q-hemolytic activity during murine peritonitis.
    Authors: Greenlee-Wacker MC, Briseno C, Galvan M, Moriel G, Velazquez P, Bohlson SS
    J. Immunol., 2011-08-17;187(6):3353-61.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
    Applications: ELISA Development
  7. Discovery and validation of biomarkers that respond to treatment with brivanib alaninate, a small-molecule VEGFR-2/FGFR-1 antagonist.
    Authors: Ayers M, Fargnoli J, Lewin A, Wu Q, Platero JS
    Cancer Res., 2007-07-15;67(14):6899-906.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  8. Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution
    Authors: Fabrizio Orsenigo, Lei Liu Conze, Suvi Jauhiainen, Monica Corada, Francesca Lazzaroni, Matteo Malinverno et al.
    eLife

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