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Mouse CXCR3 APC-conjugated Antibody

Catalog #: FAB1685A
7 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB1685A-025
FAB1685A-100
Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry.
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Product Details
Citations (7)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse CXCR3 APC-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse CXCR3.
Source
Monoclonal Rat IgG2A Clone # 220803
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
CHO Chinese hamster ovary cell line transfected with mouse CXCR3
Met1-Leu367
Accession # AAC40163
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of CXCR3 antibody in Mouse Splenocytes antibody by Flow Cytometry. View Larger

Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 PE-conjugated Monoclonal Antibody (Catalog # FAB4841P) and either (A) Rat Anti-Mouse CXCR3 APC-conjugated Monoclonal Antibody (Catalog # FAB1685A) or (B) Rat IgG2AAllophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CXCR3

CXCR3 is a G protein coupled chemokine receptor that binds the alpha chemokines MIG (CXCL9), IP-10 (CXCL10) and I-TAC (CXCL11). CXCR3 is expressed on activated T cells, B cells and NK cells.

Entrez Gene IDs
2833 (Human); 12766 (Mouse); 84475 (Rat)
Alternate Names
CD183 antigen; CD183; chemokine (C-X-C motif) receptor 3; chemokine (C-X-C) receptor 3; CKR-L2IP-10 receptor; CMKAR3; C-X-C chemokine receptor type 3; CXCR3; CXC-R3; CXCR-3; G protein-coupled receptor 9CD182; GPR9; GPR9Mig-R; Interferon-inducible protein 10 receptor; IP10 receptor; IP10-R; Mig receptor; MigR

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Citations for Mouse CXCR3 APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

7 Citations: Showing 1 - 7
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  1. Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints
    Authors: M. E. Mikucki, D. T. Fisher, J. Matsuzaki, J. J. Skitzki, N. B. Gaulin, J. B. Muhitch et al.
    Nature Communications
  2. Cryptococcus gattii infection dampens Th1 and Th17 responses by attenuating dendritic cell function and pulmonary chemokine expression in the immunocompetent hosts.
    Authors: Angkasekwinai P, Sringkarin N, Supasorn O, Fungkrajai M, Wang Y, Chayakulkeeree M, Ngamskulrungroj P, Angkasekwinai N, Pattanapanyasat K
    Infect Immun, 2014-06-30;82(9):3880-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.
    Authors: Mackay L, Rahimpour A, Ma J, Collins N, Stock A, Hafon M, Vega-Ramos J, Lauzurica P, Mueller S, Stefanovic T, Tscharke D, Heath W, Inouye M, Carbone F, Gebhardt T
    Nat Immunol, 2013-10-27;14(12):1294-301.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Early differentiated CD138(high) MHCII+ IgG+ plasma cells express CXCR3 and localize into inflamed kidneys of lupus mice.
    Authors: Lacotte S, Decossas M, Le Coz C, Brun S, Muller S, Dumortier H
    PLoS ONE, 2013-03-08;8(3):e58140.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation.
    Authors: Giegold O, Ogrissek N, Richter C, Schroder M, Herrero San Juan M, Pfeilschifter J, Radeke H
    J Immunol, 2013-02-27;190(7):3696-705.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. Chemokine receptor CXCR3 promotes growth of glioma.
    Authors: Liu C, Luo D, Reynolds BA
    Carcinogenesis, 2010-11-03;32(2):129-37.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  7. Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency.
    Authors: Miu J, Mitchell AJ, Muller M, Carter SL, Manders PM, McQuillan JA, Saunders BM, Ball HJ, Lu B, Campbell IL, Hunt NH
    J. Immunol., 2008-01-15;180(2):1217-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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