Mouse CXCL1/KC Quantikine ELISA Kit Summary
Product Summary
Recovery
The recovery of mouse KC spiked to three levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Supernates (n=7) | 98 | 89-103 |
Serum (n=9) | 95 | 83-104 |
Linearity
Scientific Data
Detection of Mouse CXCL1/GRO alpha/KC/CINC-1 by ELISA STAT3 regulates chemoattractive CXCL1 expression.(a) ELISA of CXCL1 levels in lung lysates and BAL at 6 and 13 weeks post AdCre. Data were analysed by Student’s t-test and shown as mean±s.d., n≥7 mice per genotype and time point. (b) Representative in situ hybridization with probes specific for murine Cxcl1 (AS) in lung tumours at 13 weeks post AdCre. Sense probes (S) were used as negative control and surfactant protein C (SP-C) as lung epithelial maker. Scale bar, 100 μm. (c) Kaplan–Meier plot showing overall survival of lung adenocarcinoma patient samples harbouring smoking history with high or low IL-8 mRNA expression (expression values of upper quartile, log-rank test) n≥35–104 per group. (d) Human A549 lung cancer cell line (KRASG12S mutated) was stimulated with designated cytokines for indicated time points. IL-8 or CXCL1 expression was analysed via qRT–PCR. Data were analysed by one-way ANOVA with Tukey’s multiple comparison test and shown as mean±s.d. (e) A549 cells transducted with lentiviral vectors expressing nonspecific scrambled small hairpin (sh)RNA or shRNA against STAT3 were stimulated with indicated cytokines for 60 min. Data were analysed by one-way ANOVA with Tukey’s multiple comparison test and shown as mean±s.d. (f) Primary pneumocytes were isolated and infected with AdCre. 120 h post infection cells were stimulated with indicated cytokines for 60 min. Cxcl1 expression was analysed by qRT–PCR. Data are shown as mean±s.e.m. (g) Murine 3T3 fibroblasts and STAT3 overexpressing 3T3 fibroblasts were stimulated as in f. Cxcl1 expression was analysed by qRT–PCR. Data were analysed by one-way ANOVA with Tukey’s multiple comparison test and shown as mean± s.d. Values in d–g are presented as fold change of relative mRNA expression compared with each unstimulated individual cell line. At least two independent experiments with three individual plates per stimulation were performed. For all graphs: *P<0.05; **P<0.01; ***P<0.001. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/ncomms7285), licensed under a CC-BY license. Not internally tested by R&D Systems.
Product Datasheets
Preparation and Storage
Background: CXCL1/GRO alpha/KC/CINC-1
CXCL1/GRO alpha, also known as KC in mouse and CINC-1 in rat, is a member of the CXC family of chemokines. Human CXCL1/GRO alpha is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 57% and 59% amino acid sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl3 gene is homologous to human CXCL1/GRO alpha protein. Human CXCL1/GRO alpha can be cleaved into three isoforms CXCL1/GRO alpha (aa 4-73), CXCL1/GRO alpha (aa 5-73), and CXCL1/GRO alpha (aa 6-73) which show higher activity than the full length protein. CXCL1/GRO alpha is secreted by mast cells and macrophages whereupon it acts as a chemoattractant for neutrophils.
Citations for Mouse CXCL1/KC Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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ACSL6-activated IL-18R1-NF-?B promotes IL-18-mediated tumor immune evasion and tumor progression
Authors: Di, Y;Wang, Z;Xiao, J;Zhang, X;Ye, L;Wen, X;Qin, J;Lu, L;Wang, X;He, W;
Science advances
Species: Mouse
Sample Types: Tissue Homogenates
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Plexin C1 influences immune response to intracellular LPS and survival in murine sepsis
Authors: Bernard, A;Eggstein, C;Tang, L;Keller, M;Körner, A;Mirakaj, V;Rosenberger, P;
Journal of biomedical science
Species: Transgenic Mouse
Sample Types: Cell Culture Supernates, Peritoneal Lavage Fluid
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Driver gene KRAS aggravates cancer-associated stroke outcomes
Authors: Yan, H;Sasaki, T;Gon, Y;Nishiyama, K;Kanki, H;Mochizuki, H;
Thrombosis research
Species: Xenograft
Sample Types: Serum
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Ethanol Extracts from the Aerial Parts of Inula japonica and Potentilla chinensis Alleviate Airway Inflammation in Mice That Inhaled Particulate Matter 10 and Diesel Particulate Matter
Authors: Jung, SH;Chung, KS;Na, CS;Ahn, HS;Shin, YK;Lee, KT;
Nutrients
Species: Mouse
Sample Types: BALF
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LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis
Authors: Sha, L;Li, J;Shen, H;Wang, Q;Meng, P;Zhang, X;Deng, Y;Zhu, W;Xu, Q;
Cell reports
Species: Mouse
Sample Types: Cell Culture Supernates
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Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells
Authors: Jadi, PK;Dave, A;Issa, R;Tabbasum, K;Okurowska, K;Samarth, A;Urwin, L;Green, LR;Partridge, LJ;MacNeil, S;Garg, P;Monk, PN;Roy, S;
The ocular surface
Species: Mouse
Sample Types: Tissue Homogenates
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Polysialylation controls immune function of myeloid cells in murine model of pneumococcal pneumonia
Authors: Shinde, P;Kiepas, A;Zhang, L;Sudhir, S;Konstantopoulos, K;Stamatos, NM;
Cell reports
Species: Mouse
Sample Types: Tissue Homogenates
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The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-?B
Authors: Fei, X;Huang, J;Li, F;Wang, Y;Shao, Z;Dong, L;Wu, Y;Li, B;Zhang, X;Lv, B;Zhao, Y;Weng, Q;Chen, K;Zhang, M;Yang, S;Zhang, C;Zhang, M;Li, W;Ying, S;Sun, Q;Chen, Z;Shen, H;
Cell reports
Species: Mouse
Sample Types: BALF, Cell Culture Supernates
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Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles
Authors: Graca, FA;Stephan, A;Minden-Birkenmaier, BA;Shirinifard, A;Wang, YD;Demontis, F;Labelle, M;
Nature communications
Species: Mouse
Sample Types: Plasma
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Mechanism and intervention of murine transfusion-related acute lung injury caused by anti-CD36 antibodies
Authors: DW Chen, T Kang, XZ Xu, WJ Xia, X Ye, YB Wu, YR Xu, J Liu, H Ren, J Deng, YK Chen, HQ Ding, M Aslam, WM Zelek, BP Morgan, R Kapur, S Santoso, YS Fu
JCI Insight, 2023-03-22;0(0):.
Species: Mouse
Sample Types: BALF
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The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer
Authors: HW An, SH Seok, JW Kwon, AD Choudhury, JS Oh, DC Voon, DY Kim, JW Park
Cell Reports, 2022-12-27;41(13):111878.
Species: Mouse
Sample Types: Cell Culture Supernates
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Dasatinib attenuates airway inflammation of asthma exacerbation in mice induced by house dust mites and dsRNA
Authors: Y Nishimoto, D Ando, K Irie, I Kainuma, Y Katayama, S Sato, T Suzuki, M Harada, T Yoshida, K Ito, Y Kizawa
Biochemistry and Biophysics Reports, 2022-12-02;33(0):101402.
Species: Mouse
Sample Types: BALF
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Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells
Authors: K Thomas, L Zondler, N Ludwig, M Kardell, C Lüneburg, K Henke, S Mersmann, A Margraf, T Spieker, T Tekath, A Velic, R Holtmeier, J Hermann, V Jankowski, M Meersch, D Vestweber, M Westphal, J Roth, MA Schäfers, JA Kellum, CA Lowell, J Rossaint, A Zarbock
JCI Insight, 2022-11-08;7(21):.
Species: Mouse
Sample Types: Urine
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Brain motor and fear circuits regulate leukocytes during acute stress
Authors: WC Poller, J Downey, AA Mooslechne, N Khan, L Li, CT Chan, CS McAlpine, C Xu, F Kahles, S He, H Janssen, JE Mindur, S Singh, MG Kiss, L Alonso-Her, Y Iwamoto, RH Kohler, LP Wong, K Chetal, SJ Russo, RI Sadreyev, R Weissleder, M Nahrendorf, PS Frenette, M Divangahi, FK Swirski
Nature, 2022-05-30;0(0):.
Species: Mouse
Sample Types: Serum
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IL-36 signalling enhances a pro-tumorigenic phenotype in colon cancer cells with cancer cell growth restricted by administration of the IL-36R antagonist
Authors: K Baker, C O'Donnell, M Bendix, S Keogh, J Byrne, M O'Riordain, P Neary, A Houston, E Brint
Oncogene, 2022-04-01;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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The Transcription Factor SpoVG Is of Major Importance for Biofilm Formation of Staphylococcus epidermidis under In Vitro Conditions, but Dispensable for In Vivo Biofilm Formation
Authors: H Benthien, B Fresenborg, L Pätzold, MI Elhawy, S Huc-Brandt, C Beisswenge, G Krasteva-C, SL Becker, V Molle, JK Knobloch, M Bischoff
International Journal of Molecular Sciences, 2022-03-17;23(6):.
Species: Mouse
Sample Types: Tissue Homogenates
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Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in Gata1low Mice
Authors: M Zingariell, P Verachi, F Gobbo, F Martelli, M Falchi, M Mazzarini, M Valeri, G Sarli, C Marinaccio, J Melo-Carde, JD Crispino, AR Migliaccio
Biomolecules, 2022-01-30;12(2):.
Species: Mouse
Sample Types: Serum
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Intestinal microbe-dependent ?3 lipid metabolite alphaKetoA prevents inflammatory diseases in mice and cynomolgus macaques
Authors: T Nagatake, S Kishino, E Urano, H Murakami, N Kitamura, K Konishi, H Ohno, P Tiwari, S Morimoto, E Node, J Adachi, Y Abe, J Isoyama, K Sawane, T Honda, A Inoue, A Uwamizu, T Matsuzaka, Y Miyamoto, SI Hirata, A Saika, Y Shibata, K Hosomi, A Matsunaga, H Shimano, M Arita, J Aoki, M Oka, A Matsutani, T Tomonaga, K Kabashima, M Miyachi, Y Yasutomi, J Ogawa, J Kunisawa
Mucosal Immunology, 2022-01-10;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Biomimetic nanoparticles deliver mRNAs encoding costimulatory receptors and enhance T cell mediated cancer immunotherapy
Authors: W Li, X Zhang, C Zhang, J Yan, X Hou, S Du, C Zeng, W Zhao, B Deng, DW McComb, Y Zhang, DD Kang, J Li, WE Carson, Y Dong
Nature Communications, 2021-12-14;12(1):7264.
Species: Mouse
Sample Types: Plasma
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Natural Compound Resveratrol Attenuates TNF-Alpha-Induced Vascular Dysfunction in Mice and Human Endothelial Cells: The Involvement of the NF-kappaB Signaling Pathway
Authors: P Nallasamy, ZY Kang, X Sun, PV Anandh Bab, D Liu, Z Jia
International Journal of Molecular Sciences, 2021-11-19;22(22):.
Species: Mouse
Sample Types: Serum
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SLC7A2 deficiency promotes hepatocellular carcinoma progression by enhancing recruitment of myeloid-derived suppressors cells
Authors: S Xia, J Wu, W Zhou, M Zhang, K Zhao, J Liu, D Tian, J Liao
Cell Death & Disease, 2021-06-02;12(6):570.
Species: Mouse
Sample Types: Tissue Homogenates
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Activation of AhR-NQO1 signaling pathway protects against alcohol-induced liver injury by improving redox balance
Authors: H Dong, L Hao, W Zhang, W Zhong, W Guo, R Yue, X Sun, Z Zhou
Cellular and Molecular Gastroenterology and Hepatology, 2021-05-31;0(0):.
Species: Mouse
Sample Types: Serum
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Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection
Authors: T Lin, D Quellier, J Lamb, T Voisin, P Baral, F Bock, A Schönberg, R Mirchev, G Pier, I Chiu, M Gadjeva
PloS Pathogens, 2021-05-06;17(5):e1009557.
Species: Mouse
Sample Types: Tissue Homogenates
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Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses
Authors: MJ Strowitzki, G Kimmer, JS Wehrmann, AS Ritter, P Radhakrish, VM Opitz, C Tuffs, M Biller, J Kugler, U Keppler, JM Harnoss, J Klose, T Schmidt, A Blanco, CT Taylor, M Schneider
JCI Insight, 2021-03-30;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Alpha-1 antitrypsin deficiency impairs lung antibacterial immunity in mice
Authors: L Ostermann, R Maus, J Stolper, L Schütte, K Katsarou, S Tumpara, A Pich, C Mueller, S Janciauski, T Welte, UA Maus
JCI Insight, 2021-02-08;6(3):.
Species: Mouse
Sample Types: BALF
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Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1&alpha-NF-&kappaB Crosstalk In Vitro and In Vivo
Authors: SN Chang, DK Dey, ST Oh, WH Kong, KH Cho, EM Al-Olayan, BS Hwang, SC Kang, JG Park
International Journal of Molecular Sciences, 2020-12-04;21(23):.
Species: Mouse
Sample Types: Tissue Culture Supernates
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Cardiovascular tissue regeneration system based on multiscale scaffolds comprising double-layered hydrogels and fibers
Authors: YM Kook, S Hwang, H Kim, KJ Rhee, K Lee, WG Koh
Sci Rep, 2020-11-23;10(1):20321.
Species: Mouse
Sample Types: Serum
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Resolvin D1 attenuates the inflammatory process in mouse model of LPS-induced keratitis
Authors: F Petrillo, MC Trotta, C Bucolo, A Hermenean, A Petrillo, R Maisto, G Pieretti, M Pietropaol, F Ferraracci, C Gagliano, M Galdiero, M D'Amico
J Cell Mol Med, 2020-10-15;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Local microvascular leakage promotes trafficking of activated neutrophils to remote organs
Authors: C Owen-Woods, R Joulia, A Barkaway, L Rolas, B Ma, AF Nottebaum, KP Arkill, M Stein, T Girbl, M Golding, DO Bates, D Vestweber, MB Voisin, S Nourshargh
J. Clin. Invest., 2020-05-01;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci
Authors: A Famà, A Midiri, G Mancuso, C Biondo, G Lentini, R Galbo, MM Giardina, GV De Gaetano, L Romeo, G Teti, C Beninati
MBio, 2020-03-24;11(2):.
Species: Mouse
Sample Types: Tissue Lysates
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Cigarette smoke downregulates Nur77 to exacerbate inflammation in chronic obstructive pulmonary disease (COPD)
Authors: AT Reddy, SP Lakshmi, A Banno, SK Jadhav, I Pulikkal K, SC Kim, RC Reddy
PLoS ONE, 2020-02-21;15(2):e0229256.
Species: Mouse
Sample Types: Cell Culture Lysates
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Hydrogen Sulfide Attenuates Particulate Matter-Induced Emphysema and Airway Inflammation Through Nrf2-Dependent Manner
Authors: G Jia, S Yu, W Sun, J Yang, Y Wang, Y Qi, Y Chen
Front Pharmacol, 2020-02-07;11(0):29.
Species: Mouse
Sample Types: BALF
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Polarizing receptor activation dissociates fibroblast growth factor 2 mediated inhibition of myelination from its neuroprotective potential
Authors: K Thümmler, E Rom, T Zeis, M Lindner, S Brunner, JJ Cole, D Arseni, S Mücklisch, JM Edgar, N Schaeren-W, A Yayon, C Linington
Acta Neuropathol Commun, 2019-12-19;7(1):212.
Species: Mouse
Sample Types: Cell Culture Supernates
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Mesothelial Cell HIF1alpha Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk
Authors: PC Hart, HA Kenny, N Grassl, KM Watters, LM Litchfield, F Coscia, I Blaženovi?, L Ploetzky, O Fiehn, M Mann, E Lengyel, IL Romero
Cell Rep, 2019-12-17;29(12):4086-4098.e6.
Species: Mouse
Sample Types: Tissue Lysates
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Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain
Authors: GC Deng, M Lu, YY Zhao, Y Yuan, G Chen
J Neuroinflammation, 2019-10-25;16(1):189.
Species: Mouse
Sample Types: Tissue Homogenates
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Inactivation of MTOR promotes autophagy-mediated epithelial injury in particulate matter-induced airway inflammation
Authors: YF Wu, ZY Li, LL Dong, WJ Li, YP Wu, J Wang, HP Chen, HW Liu, M Li, CL Jin, HQ Huang, SM Ying, W Li, HH Shen, ZH Chen
Autophagy, 2019-06-16;0(0):1-16.
Species: Mouse
Sample Types: BALF
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Role of PM2.5 in the development and progression of COPD and its mechanisms
Authors: J Zhao, M Li, Z Wang, J Chen, J Zhao, Y Xu, X Wei, J Wang, J Xie
Respir. Res., 2019-06-13;20(1):120.
Species: Mouse
Sample Types: BALF
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Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust
Authors: KJ Warren, JD Dickinson, AJ Nelson, TA Wyatt, DJ Romberger, JA Poole
Respir. Res., 2019-03-07;20(1):51.
Species: Mouse
Sample Types: BALF
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Melatonin Inhibits Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Cultured Mouse Mammary Tissue
Authors: GM Yu, W Tan
Mediators Inflamm., 2019-02-12;2019(0):8597159.
Species: Mouse
Sample Types: Cell Culture Supernates
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Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis
Authors: N Saito, J Araya, S Ito, K Tsubouchi, S Minagawa, H Hara, A Ito, T Nakano, Y Hosaka, A Ichikawa, T Kadota, M Yoshida, Y Fujita, H Utsumi, Y Kurita, K Kobayashi, M Hashimoto, H Wakui, T Numata, Y Kaneko, H Asano, M Odaka, T Ohtsuka, T Morikawa, K Nakayama, K Kuwano
J. Immunol., 2019-01-28;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Costunolide alleviates HKSA-induced acute lung injury via inhibition of macrophage activation
Authors: YT Chen, Y Du, B Zhao, LX Gan, KK Yu, L Sun, J Wang, F Qian
Acta Pharmacol. Sin., 2019-01-15;0(0):.
Species: Mouse
Sample Types: BALF
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Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury
Authors: J Lou, Y Hu, MD Wu, LQ Che, YF Wu, Y Zhao, BP Tian, ZQ Bao, C Zhu, YP Wu, LL He, CX Bai, J Zhou, SM Ying, W Li, ZH Chen, DX Chen, A Dorling, HH Shen
Acta Pharmacol. Sin., 2018-11-16;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
Authors: M Taki, K Abiko, T Baba, J Hamanishi, K Yamaguchi, R Murakami, K Yamanoi, N Horikawa, Y Hosoe, E Nakamura, A Sugiyama, M Mandai, I Konishi, N Matsumura
Nat Commun, 2018-04-27;9(1):1685.
Species: Mouse
Sample Types: Serum
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andEfficacy of a Novel and Long Acting Fungicidal Azole, PC1244 onInfection
Authors: T Colley, G Sehra, A Chowdhary, A Alanio, SL Kelly, Y Kizawa, D Armstrong-, MC Fisher, AGS Warrilow, JE Parker, DE Kelly, G Kimura, Y Nishimoto, M Sunose, S Onions, D Crepin, F Lagasse, M Crittall, J Shannon, M McConville, J King-Under, A Naylor, S Bretagne, J Murray, K Ito, P Strong, G Rapeport
Antimicrob. Agents Chemother., 2018-04-26;0(0):.
Species: Mouse
Sample Types: BALF
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PAR2 (Protease-Activated Receptor 2) Deficiency Attenuates Atherosclerosis in Mice
Authors: SM Jones, A Mann, K Conrad, K Saum, DE Hall, LM McKinney, N Robbins, J Thompson, AD Peairs, E Camerer, KJ Rayner, M Tranter, N Mackman, AP Owens
Arterioscler. Thromb. Vasc. Biol., 2018-03-29;0(0):.
Species: Mouse
Sample Types: Plasma
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Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD
Authors: Z Zeng, M Li, J Chen, Q Li, Q Ning, J Zhao, Y Xu, J Xie, J Yu
Int J Chron Obstruct Pulmon Dis, 2018-02-28;13(0):703-715.
Species: Mouse
Sample Types: BALF
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Immunization with Pseudomonas aeruginosa outer membrane vesicles stimulates protective immunity in mice
Authors: X Zhang, F Yang, J Zou, W Wu, H Jing, Q Gou, H Li, J Gu, Q Zou, J Zhang
Vaccine, 2018-02-14;36(8):1047-1054.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA Capture -
Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome
Authors: MC Okondo, SD Rao, CY Taabazuing, AJ Chui, SE Poplawski, DC Johnson, DA Bachovchin
Cell Chem Biol, 2018-01-27;0(0):.
Species: Mouse
Sample Types: Serum
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In vivo biomarker analysis of intranasally dosed PC945, a novel antifungal triazole, on Aspergillus fumigatus infection in immunocompromised mice
Authors: G Kimura, T Nakaoki, T Colley, G Rapeport, P Strong, K Ito, Y Kizawa
Antimicrob. Agents Chemother., 2017-08-24;0(0):.
Species: Mouse
Sample Types: BALF
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Upregulation of SOCS3 in lung CD4+ T cells in a mouse model of chronic PA lung infection and suppression of Th17?mediated neutrophil recruitment in exogenous SOCS3 transfer in vitro
Authors: FM Ding, RM Liao, YQ Chen, GG Xie, PY Zhang, P Shao, M Zhang
Mol Med Rep, 2017-05-25;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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CXCL1 is critical for pre-metastatic niche formation and metastasis in colorectal cancer
Authors: D Wang, H Sun, J Wei, B Cen, RN DuBois
Cancer Res., 2017-04-28;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Cigarette Smoke Impairs A2A Adenosine Receptor Mediated Wound Repair through Up-regulation of Duox-1 Expression
Authors: Z Tian, H Zhang, J Dixon, N Traphagen, TA Wyatt, K Kharbanda, S Simet Chad, N Kolliputi, DS Allen-Gips
Sci Rep, 2017-03-24;7(0):44405.
Species: Mouse
Sample Types: BALF
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Malondialdehyde-acetaldehyde (MAA) adducted surfactant protein induced lung inflammation is mediated through scavenger receptor a (SR-A1)
Authors: M Sapkota, JM DeVasure, KK Kharbanda, TA Wyatt
Respir. Res, 2017-02-13;18(1):36.
Species: Mouse
Sample Types: BALF
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GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
Nat Commun, 2016-12-16;7(0):13796.
Species: Mouse
Sample Types: Cell Culture Supernates
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C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia
PLoS Pathog, 2016-12-06;12(12):e1006038.
Species: Mouse
Sample Types: Tissue Homogenates
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Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury
PLoS ONE, 2016-12-01;11(12):e0166770.
Species: Mouse
Sample Types: Tissue Homogenates
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Extracellular Superoxide Dismutase Enhances the Recruitment of Immature Neutrophils to the Liver
Infect Immun, 2016-11-18;0(0):.
Species: Mouse
Sample Types: Serum
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The Phosphocarrier Protein HPr Contributes to Meningococcal Survival during Infection
PLoS ONE, 2016-09-21;11(9):e0162434.
Species: Mouse
Sample Types: Peritoneal Fluid
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CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention
Authors: Daniel Hsu
Infect Immun, 2016-08-19;0(0):.
Species: Mouse
Sample Types: BALF
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Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
PLoS ONE, 2016-08-01;11(8):e0158735.
Species: Mouse
Sample Types: BALF
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CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin
Eur J Immunol, 2016-06-08;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression
Authors: L Seifert, G Werba, S Tiwari, NN Giao Ly, S Alothman, D Alqunaibit, A Avanzi, R Barilla, D Daley, SH Greco, A Torres-Her, M Pergamo, A Ochi, CP Zambirinis, M Pansari, M Rendon, D Tippens, M Hundeyin, VR Mani, C Hajdu, D Engle, G Miller
Nature, 2016-04-06;532(7598):245-9.
Species: Mouse
Sample Types: Tissue Homogenates
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DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways.
Authors: Chang S, Linderholm A, Harper R
PLoS ONE, 2015-07-06;10(7):e0131810.
Species: Mouse
Sample Types: BALF
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Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
Authors: Charolidi N, Schilling T, Eder C
PLoS ONE, 2015-05-26;10(5):e0128463.
Species: Mouse
Sample Types: Cell Culture Supernates
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The C-terminal disulfide bonds of Helicobacter pylori GroES are critical for IL-8 secretion via the TLR4-dependent pathway in gastric epithelial cells.
Authors: Su Y, Yang J, Lee H, Sheu F, Hsu C, Lin S, Chow L
J Immunol, 2015-03-13;194(8):3997-4007.
Species: Human
Sample Types: Cell Culture Supernates
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IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells.
Authors: Besnard A, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw T, Couper K, Ryffel B, Liew F
PLoS Pathog, 2015-02-06;11(2):e1004607.
Species: Mouse
Sample Types: Serum
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Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile.
Authors: Cowardin C, Kuehne S, Buonomo E, Marie C, Minton N, Petri W
MBio, 2015-01-27;6(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Protective effect of a germline, IL-17-neutralizing antibody in murine models of autoimmune inflammatory disease.
Authors: Dallenbach K, Maurer P, Rohn T, Zabel F, Kopf M, Bachmann M
Eur J Immunol, 2015-01-23;45(4):1238-47.
Species: Mouse
Sample Types: Serum
-
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.
Authors: Schliehe C, Flynn E, Vilagos B, Richson U, Swaminathan S, Bosnjak B, Bauer L, Kandasamy R, Griesshammer I, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett A, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein M, Symer D, Aderem A, Bergthaler A
Nat Immunol, 2014-11-24;16(1):67-74.
Species: Mouse
Sample Types: Cell Lysates
-
Role of TLR5 and flagella in bacillus intraocular infection.
Authors: Parkunan, Salai Ma, Astley, Roger, Callegan, Michelle
PLoS ONE, 2014-06-24;9(6):e100543.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.
Authors: Wu L, Ong S, Talor M, Barin J, Baldeviano G, Kass D, Bedja D, Zhang H, Sheikh A, Margolick J, Iwakura Y, Rose N, Cihakova D
J Exp Med, 2014-06-16;211(7):1449-64.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Nuclear factor of activated T cells regulates neutrophil recruitment, systemic inflammation, and T-cell dysfunction in abdominal sepsis.
Authors: Zhang S, Luo L, Wang Y, Gomez M, Thorlacius H
Infect Immun, 2014-05-27;82(8):3275-88.
Species: Mouse
Sample Types: Tissue Homogenates
-
Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2.
Authors: Tancevski I, Nairz M, Duwensee K, Auer K, Schroll A, Heim C, Feistritzer C, Hoefer J, Gerner R, Moschen A, Heller I, Pallweber P, Li X, Theurl M, Demetz E, Wolf A, Wolf D, Eller P, Ritsch A, Weiss G
EMBO Mol Med, 2014-04-06;6(6):810-20.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
Authors: Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X
J Biol Chem, 2014-03-13;289(16):11522-35.
Species: Mouse
Sample Types: Whole Cells
-
Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers.
Authors: Mercado, Nicolas, Kizawa, Yasuo, Ueda, Keitaro, Xiong, Yeping, Kimura, Genki, Moses, Audric, Curtis, Jonathan, Ito, Kazuhiro, Barnes, Peter J
PLoS ONE, 2014-02-05;9(2):e88168.
Species: Mouse
Sample Types: BALF
-
Pseudomonas aeruginosa MucD protease mediates keratitis by inhibiting neutrophil recruitment and promoting bacterial survival.
Authors: Mochizuki Y, Suzuki T, Oka N, Zhang Y, Hayashi Y, Hayashi N, Gotoh N, Ohashi Y
Invest Ophthalmol Vis Sci, 2014-01-09;55(1):240-6.
Species: Mouse
Sample Types: Tissue Homogenates
-
Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.
Authors: Snowden J, Beaver M, Beenken K, Smeltzer M, Horswill A, Kielian T
PLoS ONE, 2013-12-30;8(12):e84089.
Species: Mouse
Sample Types: Tissue Homogenates
-
Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.
Authors: Vergadi, Eleni, Vaporidi, Katerina, Theodorakis, Emmanuel, Doxaki, Christin, Lagoudaki, Eleni, Ieronymaki, Elefther, Alexaki, Vassilia, Helms, Mike, Kondili, Eumorfia, Soennichsen, Birte, Stathopoulos, Efstathi, Margioris, Andrew N, Georgopoulos, Dimitrio, Tsatsanis, Christos
J Immunol, 2013-11-25;192(1):394-406.
Species: Mouse
Sample Types: BALF
-
Helical carbon nanotubes enhance the early immune response and inhibit macrophage-mediated phagocytosis of Pseudomonas aeruginosa.
Authors: Walling, Brent E, Kuang, Zhizhou, Hao, Yonghua, Estrada, David, Wood, Joshua D, Lian, Feifei, Miller, Lou Ann, Shah, Amish B, Jeffries, Jayme L, Haasch, Richard, Lyding, Joseph W, Pop, Eric, Lau, Gee W
PLoS ONE, 2013-11-18;8(11):e80283.
Species: Mouse
Sample Types: BALF
-
CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-beta.
Authors: Jablonska J, Wu C, Andzinski L, Leschner S, Weiss S
Int J Cancer, 2013-10-31;134(6):1346-58.
Species: Mouse
Sample Types: Tissue Homogenates
-
CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model.
Authors: Besnard A, Struyf S, Guabiraba R, Fauconnier L, Rouxel N, Proost P, Uyttenhove C, Van Snick J, Couillin I, Ryffel B
J Leukoc Biol, 2013-08-23;94(6):1317-23.
Species: Mouse
Sample Types: Tissue Homogenates
-
A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis.
Authors: Hoehlig, Kai, Maasch, Christia, Shushakova, Nelli, Buchner, Klaus, Huber-Lang, Markus, Purschke, Werner G, Vater, Axel, Klussmann, Sven
Mol Ther, 2013-07-26;21(12):2236-46.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Endothelial cell peroxisome proliferator-activated receptor gamma reduces endotoxemic pulmonary inflammation and injury.
Authors: Reddy A, Lakshmi S, Kleinhenz J, Sutliff R, Hart C, Reddy R
J Immunol, 2012-10-26;189(11):5411-20.
Species: Mouse
Sample Types: BALF
-
Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice.
Authors: Aeffner F, Davis I
PLoS ONE, 2012-10-02;7(10):e46660.
Species: Mouse
Sample Types: BALF
-
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Authors: Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam T, Leypoldt F, Simova O, Thom V, Friese M, Prinz I, Holscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T
Blood, 2012-09-13;120(18):3793-802.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner.
Blood, 2012-07-17;120(13):2600-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Inhalative vs. systemic IL-10 administration: differences in the systemic inflammatory response and end-organ inflammation following hemorrhagic shock.
Authors: Pfeifer R, Lichte P, Schreiber H, Sellei R, Schmidt J, Dombroski D, Pape H, Kobbe P
Cytokine, 2012-06-21;60(1):266-70.
Species: Mouse
Sample Types: Serum
-
Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease.
Authors: Chantrathammachart P, Mackman N, Sparkenbaugh E
Blood, 2012-06-01;120(3):636-46.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.
Authors: Gais P, Reim D, Jusek G, Rossmann-Bloeck T, Weighardt H, Pfeffer K, Altmayr F, Janssen KP, Holzmann B
J. Immunol., 2012-05-14;188(12):5833-7.
Species: Mouse
Sample Types: Plasma
-
CRTH2 Is A Critical Regulator of Neutrophil Migration and Resistance to Polymicrobial Sepsis.
Authors: Ishii M, Asano K, Namkoong H, Tasaka S, Mizoguchi K, Asami T, Kamata H, Kimizuka Y, Fujiwara H, Funatsu Y, Kagawa S, Miyata J, Ishii K, Nakamura M, Hirai H, Nagata K, Kunkel SL, Hasegawa N, Betsuyaku T
J. Immunol., 2012-04-27;188(11):5655-64.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
The axonal guidance receptor neogenin promotes acute inflammation.
Authors: Konig K, Gatidou D, Granja T, Meier J, Rosenberger P, Mirakaj V
PLoS ONE, 2012-03-06;7(3):e32145.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis.
Authors: Roy M, Richard JF, Dumas A, Vallieres L
J Neuroinflammation, 2012-01-23;9(0):18.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012-01-18;7(1):e30005.
Species: Mouse
Sample Types: Tissue Homogenates
-
ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia.
Authors: Bondue B, Vosters O, de Nadai P, Glineur S, De Henau O, Luangsay S, Van Gool F, Communi D, De Vuyst P, Desmecht D, Parmentier M
PLoS Pathog., 2011-11-03;7(11):e1002358.
Species: Mouse
Sample Types: BALF
-
Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-alpha stimulated gene/protein 6.
Authors: Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH, Prockop DJ
Stem Cells, 2011-10-01;29(10):1572-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II.
Authors: Burton VJ, Holmes AM, Ciuclan LI
Blood, 2011-09-07;118(17):4750-8.
Species: Mouse
Sample Types: Plasma
-
Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response.
Authors: Reim D, Rossmann-Bloeck T, Jusek G, Prazeres da Costa O, Holzmann B
J. Leukoc. Biol., 2011-05-31;90(3):613-20.
Species: Mouse
Sample Types: Plasma
-
Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
Authors: Koroskenyi K, Duro E, Pallai A, Sarang Z, Kloor D, Ucker DS, Beceiro S, Castrillo A, Chawla A, Ledent CA, Fésüs L, Szondy Z
J. Immunol., 2011-05-18;186(12):7144-55.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
Authors: Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
J. Lipid Res., 2011-04-26;52(7):1307-18.
Species: Mouse
Sample Types: Air Pouch Exudate
-
CCL20, gammadelta T cells, and IL-22 in corneal epithelial healing.
Authors: Li Z, Burns AR, Miller SB, Smith CW
FASEB J., 2011-04-25;25(8):2659-68.
Species: Mouse
Sample Types: Tissue Homogenates
-
The Role of ChemR23 in the Induction and Resolution of Cigarette Smoke-Induced Inflammation.
Authors: Demoor T, Bracke KR, Dupont LL
J. Immunol., 2011-03-23;186(9):5457-67.
Species: Mouse
Sample Types: BALF
-
Overexpression of sICAM-1 in the Alveolar Epithelial Space Results in an Exaggerated Inflammatory Response and Early Death in Gram Negative Pneumonia.
Authors: Mendez MP, Monroy YK, Du M
Respir. Res., 2011-01-19;12(1):12.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
J. Immunol., 2010-11-22;186(1):556-62.
Species: Mouse
Sample Types: BALF
-
S100A8/A9 is not involved in host defense against murine urinary tract infection.
Authors: Dessing MC, Butter LM, Teske GJ
PLoS ONE, 2010-10-14;5(10):e13394.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-22 induces an acute-phase response.
Authors: Liang SC, Nickerson-Nutter C, Pittman DD
J. Immunol., 2010-09-24;185(9):5531-8.
Species: Mouse
Sample Types: Serum
-
Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
Authors: Ito H, Hoshi M, Ohtaki H, Taguchi A, Ando K, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M
J. Immunol., 2010-09-15;185(8):4554-60.
Species: Mouse
Sample Types: Serum
-
TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice.
Authors: Tang H, Pang S, Wang M
J. Immunol., 2010-07-14;185(4):2563-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
Authors: Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch J, Schirmacher P, Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Hasler R, Becker C, Neurath MF, Reiss K, Saftig P, Scheller J, Rose-John S
J. Exp. Med., 2010-07-05;207(8):1617-24.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia.
Authors: Schabbauer G, Matt U, Gunzl P, Warszawska J, Furtner T, Hainzl E, Elbau I, Mesteri I, Doninger B, Binder BR, Knapp S
J. Immunol., 2010-05-26;185(1):468-76.
Species: Mouse
Sample Types: Tissue Homogenates
-
Regulation of corneal inflammation by neutrophil-dependent cleavage of keratan sulfate proteoglycans as a model for breakdown of the chemokine gradient.
Authors: Carlson EC, Sun Y, Auletta J
J. Leukoc. Biol., 2010-05-21;88(3):517-22.
Species: Mouse
Sample Types: Aqueous Humor
-
TLR4 is a negative regulator in noninfectious lung inflammation.
Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
J. Immunol., 2010-03-31;184(9):5308-14.
Species: Mouse
Sample Types: BALF
-
Chemokine homeostasis vs. chemokine presentation during severe acute lung injury: the other side of the Duffy antigen receptor for chemokines.
Authors: Zarbock A, Bishop J, Muller H, Schmolke M, Buschmann K, Van Aken H, Singbartl K
Am. J. Physiol. Lung Cell Mol. Physiol., 2010-01-08;298(3):L462-71.
Species: Mouse
Sample Types: Plasma
-
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2009-12-29;49(3):256-63.
Species: Mouse
Sample Types: BALF
-
Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
Authors: Zhu M, Hug C, Kasahara DI
Am. J. Respir. Cell Mol. Biol., 2009-11-13;43(4):487-97.
Species: Mouse
Sample Types: BALF
-
House dust mite induces direct airway inflammation in vivo: implications for future disease therapy?
Authors: De Alba J, Raemdonck K, Dekkak A, Collins M, Wong S, Nials AT, Knowles RG, Belvisi MG, Birrell MA
Eur. Respir. J., 2009-10-19;35(6):1377-87.
Species: Rat
Sample Types: BALF
-
Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
Am. J. Respir. Crit. Care Med., 2009-09-17;180(12):1208-17.
Species: Mouse
Sample Types: BALF
-
Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).
Authors: Zarbock A, Distasi MR, Smith E, Sanders JM, Kronke G, Harry BL, von Vietinghoff S, Buscher K, Nadler JL, Ley K
J. Immunol., 2009-09-14;183(7):4715-22.
Species: Mouse
Sample Types: BALF
-
Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
Authors: Pini M, Fantuzzi G
J. Leukoc. Biol., 2009-09-10;87(1):51-8.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease.
Authors: Schneider DJ, Lindsay JC, Zhou Y, Molina JG, Blackburn MR
FASEB J., 2009-08-31;24(1):70-80.
Species: Mouse
Sample Types: Tissue Homogenates
-
TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
Authors: Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, Henson PM, Janssen WJ
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-07-31;297(4):L586-95.
Species: Mouse
Sample Types: BALF
-
Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
Authors: Hayashida K, Parks WC, Park PW
Blood, 2009-07-28;114(14):3033-43.
Species: Mouse
Sample Types: Serum
-
MCP-1 antibody treatment enhances damage and impedes repair of the alveolar epithelium in influenza pneumonitis.
Authors: Narasaraju T, Ng HH, Phoon MC
Am. J. Respir. Cell Mol. Biol., 2009-07-17;42(6):732-43.
Species: Mouse
Sample Types: Serum
-
TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
Authors: Thaxton JE, Romero R, Sharma S
J. Immunol., 2009-06-26;183(2):1144-54.
Species: Mouse
Sample Types: Serum
-
Endotoxin augmented antigen-induced Th1 cell trafficking amplifies airway neutrophilic inflammation.
Authors: Mikhak Z, Farsidjani A, Luster AD
J. Immunol., 2009-06-15;182(12):7946-56.
Species: Mouse
Sample Types: BALF
-
IL-17 receptor signaling is required to control polymicrobial sepsis.
Authors: Freitas A, Alves-Filho JC, Victoni T, Secher T, Lemos HP, Sonego F, Cunha FQ, Ryffel B
J. Immunol., 2009-06-15;182(12):7846-54.
Species: Mouse
Sample Types: Tissue Secretion
-
Keratinocyte-derived chemokine in obesity: expression, regulation, and role in adipose macrophage infiltration and glucose homeostasis.
Authors: Neels JG, Badeanlou L, Hester KD, Samad F
J. Biol. Chem., 2009-06-03;284(31):20692-8.
Species: Mouse
Sample Types: Serum
-
TLR2 deficiency leads to increased Th17 infiltrates in experimental brain abscesses.
Authors: Nichols JR, Aldrich AL, Mariani MM, Vidlak D, Esen N, Kielian T
J. Immunol., 2009-06-01;182(11):7119-30.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Urokinase plasminogen activator receptor-deficient mice demonstrate reduced hyperoxia-induced lung injury.
Authors: van Zoelen MA, Florquin S, de Beer R, Pater JM, Verstege MI, Meijers JC, van der Poll T
Am. J. Pathol., 2009-05-12;174(6):2182-9.
Species: Mouse
Sample Types: BALF
-
LPS induces GROalpha chemokine production via NF-kappaB in oral fibroblasts.
Authors: Jonsson D, Amisten S, Bratthall G, Holm A, Nilsson BO
Inflamm. Res., 2009-05-09;58(11):791-6.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.
Authors: Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR
Am. J. Respir. Crit. Care Med., 2009-04-02;180(3):247-56.
Species: Mouse
Sample Types: BALF
-
A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
Int. Immunol., 2008-12-09;21(1):81-93.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses.
Authors: Zhou W, Newcomb DC, Moore ML, Goleniewska K, O'Neal JF, Peebles RS
J. Immunol., 2008-10-15;181(8):5360-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2008-09-17;75(1):52-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
Authors: Leoni G, Patel HB, Sampaio AL, Gavins FN, Murray JF, Grieco P, Getting SJ, Perretti M
FASEB J., 2008-08-29;22(12):4228-38.
Species: Mouse
Sample Types: Plasma
-
Airway house dust extract exposures modify allergen-induced airway hypersensitivity responses by TLR4-dependent and independent pathways.
Authors: Lam D, Ng N, Lee S, Batzer G, Horner AA
J. Immunol., 2008-08-15;181(4):2925-32.
Species: Mouse
Sample Types: BALF
-
Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro.
Authors: Lin M, Jackson P, Tester AM, Diaconu E, Overall CM, Blalock JE, Pearlman E
Am. J. Pathol., 2008-06-13;173(1):144-53.
Species: Mouse
Sample Types: Tissue Homogenates
-
Chemical sympathectomy increases susceptibility to ocular herpes simplex virus type 1 infection.
Authors: Templeton A, Nguyen G, Ash JD, Straub RH, Carr DJ
J. Neuroimmunol., 2008-05-20;197(1):37-46.
Species: Mouse
Sample Types: Tissue Homogenates
-
The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke.
Authors: Le Quement C, Guenon I, Gillon JY, Valenca S, Cayron-Elizondo V, Lagente V, Boichot E
Br. J. Pharmacol., 2008-05-19;154(6):1206-15.
Species: Mouse
Sample Types: BALF
-
Aspergillus fumigatus stimulates leukocyte adhesion molecules and cytokine production by endothelial cells in vitro and during invasive pulmonary disease.
Authors: Chiang LY, Sheppard DC, Gravelat FN, Patterson TF, Filler SG
Infect. Immun., 2008-05-19;76(8):3429-38.
Species: Mouse
Sample Types: Tissue Homogenates
-
Functional Th1 cells are required for surgical adhesion formation in a murine model.
Authors: Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW
J. Immunol., 2008-05-15;180(10):6970-6.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Synthetic chemerin-derived peptides suppress inflammation through ChemR23.
Authors: Cash JL, Hart R, Russ A, Dixon JP, Colledge WH, Doran J, Hendrick AG, Carlton MB, Greaves DR
J. Exp. Med., 2008-04-07;205(4):767-75.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Neutrophil chemokines KC and macrophage-inflammatory protein-2 are newly synthesized by tissue macrophages using distinct TLR signaling pathways.
Authors: De Filippo K, Henderson RB, Laschinger M, Hogg N
J. Immunol., 2008-03-15;180(6):4308-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients.
Authors: Swee M, Wilson CL, Wang Y, McGuire JK, Parks WC
J. Leukoc. Biol., 2008-03-11;83(6):1404-12.
Species: Mouse
Sample Types: Lavage Fluid
-
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
Nat. Med., 2008-02-03;14(2):199-204.
Species: Mouse
Sample Types: BALF
-
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
J. Immunol., 2008-01-01;180(1):609-17.
Species: Mouse
Sample Types: Tissue Secretion
-
The role of macrophage migration inhibitory factor in the cascade of events leading to reperfusion-induced inflammatory injury and lethality.
Authors: Amaral FA, Fagundes CT, Guabiraba R, Vieira AT, Souza AL, Russo RC, Soares MP, Teixeira MM, Souza DG
Am. J. Pathol., 2007-11-30;171(6):1887-93.
Species: Mouse
Sample Types: Serum
-
Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo.
Authors: Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, O'Connell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL
J. Immunol., 2007-11-15;179(10):6933-42.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4498-508.
Species: Mouse
Sample Types: Tissue Homogenates
-
Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice.
Authors: Kagari T, Tanaka D, Doi H, Iwakura Y, Shimozato T
Eur. J. Immunol., 2007-10-01;37(10):2753-63.
Species: Mouse
Sample Types: Plasma
-
The Duffy antigen receptor for chemokines in acute renal failure: A facilitator of renal chemokine presentation.
Authors: Zarbock A, Schmolke M, Bockhorn SG, Scharte M, Buschmann K, Ley K, Singbartl K
Crit. Care Med., 2007-09-01;35(9):2156-63.
Species: Mouse
Sample Types: Plasma
-
Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
Crit. Care Med., 2007-08-01;35(8):1955-60.
Species: Mouse
Sample Types: Plasma
-
Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
Authors: Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, Repici A, Arena V, Malesci A, Panes J, Grinnell BW, Danese S
J. Clin. Invest., 2007-07-01;117(7):1951-60.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
Am. J. Physiol. Lung Cell Mol. Physiol., 2007-06-01;293(2):L491-6.
Species: Mouse
Sample Types: Serum
-
Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
Authors: Nguyen M, Pace AJ, Koller BH
J. Exp. Med., 2007-05-21;204(6):1383-93.
Species: Mouse
Sample Types: Tissue Homogenates
-
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
J. Immunol., 2007-05-15;178(10):6252-8.
Species: Mouse
Sample Types: Tissue Homogenates
-
Airway epithelial STAT3 is required for allergic inflammation in a murine model of asthma.
Authors: Simeone-Penney MC, Severgnini M, Tu P, Homer RJ, Mariani TJ, Cohn L, Simon AR
J. Immunol., 2007-05-15;178(10):6191-9.
Species: Mouse
Sample Types: BALF
-
CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease.
Authors: Hollingsworth JW, Li Z, Brass DM, Garantziotis S, Timberlake SH, Kim A, Hossain I, Savani RC, Schwartz DA
Am. J. Respir. Cell Mol. Biol., 2007-04-19;37(2):248-53.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice.
Authors: Wilson MR, Goddard ME, O&apos;Dea KP, O'Dea KP, Choudhury S, Takata M
Am. J. Physiol. Lung Cell Mol. Physiol., 2007-04-13;293(1):L60-8.
Species: Mouse
Sample Types: BALF
-
Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).
Authors: Gutierrez-Fernandez A, Inada M, Balbin M, Fueyo A, Pitiot AS, Astudillo A, Hirose K, Hirata M, Shapiro SD, Noel A, Werb Z, Krane SM, Lopez-Otin C, Puente XS
FASEB J., 2007-03-28;21(10):2580-91.
Species: Mouse
Sample Types: Tissue Homogenates
-
Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
Am. J. Pathol., 2007-03-01;170(3):1003-17.
Species: Mouse
Sample Types: Tissue Homogenates
-
The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
Life Sci., 2007-02-03;80(20):1821-31.
Species: Mouse
Sample Types: BALF
-
C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
Authors: Thurman JM, Lenderink AM, Royer PA, Coleman KE, Zhou J, Lambris JD, Nemenoff RA, Quigg RJ, Holers VM
J. Immunol., 2007-02-01;178(3):1819-28.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cathepsin-G interferes with clearance of Pseudomonas aeruginosa from mouse lungs.
Authors: Sedor J, Hogue L, Akers K, Boslaugh S, Schreiber J, Ferkol T
Pediatr. Res., 2007-01-01;61(1):26-31.
Species: Mouse
Sample Types: BALF
-
Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection.
Authors: Gregory AD, Hogue LA, Ferkol TW, Link DC
Blood, 2006-12-21;109(8):3235-43.
Species: Mouse
Sample Types: Epithelial Fluid
-
Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.
Authors: Nenan S, Lagente V, Planquois JM, Hitier S, Berna P, Bertrand CP, Boichot E
Eur. J. Pharmacol., 2006-12-12;559(1):75-81.
Species: Mouse
Sample Types: Tissue Homogenates
-
Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice.
Authors: Bubeck SS, Cantwell AM, Dube PH
Infect. Immun., 2006-11-13;75(2):697-705.
Species: Mouse
Sample Types: BALF
-
Altered postnatal lung development in C3H/HeJ mice.
Authors: Sampath V, Davis K, Senft AP, Richardson TR, Kitzmiller JA, Berclaz PY, Korfhagen TR
Pediatr. Res., 2006-10-25;60(6):663-8.
Species: Mouse
Sample Types: Tissue Homogenates
-
Type I IFN modulates host defense and late hyperinflammation in septic peritonitis.
Authors: Weighardt H, Kaiser-Moore S, Schlautkotter S, Rossmann-Bloeck T, Schleicher U, Bogdan C, Holzmann B
J. Immunol., 2006-10-15;177(8):5623-30.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2006-10-11;70(11):1942-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils.
Authors: Rose DM, Sydlaske AD, Agha-Babakhani A, Johnson K, Terkeltaub R
Arthritis Rheum., 2006-10-01;54(10):3363-71.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
Int. Immunol., 2006-09-11;18(11):1531-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
[D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse).
Authors: Getting SJ, Lam CW, Leoni G, Gavins FN, Grieco P, Perretti M
Mol. Pharmacol., 2006-09-07;70(6):1850-5.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
J. Biol. Chem., 2006-08-04;281(39):28794-801.
Species: Mouse
Sample Types: Plasma
-
The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
Authors: Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006-06-09;291(4):L677-82.
Species: Mouse
Sample Types: BALF
-
Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung.
Authors: Andre E, Stoeger T, Takenaka S, Bahnweg M, Ritter B, Karg E, Lentner B, Reinhard C, Schulz H, Wjst M
Eur. Respir. J., 2006-04-26;28(2):275-85.
Species: Mouse
Sample Types: BALF
-
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
Cancer Res., 2006-04-15;66(8):4198-207.
Species: Mouse
Sample Types: BALF, Tissue Homogenates
-
Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
Authors: Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W
Eur. J. Immunol., 2005-09-01;35(9):2573-82.
Species: Mouse
Sample Types: Serum
-
Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation.
Authors: Gueders MM, Balbin M, Rocks N, Foidart JM, Gosset P, Louis R, Shapiro S, Lopez-Otin C, Noel A, Cataldo DD
J. Immunol., 2005-08-15;175(4):2589-97.
Species: Mouse
Sample Types: BALF
-
The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.
Authors: Jensen KK, Manfra DJ, Grisotto MG, Martin AP, Vassileva G, Kelley K, Schwartz TW, Lira SA
J. Immunol., 2005-03-15;174(6):3686-94.
Species: Mouse
Sample Types: Tissue Homogenates
-
Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
Authors: Weijer S, Florquin S, van der Poll T
Shock, 2005-01-01;23(1):54-8.
Species: Mouse
Sample Types: Peritoneal Fluid
-
The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
Authors: Cotena A, Platt N
J. Immunol., 2004-11-15;173(10):6427-32.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The role of gammadelta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury.
Authors: Toth B, Alexander M, Daniel T, Hubbard WJ, Schwacha MG
J. Leukoc. Biol., 2004-06-14;76(3):545-52.
Species: Mouse
Sample Types: Plasma
-
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
J. Exp. Med., 2004-05-17;199(10):1355-65.
Species: Mouse
Sample Types: Serum
-
Combinations of cytokines promote survival of mice and limit acute radiation damage in concert with amelioration of vascular damage.
Authors: Van der Meeren A, Mouthon MA, Vandamme M, Squiban C, Aigueperse J
Radiat. Res., 2004-05-01;161(5):549-59.
Species: Mouse
Sample Types:
-
Circulating CXC-chemokine concentrations in a murine intestinal ischemia-reperfusion model.
Authors: Maheshwari A, Christensen RD, Calhoun DA
Fetal Pediatr Pathol, 2004-03-01;23(2):145-57.
Species: Mouse
Sample Types: Serum
-
Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
Blood, 2003-10-30;103(5):1702-9.
Species: Mouse
Sample Types: BALF
-
Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
Authors: McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N
J. Clin. Invest., 2003-08-01;112(4):598-607.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Enhanced susceptibility to end-organ disease in the lupus-facilitating NZW mouse strain.
Authors: Xie C, Zhou XJ, Liu X, Mohan C
Arthritis Rheum., 2003-04-01;48(4):1080-92.
Species: Mouse
Sample Types: Urine
-
Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
Infect. Immun., 2003-04-01;71(4):2276-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor.
Authors: Getting SJ, Christian HC, Lam CW, Gavins FN, Flower RJ, Schioth HB, Perretti M
J. Immunol., 2003-03-15;170(6):3323-30.
Species: Mouse
Sample Types: Peritoneal Fluid
-
IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
J. Immunol., 2003-02-15;170(4):2106-12.
Species: Mouse
Sample Types: BALF
-
Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
Authors: Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS
J. Immunol., 2003-01-15;170(2):1091-8.
Species: Mouse
Sample Types: BALF
-
Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation.
Authors: Garcia-Ramallo E, Marques T, Prats N, Beleta J, Kunkel SL, Godessart N
J. Immunol., 2002-12-01;169(11):6467-73.
Species: Mouse
Sample Types: Air Pouch Exudate
-
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Authors: Weighardt H, Bê Ë„Æ%í, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
2002-09-15;169(6):2823-7.
Species: Mouse
Sample Types: Serum
-
The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice.
Authors: Fierer J, Swancutt MA, Heumann D, Golenbock D
J. Immunol., 2002-06-15;168(12):6396-403.
Species: Mouse
Sample Types: Interperitoneal Fluid
-
Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense.
Authors: Villa P, Saccani A, Sica A, Ghezzi P
J. Infect. Dis., 2002-04-01;185(8):1115-20.
Species: Mouse
Sample Types: Serum
-
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001-07-01;31(7):2104-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
Immunity, 2001-06-01;14(6):705-14.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
J. Immunol., 2001-01-15;166(2):1233-40.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
Authors: Medvedev AE, Kopydlowski KM, Vogel SN
J. Immunol., 2000-06-01;164(11):5564-74.
Species: Mouse
Sample Types: Cell Culture Supernates
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