Mouse CCR2 PE-conjugated Antibody Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
Detection of CCR2 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CCR2 PE-conjugated Monoclonal Antibody (Catalog # FAB5538P) and Rat Anti-Mouse Gr-1/Ly-6G Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB1037F). Quadrant marker was set based on isotype control antibody staining (Catalog # IC013P). View our protocol for Staining Membrane-associated Proteins.
Detection of Mouse CCR2 by Flow Cytometry Depletion of CCR2 cells enhances tumor radiosensitivity. a Scheme of treatment. b Treated tumor was measured every 3-4 days for 33 days starting from the day of radiation (n = 10). c Percentage of mice still bearing tumor at the end of the treatments (n = 10), P < 0.05. d Flow cytometry profile of CCR2+Ly6Chi in tumors 3 days post the start of treatments. Left, representative flow graph, gated on CD45+CD11b+cells; Middle, percentage of CD45+; Right, absolute number of cells (n = 4). NS, non-significant.*P < 0.05; **P < 0.01; ***P < 0.001. Each experiment was repeated 3 times. Data are presented as mean ± s.e.m Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/29170400), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Mouse CCR2 by Flow Cytometry MDSC depletion enhances tumor response to radiation and STING agonist cGAMP treatment. a Flow cytometry analysis of immune CCR2+Ly6chi cells 3 days after IR (n = 3). b Tumor growth curves; n = 6; c percentage of tumor bearing mice ending on 33 days after starting of the treatments. d, e ratios of percentage of CD8 over CCR2+Ly6chi and Treg cells in treated tumors, respectively. n = 3. *P < 0.05; **P < 0.01. The experiments were repeated three times. Data are presented as mean ± s.e.m Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/29170400), licensed under a CC-BY license. Not internally tested by R&D Systems.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CCR2
CCR2, also known as CD192, is a 38 kDa 7TM chemokine receptor that binds CCL2, CCL7, CCL8, CCL12 (in mouse only) and CCL13. CCR2 is expressed by multiple hematopoietic cells plus, endothelial cells, fibroblasts, and smooth muscle cells. It functions as an HIV fusion co-factor and facilitates T cell recruitment during inflammation. Mouse CCR2 shares 67% and 95% aa sequence identity with human and rat CCR2, respectively.
Product Datasheets
Citations for Mouse CCR2 PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development
Authors: PPSJ Khedoe, S de Kleijn, AM van Oevere, JJ Plomp, HC de Boer, M van Pel, PCN Rensen, JFP Berbée, PS Hiemstra
PLoS ONE, 2017-09-14;12(9):e0183741.
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Functionally and Metabolically Divergent Melanoma-Associated Macrophages Originate from Common Bone-Marrow Precursors
Authors: Gabriela A. Pizzurro, Kate Bridges, Xiaodong Jiang, Aurobind Vidyarthi, Kathryn Miller-Jensen, Oscar R. Colegio
Cancers (Basel)
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Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization
Authors: Jing Zhang, Jonathan Muri, Gillian Fitzgerald, Tatiane Gorski, Roberto Gianni-Barrera, Evi Masschelein et al.
Cell Metabolism
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Cardiac resident macrophages are involved in hypoxia-induced postnatal cardiomyocyte proliferation
Authors: Bo Liu, Hua-Gang Zhang, Yun Zhu, Yun-Han Jiang, Gui-Ping Luo, Fu-Qin Tang et al.
Molecular Medicine Reports
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Monocytes transition to macrophages within the inflamed vasculature via monocyte CCR2 and endothelial TNFR2
Authors: Vijayashree Mysore, Suhail Tahir, Kazuhiro Furuhashi, Jatin Arora, Florencia Rosetti, Xavier Cullere et al.
Journal of Experimental Medicine
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Pro-Inflammatory Priming of the Brain: The Underlying Cause of Parkinson's Disease
Authors: Martins, AC;Lima, IS;P�go, AC;S� Pereira, I;Martins, G;Kapit�o, A;Gozzelino, R;
International journal of molecular sciences
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Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue
Authors: Marco Rosina, Veronica Ceci, Riccardo Turchi, Chuan Chuan, Nicholas Borcherding, Francesca Sciarretta et al.
Cell Metabolism
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Fetal CCL2 signaling mediates offspring social behavior and recapitulates effects of prenatal stress
Authors: Chen, HJ;Galley, JD;Verosky, BG;Yang, FA;Rajasekera, TA;Bailey, MT;Gur, TL;
Brain, behavior, and immunity
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Regulation of High-fat Diet-induced Liver Fibrosis by SOCS1 Expression in Hepatic Stellate Cells
Authors: Kandhi, R;Menendez, A;Ramanathan, S;Ilangumaran, S;
Journal of clinical and experimental hepatology
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Gut Dysbiosis: A Target for Protective Interventions against Parkinson's Disease
Authors: Lima, IS;P�go, AC;Martins, AC;Prada, AR;Barros, JT;Martins, G;Gozzelino, R;
Microorganisms
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
CD169+ macrophage intrinsic IL-10 production regulates immune homeostasis during sepsis
Authors: ST Yeung, LJ Ovando, AJ Russo, VA Rathinam, KM Khanna
Cell Reports, 2023-03-02;42(3):112171.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Loss of T�cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages
Authors: HC West, J Davies, S Henderson, OK Adegun, S Ward, IR Ferrer, CA Tye, AF Vallejo, L Jardine, M Collin, ME Polak, CL Bennett
Cell Reports, 2022-05-17;39(7):110819.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence
Authors: SR Anderson, JM Roberts, N Ghena, EA Irvin, J Schwakopf, IB Cooperstei, A Bosco, ML Vetter
Elife, 2022-04-28;11(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Environmental eustress improves postinfarction cardiac repair via enhancing cardiac macrophage survival
Authors: PY Bai, SQ Chen, DL Jia, LH Pan, CB Liu, J Liu, W Luo, Y Yang, MY Sun, NF Wan, WW Rong, AJ Sun, JB Ge
Science Advances, 2022-04-27;8(17):eabm3436.
Species: Mouse
Sample Types: Whole Cell
Applications: Flow Cytometry -
The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD
Authors: G Günes Güns, TM Conlon, A Jeridi, R Kim, Z Ertüz, NJ Lang, M Ansari, M Novikova, D Jiang, M Strunz, M Gaianova, C Hollauer, C Gabriel, I Angelidis, S Doll, JC Pestoni, SL Edelmann, MS Kohlhepp, A Guillot, K Bassler, HP Van Eeckho, Ö Kayalar, N Konyalilar, T Kanashova, S Rodius, C Ballester-, CM Genes Robl, N Smirnova, M Rehberg, C Agarwal, I Krikki, B Piavaux, SE Verleden, B Vanaudenae, M Königshoff, G Dittmar, KR Bracke, JL Schultze, H Watz, O Eickelberg, T Stoeger, G Burgstalle, F Tacke, V Heissmeyer, Y Rinkevich, H Bayram, HB Schiller, M Conrad, R Schneider, AÖ Yildirim
Nature Communications, 2022-03-14;13(1):1303.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Angiotensin-(1-7)/MasR axis promotes migration of monocytes/macrophages with a regulatory phenotype to perform phagocytosis and efferocytosis
Authors: I Zaidan, LP Tavares, MA Sugimoto, KM Lima, GL Negreiros-, LC Teixeira, TC Miranda, BV Valiate, A Cramer, JP Vago, GH Campolina-, JA Souza, LC Grossi, V Pinho, MJ Campagnole, RAS Santos, MM Teixeira, I Galvão, LP Sousa
JCI Insight, 2022-01-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Irbesartan, an angiotensin II type 1 receptor blocker, inhibits colitis-associated tumourigenesis by blocking the MCP-1/CCR2 pathway
Authors: K Hachiya, M Masuya, N Kuroda, M Yoneda, J Tsuboi, K Nagaharu, K Nishimura, T Shiotani, K Ohishi, I Tawara, N Katayama
Scientific Reports, 2021-10-07;11(1):19943.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
Authors: LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller
Nature Communications, 2021-06-10;12(1):3543.
Species: Mouse
Sample Types: Exosomes
Applications: Flow Cytometry -
Hepatocyte-specific glucose-6-phosphatase deficiency disturbs platelet aggregation and decreases blood monocytes upon fasting-induced hypoglycemia
Authors: AM La Rose, V Bazioti, JA Hoogerland, AF Svendsen, AG Groenen, M van Faasse, MGS Rutten, NJ Kloosterhu, B Dethmers-A, JH Nijland, G Mithieux, F Rajas, F Kuipers, MV Lukens, O Soehnlein, MH Oosterveer, M Westerterp
Molecular Metabolism, 2021-06-04;53(0):101265.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Sensory�neuron-derived TAFA4 promotes macrophage tissue repair functions
Authors: G Hoeffel, G Debroas, A Roger, R Rossignol, J Gouilly, C Laprie, L Chasson, PV Barbon, A Balsamo, A Reynders, A Moqrich, S Ugolini
Nature, 2021-05-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
CCR2 of Tumor Microenvironmental Cells Is a Relevant Modulator of Glioma Biology
Authors: M Felsenstei, A Blank, AD Bungert, A Mueller, A Ghori, I Kremenetsk, O Rung, T Broggini, K Turkowski, L Scherschin, J Raggatz, P Vajkoczy, S Brandenbur
Cancers (Basel), 2020-07-13;12(7):.
Species: Mouse
Sample Types: Whole Cell
Applications: Flow Cytometry -
Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization
Authors: J Lian, AJ Ozga, CL Sokol, AD Luster
Cell Rep, 2020-05-26;31(8):107679.
Species: Mouse
Sample Types:
Applications: IHC -
A gammaherpesvirus licenses CD8 T cells to protect the host from pneumovirus-induced immunopathologies
Authors: M Dourcy, C Maquet, L Dams, G Gilliaux, J Javaux, D Desmecht, M Mack, BG Dewals, B Machiels, L Gillet
Mucosal Immunol, 2020-05-18;0(0):.
Species: Mouse
Sample Types:
Applications: Flow Cytometry -
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Authors: Bosteels C, Neyt K, Vanheerswynghels M, van Helden M, Sichien D, Debeuf N, De Prijck S, Bosteels V, Vandamme N, Martens L, Saeys Y, Louagie E, Lesage M, Williams D, Tang S, Mayer J, Ronchese F, Scott C, Hammad H, Guilliams M, Lambrecht B
Immunity, 2020-05-08;0(0):.
Species: Mouse
Sample Types: T-cells
Applications: Flow Cytometry -
CCR2 signaling in breast carcinoma cells promotes tumor growth and invasion by promoting CCL2 and suppressing CD154 effects on the angiogenic and immune microenvironments
Authors: G Brummer, W Fang, C Smart, B Zinda, N Alissa, C Berkland, D Miller, N Cheng
Oncogene, 2019-12-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy
Authors: L Shi, J Wang, N Ding, Y Zhang, Y Zhu, S Dong, X Wang, C Peng, C Zhou, L Zhou, X Li, H Shi, W Wu, X Long, C Wu, W Liao
Nat Commun, 2019-11-28;10(1):5421.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Flow Cytometry -
Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis
Authors: X Liu, DL Clemens, JA Grunkemeye, JD Price, K O'Connell, NM Chapman, P Storz, H Wen, JL Cox, WL Reid, MA Hollingswo, S Thayer
Sci Rep, 2019-07-23;9(1):10656.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Innate Lymphoid Cells in the Induction of Obesity
Authors: T Sasaki, K Moro, T Kubota, N Kubota, T Kato, H Ohno, S Nakae, H Saito, S Koyasu
Cell Rep, 2019-07-02;28(1):202-217.e7.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis
Authors: C Miyabe, Y Miyabe, L Moreno, J Lian, RA Rahimi, NN Miura, N Ohno, Y Iwakura, T Kawakami, AD Luster
J. Clin. Invest., 2019-06-06;130(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Zearalenone inhibits T cell chemotaxis by inhibiting cell adhesion and migration related proteins
Authors: G Cai, S Pan, N Feng, H Zou, J Gu, Y Yuan, X Liu, Z Liu, J Bian
Ecotoxicol. Environ. Saf., 2019-03-21;175(0):263-271.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis
Authors: J Li, S Wada, LK Weaver, C Biswas, EM Behrens, Z Arany
JCI Insight, 2019-03-07;5(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia
Authors: C Widmann, C Gandin, A Petit-Pait, M Lazdunski, C Heurteaux
Sci Rep, 2018-12-24;8(1):18062.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens
Authors: S Normand, N Waldschmit, A Neerincx, RJ Martinez-T, C Chauvin, A Couturier-, O Boulard, L Cobret, F Awad, L Huot, A Ribeiro-Ri, K Lautz, R Ruez, M Delacre, C Bondu, M Guilliams, C Scott, A Segal, S Amselem, D Hot, S Karabina, E Bohn, B Ryffel, LF Poulin, TA Kufer, M Chamaillar
Nat Commun, 2018-12-17;9(1):5338.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
TNF, but not hyperinsulinemia or hyperglycemia, is a key driver of obesity-induced monocytosis revealing that inflammatory monocytes correlate with insulin in obese male mice
Authors: JA Breznik, A Naidoo, KP Foley, C Schulz, TC Lau, D Loukov, DM Sloboda, DME Bowdish, JD Schertzer
Physiol Rep, 2018-12-01;6(23):e13937.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Methylprednisolone treatment enhances early recovery following surgical decompression for degenerative cervical myelopathy without compromise to the systemic immune system
Authors: PM Vidal, A Ulndreaj, A Badner, J Hong, MG Fehlings
J Neuroinflammation, 2018-08-06;15(1):222.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions
Authors: M Evrard, IWH Kwok, SZ Chong, KWW Teng, E Becht, J Chen, JL Sieow, HL Penny, GC Ching, S Devi, JM Adrover, JLY Li, KH Liong, L Tan, Z Poon, S Foo, JW Chua, IH Su, K Balabanian, F Bachelerie, SK Biswas, A Larbi, WYK Hwang, V Madan, HP Koeffler, SC Wong, EW Newell, A Hidalgo, F Ginhoux, LG Ng
Immunity, 2018-02-20;48(2):364-379.e8.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry, Mass Cytometry -
Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1
Authors: F Sasaki, T Koga, K Saeki, T Okuno, S Kazuno, T Fujimura, Y Ohkawa, T Yokomizo
PLoS ONE, 2017-09-18;12(9):e0185133.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Recruitment of neutrophils mediated by V?2 ?? T cells deteriorate liver fibrosis induced by Schistosoma japonicum infection in C57BL/6 mice
Authors: L Zheng, Y Hu, Y Wang, X Huang, Y Xu, Y Shen, J Cao
Infect. Immun., 2017-07-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Delayed decompression exacerbates ischemia-reperfusion injury in cervical compressive myelopathy
Authors: PM Vidal, SK Karadimas, A Ulndreaj, AM Laliberte, L Tetreault, S Forner, J Wang, WD Foltz, MG Fehlings
JCI Insight, 2017-06-02;2(11):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Distinct functions of CXCR4, CCR2, and CX3CR1 direct dendritic cell precursors from the bone marrow to the lung
Authors: H Nakano, MR Lyons-Cohe, GS Whitehead, K Nakano, DN Cook
J. Leukoc. Biol, 2017-02-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
The Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo
Authors: N Lavender, J Yang, SC Chen, J Sai, CA Johnson, P Owens, GD Ayers, A Richmond
BMC Cancer, 2017-01-31;17(1):88.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Mature dendritic cell derived from cryopreserved immature dendritic cell shows impaired homing ability and reduced anti-viral therapeutic effects
Sci Rep, 2016-12-13;6(0):39071.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Treatment with cestode parasite antigens recruits CCR2+ myeloid cells, the adoptive transfer of which ameliorates colitis
Infect Immun, 2016-11-18;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function
Proc Natl Acad Sci USA, 2016-09-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice
J Am Heart Assoc, 2016-09-15;5(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Alternatively activated macrophages determine repair of the infarcted adult murine heart
J Clin Invest, 2016-05-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Tumor necrosis factor drives increased splenic monopoiesis in old mice
Authors: D Loukov, A Naidoo, A Puchta, JL Marin, DM Bowdish
J Leukoc Biol, 2016-04-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
AMPK-Activated Protein Kinase Suppresses Ccr2 Expression by Inhibiting the NF-kappaB Pathway in RAW264.7 Macrophages.
Authors: Kumase F, Takeuchi K, Morizane Y, Suzuki J, Matsumoto H, Kataoka K, Al-Moujahed A, Maidana D, Miller J, Vavvas D
PLoS ONE, 2016-01-22;11(1):e0147279.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Dynamics and Transcriptomics of Skin Dendritic Cells and Macrophages in an Imiquimod-Induced, Biphasic Mouse Model of Psoriasis.
Authors: Terhorst D, Chelbi R, Wohn C, Malosse C, Tamoutounour S, Jorquera A, Bajenoff M, Dalod M, Malissen B, Henri S
J Immunol, 2015-10-14;195(10):4953-61.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis.
Authors: Coffelt S, Kersten K, Doornebal C, Weiden J, Vrijland K, Hau C, Verstegen N, Ciampricotti M, Hawinkels L, Jonkers J, de Visser K
Nature, 2015-03-30;522(7556):345-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Development of a pHrodo-based assay for the assessment of in vitro and in vivo erythrophagocytosis during experimental trypanosomosis.
Authors: Stijlemans, Benoit, Cnops, Jennifer, Naniima, Peter, Vaast, Axel, Bockstal, Viki, De Baetselier, Patrick, Magez, Stefan
PLoS Negl Trop Dis, 2015-03-05;9(3):e0003561.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
CD11b is protective in complement-mediated immune complex glomerulonephritis.
Authors: Alexander J, Chaves L, Chang A, Jacob A, Ritchie M, Quigg R
Kidney Int, 2015-01-07;87(5):930-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Male bovine GH transgenic mice have decreased adiposity with an adipose depot-specific increase in immune cell populations.
Authors: Benencia, Fabian, Harshman, Stephani, Duran-Ortiz, Silvana, Lubbers, Ellen R, List, Edward O, Householder, Lara, Al-Naeeli, Mawadda, Liang, Xiaoyu, Welch, Lonnie, Kopchick, John J, Berryman, Darlene
Endocrinology, 2014-12-18;156(5):1794-803.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Batf3-dependent CD103+ dendritic cells are major producers of IL-12 that drive local Th1 immunity against Leishmania major infection in mice.
Authors: Martinez-Lopez M, Iborra S, Conde-Garrosa R, Sancho D
Eur J Immunol, 2014-11-28;45(1):119-29.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Molecular and cellular neuroinflammatory status of mouse brain after systemic lipopolysaccharide challenge: importance of CCR2/CCL2 signaling.
Authors: Cazareth J, Guyon A, Heurteaux C, Chabry J, Petit-Paitel A
J Neuroinflammation, 2014-07-28;11(0):132.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Loss of CD11b exacerbates murine complement-mediated tubulointerstitial nephritis.
Authors: Chaves, Lee Dani, Bao, Lihua, Wang, Ying, Chang, Anthony, Haas, Mark, Quigg, Richard
PLoS ONE, 2014-03-14;9(3):e92051.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
The monocyte to macrophage transition in the murine sterile wound.
Authors: Crane, Meredith, Daley, Jean M, van Houtte, Olivier, Brancato, Samielle, Henry, William, Albina, Jorge E
PLoS ONE, 2014-01-22;9(1):e86660.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis.
Authors: Zheng, Jiao, Yang, Min, Shao, Jianghua, Miao, Yanju, Han, Jiahuai, Du, Jie
Mol Cancer, 2013-11-18;12(1):141.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Obesity alters adipose tissue macrophage iron content and tissue iron distribution.
Authors: Orr J, Kennedy A, Anderson-Baucum E, Webb C, Fordahl S, Erikson K, Zhang Y, Etzerodt A, Moestrup S, Hasty A
Diabetes, 2013-10-15;63(2):421-32.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells.
Authors: Yoshimura T, Howard O, Ito T, Kuwabara M, Matsukawa A, Chen K, Liu Y, Liu M, Oppenheim J, Wang J
PLoS ONE, 2013-03-18;8(3):e58791.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction
Authors: Damien N. Barnette, Thomas J. Cahill, Mala Gunadasa-Rohling, Carolyn A. Carr, Matthew Freeman, Paul R. Riley
JCI Insight
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Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the A beta 42:A beta 40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
Authors: Meilandt W J, Ngu H et al.
J Neurosci
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CD8+ T cells in the central nervous system of mice with herpes simplex infection are highly activated and express high levels of CCR5 and CXCR3
Authors: Liza Lind, Alexandra Svensson, Karolina Thörn, Malgorzata Krzyzowska, Kristina Eriksson
Journal of NeuroVirology
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The white adipose tissue is a reservoir for memory T cells that promotes protective memory responses to infection
Authors: Seong-Ji Han, Arielle Glatman Glatman Zaretsky, Vinicius Andrade-Oliveira, Nicholas Collins, Amiran Dzutsev, Jahangheer Shaik et al.
Immunity
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Host STING-dependent MDSC mobilization drives extrinsic radiation resistance
Authors: Liang H, Deng L, Hou Y et al.
Nat Commun.
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A novel role for C–C motif chemokine receptor 2 during infection with hypervirulent Mycobacterium tuberculosis
Authors: Micah D. Dunlap, Nicole Howard, Shibali Das, Ninecia Scott, Mushtaq Ahmed, Oliver Prince et al.
Mucosal Immunology
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Inhibition of a BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage inflammatory dendritic cells and enhances anti-tumor T cell immunity
Authors: Madhav D. Sharma, Rafal Pacholczyk, Huidong Shi, Zuzana J. Berrong, Yousef Zakharia, Austin Greco et al.
Immunity
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Works well on pancreatic myeloid cells, but unfortunately requires a 1:50 dilution.