Mouse GFR alpha -4/GDNF R alpha -4 Antibody

Catalog #: AF1677
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF1677
AF1677-SP

All GFR alpha-4/GDNF R alpha-4 Antibodies

Product Details

Citations (1)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse GFR alpha -4/GDNF R alpha -4 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse GFR alpha ‑4/GDNF R alpha ‑4 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human GFR alpha -4 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse GFR alpha ‑4/GDNF R alpha ‑4
Asn24-Thr237
Accession # Q99JT2

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Immunohistochemistry

5-15 µg/mL

Perfusion fixed frozen sections of mouse brain (medulla)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: GFR alpha-4/GDNF R alpha-4

GFR alpha -4 is a GPI-linked cell surface protein that associates with the c-Ret transmembrane tyrosine kinase to form a functional receptor complex for the GDNF family ligand, persephin.

Long Name

Glial Cell line-derived Neurotrophic Factor Receptor alpha 4

Entrez Gene IDs

64096 (Human); 14588 (Mouse)

Alternate Names

GDNF family receptor alpha 4; GDNF family receptor alpha-4; GDNF R alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR alpha4; GFR alpha-4; GFR receptor alpha 4; GFRA4; GFRa-4; GFR-alpha-4; Persephin receptor

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

GDNF Family

Citation for Mouse GFR alpha -4/GDNF R alpha -4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Ablation of persephin receptor glial cell line-derived neurotrophic factor family receptor alpha4 impairs thyroid calcitonin production in young mice.
Authors: Lindfors PH, Lindahl M, Rossi J, Saarma M, Airaksinen MS
Endocrinology, 2006-02-23;147(5):2237-44.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr

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