Mouse GPR20 (NP_775541) VersaClone cDNA

Catalog #: RDC0850 Datasheet / COA / SDS

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RDC0850

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Mouse GPR20 (NP_775541) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Mouse

Product Datasheets

Product Datasheet

COA

SDS

Background: GPR20

GPR20 is constitutively active in the absence of ligand, leading to continuous activation of its coupled G proteins. When GPR20 was exogenously expressed in HEK293 cells, both the basal level and the prostaglandin E(2)-induced production of cAMP were significantly decreased. Knockdown of GPR20 in PC12h cells resulted in an elevation of the basal cAMP level, suggesting that the endogenous GPR20 achieves a constitutively or spontaneously active conformation. GPR20 may be involved in cellular processes, including control of intracellular cAMP levels and mitogenic signaling.

Long Name

G Protein-coupled Receptor 20

Entrez Gene IDs

2843 (Human); 239530 (Mouse); 60667 (Rat)

Alternate Names

G protein-coupled receptor 20; GPR20; G-protein coupled receptor 20