Mouse ChemR23 PE-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB7610P-100UG
Detection of ChemR23 in RAW 264.7 Mouse Cell Line by Flow Cytometry.
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Product Details
Citations (2)
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Reviews (1)

Mouse ChemR23 PE-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse ChemR23 in flow cytometry
Source
Monoclonal Rat IgG2B Clone # 477806
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
NS0 mouse myeloma cell line transfected with mouse ChemR23
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of ChemR23 antibody in RAW 264.7 Mouse Cell Line antibody by Flow Cytometry. View Larger

Detection of ChemR23 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse ChemR23 PE-conjugated Monoclonal Antibody (Catalog # FAB7610P, filled histogram) or isotype control antibody (Catalog # IC013P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Reconstitution Calculator

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: ChemR23

ChemR23 is a chemoattractant receptor expressed on dendritic cells and activated macrophages. ChemR23 binds Chemerin and functions as a coreceptor for SIV and some primary HIV-1 strains (1).

References
  1. Samson, M. et al. (1998) Eur. J. Immunol. 28:1689.
Long Name
Chemokine-like Receptor 1/Orphan G Protein-coupled Receptor ChemR23
Entrez Gene IDs
1240 (Human); 14747 (Mouse); 60669 (Rat)
Alternate Names
CHEMERINR; chemokine receptor-like 1; chemokine-like receptor 1; ChemR23; cmklr1; Dez; Gpcr27; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; MGC126105; MGC126106; orphan G-protein coupled receptor, Dez

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Citations for Mouse ChemR23 PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Agonist anti-ChemR23 mAb reduces tissue neutrophil accumulation and triggers chronic inflammation resolution
    Authors: C Trilleaud, V Gauttier, K Biteau, I Girault, L Belarif, C Mary, S Pengam, G Teppaz, V Thepenier, R Danger, G Robert-Sie, M Néel, S Bruneau, A Glémain, A Néel, A Poupon, JF Mosnier, G Chêne, M Dubourdeau, G Blancho, B Vanhove, N Poirier
    Science Advances, 2021-04-02;7(14):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  2. Endothelial cell-derived chemerin promotes dendritic cell transmigration.
    Authors: Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S
    J Immunol, 2014-01-27;192(5):2366-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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Mouse ChemR23 PE-conjugated Antibody
By Jim Hsiao on 05/08/2018
Application: Flow Sample Tested: Mouse spleenocytes Species: Mouse