Mouse Fc epsilon RI alpha (NP_034314) VersaClone cDNA

Catalog #: RDC0950 Datasheet / COA / SDS

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RDC0950

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Mouse Fc epsilon RI alpha (NP_034314) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Mouse

Product Datasheets

Product Datasheet

COA

SDS

Background: Fc epsilon RI alpha

Fc epsilon RI alpha is a transmembrane protein that associates with beta and gamma subunits to form the high affinity IgE receptor on basophils and mast cells. Cellular activation by IgE/Fc epsilon RI crosslinking causes degranulation, releasing histamine, leukotrienes, prostaglandins, and other mediators of immediate type and late phase allergic reactions. Fc epsilon RI on human antigen presenting cells mediates uptake and processing of allergens for presentation by class II MHC. Fc epsilon RI expression on human DC and Langerhans cells is upregulated during allergic reactions (atopy) and correlates with serum IgE concentration.

Long Name

Fc epsilon Receptor I alpha

Entrez Gene IDs

2205 (Human); 14125 (Mouse); 25047 (Rat)

Alternate Names

Fc epsilon RI alpha; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; FCE1A; Fc-epsilon RI-alpha; FcepsilonRI alpha chain; FcepsilonRIalpha; FCER1A; FcERI; FceRIa; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; igE Fc receptor subunit alpha; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide