Mouse EMR4 (NP_631877) VersaClone cDNA

Catalog #: RDC0208 Datasheet / COA / SDS

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RDC0208

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Mouse EMR4 (NP_631877) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Mouse

Product Datasheets

Product Datasheet

COA

SDS

Background: EMR4

EMR4 cDNA encodes a predicted 689-amino acid protein containing two epidermal growth factor (EGF)-like modules, a mucin-like spacer domain, and a seven-transmembrane domain with a cytoplasmic tail. EMR4 was found to undergo proteolytic processing within the extracellular stalk region resulting in two protein subunits associated noncovalently as a heterodimer. It is predominantly expressed on resident macrophages. However, a much lower expression level was also detected in thioglycollate-elicited peritoneal neutrophils and bone marrow-derived dendritic cells. EMR4 is the first EGF-TM7 receptor known to mediate the cellular interaction between myeloid cells and B-cells.

Long Name

EGF-like Module Containing, Mucin-like, Hormone Receptor-like 4

Entrez Gene IDs

326342 (Human); 52614 (Mouse)

Alternate Names

egf-like module containing, mucin-like, hormone receptor-like 4 pseudogene; egf-like module containing, mucin-like, hormone receptor-like 4; Egf-tm7; EMR4; EMR4EGF-like module receptor 4; Fire; Gpr127; GPR127G-protein coupled receptor 127; G-protein coupled receptor PGR16; PGR16; PGR16G protein-coupled receptor 127

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