Mouse IgG2B PE-conjugated Antibody Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
Detection of Mouse IgG Control by Flow Cytometry K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human MICA PE-conjugated Monoclonal Antibody (Catalog # FAB1300P, filled histogram) or Mouse IgG PE-conjugated Isotype Control Antibody (Catalog # IC0041P, open histogram).
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: IgG2B
R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.
Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.
Product Datasheets
Citations for Mouse IgG2B PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5.
Authors: Di X, Zhang G, Zhang Y et al.
Oncotarget
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Evaluating erythropoietin-associated tumor progression using archival tissues from a phase III clinical trial.
Authors: Miller CP, Lowe KA, Valliant-Saunders K, Kaiser JF, Mattern D, Urban N, Henke M, Blau CA
Stem Cells, 2009-09-01;27(9):2353-61.
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Cytokeratin 8/18 protects breast cancer cell lines from TRAIL-induced apoptosis
Authors: Bozza WP, Zhang Y, Zhang B.
Oncotarget
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Enhanced Anti-Melanoma Activity of Nutlin-3a Delivered via Ethosomes: Targeting p53-Mediated Apoptosis in HT144 Cells
Authors: Romani, A;Lodi, G;Casciano, F;Gonelli, A;Secchiero, P;Zauli, G;Bortolini, O;Valacchi, G;Ragno, D;Bondi, A;Benedusi, M;Esposito, E;Voltan, R;
Cells
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Antitumor effects of NK cells expanded by activation pre?processing of autologous feeder cells before irradiation in colorectal cancer
Authors: Koh, EK;Lee, HR;Son, WC;Park, GY;Bae, J;Park, YS;
Oncology letters
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Combinatorial immunotherapy with gemcitabine and ex vivo-expanded NK cells induces anti-tumor effects in pancreatic cancer
Authors: Koh, EK;Lee, HR;Son, WC;Park, GY;Kim, J;Bae, JH;Park, YS;
Scientific reports
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Antineoplastic efficacy profiles of avapritinib and nintedanib in KIT D816V+ systemic mastocytosis: a preclinical study
Authors: L Degenfeld-, S Gamperl, G Stefanzl, AK Schruef, I Sadovnik, K Bauer, D Smiljkovic, G Eisenwort, B Peter, G Greiner, E Hadzijusuf, J Schwaab, WR Sperr, G Hoermann, S Kopanja, Z Szépfalusi, K Hoetzeneck, P Jaksch, A Reiter, M Arock, P Valent
American journal of cancer research, 2023-02-15;13(2):355-378.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Induction of Breast Cancer Cell Apoptosis by TRAIL and Smac Mimetics: Involvement of RIP1 and cFLIP
Authors: Christian Holmgren, Ellen Sunström Thörnberg, Victoria Granqvist, Christer Larsson
Current Issues in Molecular Biology
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Decreased expression of ErbB2 on left ventricular epicardial cells in patients with diabetes mellitus
Authors: JT de Kay, J Carver, B Shevenell, AM Kosta, S Tsibulniko, E Certo, DB Sawyer, S Ryzhov, MP Robich
Cellular Signalling, 2022-05-21;96(0):110360.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Interleukin-6 Signaling in Triple Negative Breast Cancer Cells Elicits the Annexin A1/Formyl Peptide Receptor 1 Axis and Affects the Tumor Microenvironment
Authors: L Vecchi, STS Mota, MAP Zóia, IC Martins, JB de Souza, TG Santos, AO Beserra, VP de Andrade, LR Goulart, TG Araújo
Cells, 2022-05-20;11(10):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
BT7480, a novel fully synthetic Bicycle tumor-targeted immune cell agonist™ (Bicycle TICA™) induces tumor localized CD137 agonism
Authors: Kristen Hurov, Johanna Lahdenranta, Punit Upadhyaya, Eric Haines, Heather Cohen, Elizabeth Repash et al.
Journal for ImmunoTherapy of Cancer
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CD200-CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma
Authors: P Shafiei-Ja, DG Helou, BP Hurrell, E Howard, C Quach, JD Painter, L Galle-Treg, M Li, YE Loh, O Akbari
Nature Communications, 2021-05-05;12(1):2526.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins
Authors: Miguel Ángel Muñoz-Alía, Rebecca A. Nace, Lianwen Zhang, Stephen J. Russell
Cell Reports Medicine
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Mev-stealth: A cd46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum
Authors: MÁ Muñoz-Alía, RA Nace, A Tischer, L Zhang, ES Bah, M Auton, SJ Russell
PloS Pathogens, 2021-02-03;17(2):e1009283.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
CD14+CD16- monocytes are the main precursors of osteoclasts in rheumatoid arthritis via expressing Tyro3TK
Authors: J Xue, L Xu, H Zhu, M Bai, X Li, Z Zhao, H Zhong, G Cheng, X Li, F Hu, Y Su
Arthritis Research & Therapy, 2020-09-21;22(1):221.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
DR3 stimulation of adipose resident ILC2s ameliorates type 2 diabetes mellitus
Authors: P Shafiei-Ja, BP Hurrell, L Galle-Treg, DG Helou, E Howard, J Painter, R Lo, G Lewis, P Soroosh, O Akbari
Nat Commun, 2020-09-18;11(1):4718.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
CD40- and CD95-specific antibody single chain-Baff fusion proteins display BaffR-, TACI- and BCMA-restricted agonism
Authors: Johannes Nelke, Juliane Medler, Daniela Weisenberger, Andreas Beilhack, Harald Wajant
mAbs
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Annexin A1 promotes the nuclear localization of the epidermal growth factor receptor in castration-resistant prostate cancer
Authors: STS Mota, L Vecchi, DA Alves, AO Cordeiro, GS Guimarães, E Campos-Fer, YCP Maia, BC Dornelas, SM Bezerra, VP de Andrade, LR Goulart, TG Araújo
Int. J. Biochem. Cell Biol., 2020-08-25;127(0):105838.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
MicroRNA-222 Regulates Melanoma Plasticity
Authors: MC Lionetti, F Cola, O Chepizhko, MR Fumagalli, F Font-Clos, R Ravasio, S Minucci, P Canzano, M Camera, G Tiana, S Zapperi, CAM Porta
J Clin Med, 2020-08-08;9(8):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
New CXCR4 Antagonist Peptide R (Pep R) Improves Standard Therapy in Colorectal Cancer
Authors: C D'Alterio, A Zannetti, AM Trotta, C Ieranò, M Napolitano, G Rea, A Greco, P Maiolino, S Albanese, G Scognamigl, F Tatangelo, S Tafuto, L Portella, S Santagata, G Nasti, A Ottaiano, R Pacelli, P Delrio, G Botti, S Scala
Cancers (Basel), 2020-07-18;12(7):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Elevated Expression of C-Type Lectin Domain Family 5-Member A (CLEC5A) and Its Relation to Inflammatory Parameters and Disease Course in Adult-Onset Still's Disease
Authors: PK Chen, SL Hsieh, JL Lan, CC Lin, SH Chang, DY Chen
J Immunol Res, 2020-04-23;2020(0):9473497.
Species: Human
Sample Types: Whole Blood
Applications: Flow Cytometry -
Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways
Authors: J Dittmann, T Haydn, P Metzger, GA Ward, M Boerries, M Vogler, S Fulda
Cell Death Differ., 2019-12-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
A novel S1P1 modulator IMMH002 ameliorates psoriasis in multiple animal models
Authors: J Jin, N Xue, Y Liu, R Fu, M Wang, M Ji, F Lai, J Hu, X Wang, Q Xiao, X Zhang, D Yin, L Bai, X Chen, S Rao
Acta Pharm Sin B, 2019-11-14;10(2):276-288.
Species: Hamster
Sample Types: Whole Cells
Applications: Flow Cytometry -
Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis
Authors: Rosario Luque-Martin, Jan Van den Bossche, Rebecca C. Furze, Annette E. Neele, Saskia van der Velden, Marion J.J. Gijbels et al.
Frontiers in Pharmacology
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Effect of monocyte seeding density on dendritic cell generation in an automated perfusion-based culture system
Authors: Andrew Kozbial, Lekhana Bhandary, Shashi K. Murthy
Biochemical Engineering Journal
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TIM-1 As a Signal Receptor Triggers Dengue Virus-Induced Autophagy
Authors: LW Chu, CJ Yang, KJ Peng, PL Chen, SJ Wang, YH Ping
Int J Mol Sci, 2019-10-02;20(19):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Influence of endocrine therapy on the ratio of androgen receptor (AR) to estrogen receptor (ER) positive circulating epithelial tumor cells (CETCs) in breast cancer
Authors: M Pizon, D Lux, U Pachmann, K Pachmann, D Schott
J Transl Med, 2018-12-14;16(1):356.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Simultaneous targeting of EGFR, HER2 and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines
Authors: I De Pauw, F Lardon, J Van den Bo, H Baysal, E Fransen, V Deschoolme, P Pauwels, M Peeters, JB Vermorken, A Wouters
Mol Oncol, 2018-05-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Apoptosis-sensitizing activity of birinapant in head and neck squamous cell carcinoma cell lines
Authors: RC Brands, MJJ Scheurer, S Hartmann, A Seher, AC Kübler, UDA Müller-Ric
Oncol Lett, 2018-01-12;15(3):4010-4016.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of hiPSTZ16 (ISMMSi003-A) cell line from normal human foreskin fibroblasts
Authors: M Dejosez, TP Zwaka
Stem Cell Res, 2017-12-02;26(0):44-46.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages
Authors: OJ Lara-Guzmá, Á Gil-Izquie, S Medina, E Osorio, R Álvarez-Qu, N Zuluaga, C Oger, JM Galano, T Durand, K Muñoz-Dura
Redox Biol, 2017-11-22;15(0):1-11.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Resveratrol promotes MICA/B expression and natural killer cell lysis of breast cancer cells by suppressing c-Myc/miR-17 pathway
Authors: Jie Pan, Jiaying Shen, Wengong Si, Chengyong Du, Danni Chen, Liang Xu et al.
Oncotarget
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IL-7 Restores T Lymphocyte Immunometabolic Failure in Septic Shock Patients through mTOR Activation
Authors: F Venet, J Demaret, BJ Blaise, C Rouget, T Girardot, E Idealisoa, T Rimmelé, F Mallet, A Lepape, J Textoris, G Monneret
J. Immunol., 2017-07-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Isoform localization of Dectin-1 regulates the signaling quality of anti-fungal immunity
Authors: M Fischer, JP Müller, B Spies-Weis, C Gräfe, O Kurzai, K Hünniger, A Hochhaus, S Scholl, U Schnetzke
Eur. J. Immunol, 2017-04-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Systemic frequencies of T helper 1 and T helper 17 cells in patients with age-related macular degeneration: A case-control study
Authors: Amardeep Singh, Yousif Subhi, Marie Krogh Nielsen, Mads Krüger Falk, Sara Maj Hyldig Matzen, Finn Sellebjerg et al.
Scientific Reports
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The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion
Authors: A Koenen, A Babendreye, J Schumacher, T Pasqualon, N Schwarz, A Seifert, X Deupi, A Ludwig, D Dreymuelle
PLoS ONE, 2017-03-07;12(3):e0173486.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
Authors: Lars Fugger
Sci Transl Med, 2016-11-02;8(363):363ra149.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors
Authors: Sunao Sugita, Yuko Iwasaki, Kenichi Makabe, Takafumi Kimura, Takaomi Futagami, Shinji Suegami et al.
Stem Cell Reports
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Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia
Authors: Mike Fischer, Baerbel Spies-Weisshart, Karin Schrenk, Bernd Gruhn, Susan Wittig, Anita Glaser et al.
PLOS ONE
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Expression of arginase I and inducible nitric oxide synthase in the peripheral blood and lymph nodes of HIV-positive patients
Authors: NAICHUN ZHANG, JIANNING DENG, FENGYAO WU, XIANGCHAN LU, LEI HUANG, MIN ZHAO
Molecular Medicine Reports
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Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses
Authors: Wei-Bei Wang, Men-Luh Yen, Ko-Jiunn Liu, Pei-Ju Hsu, Ming-Hong Lin, Pei-Min Chen et al.
Stem Cell Reports
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CXCR6 expression in non-small cell lung carcinoma supports metastatic process via modulating metalloproteinases
Authors: Hina Mir, Rajesh Singh, Goetz H. Kloecker, James W. Lillard, Shailesh Singh
Oncotarget
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Aberrant CCR4 expression is involved in tumor invasion of lymph node-negative human gastric cancer.
Authors: Yang, Yongmei, Du, Lutao, Yang, Xiaoyun, Qu, Ailin, Zhang, Xin, Zhou, Chengjun, Wang, Chuanxin
PLoS ONE, 2015-03-19;10(3):e0120059.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The role of selected flavonols in tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) expression on activated RAW 264.7 macrophages.
Authors: Warat M, Sadowski T, Szliszka E, Krol W, Czuba Z
Molecules, 2015-01-08;20(1):900-12.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells.
Authors: Huang L, Nakayama H, Klagsbrun M, Mulliken J, Bischoff J
Stem Cells, 2015-01-01;33(1):133-45.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Chrysin, apigenin and acacetin inhibit tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) on activated RAW264.7 macrophages.
Authors: Warat M, Szliszka E, Korzonek-Szlacheta I, Krol W, Czuba Z
Int J Mol Sci, 2014-06-27;15(7):11510-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
CXCL16 and CXCR6 are coexpressed in human lung cancer in vivo and mediate the invasion of lung cancer cell lines in vitro.
Authors: Hu, Weidong, Liu, Yue, Zhou, Wenhui, Si, Lianlian, Ren, Liang
PLoS ONE, 2014-06-04;9(6):e99056.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cells.
Authors: Robinet P, Baychelier F, Fontaine T, Picard C, Debre P, Vieillard V, Latge J, Elbim C
J Immunol, 2014-04-30;192(11):5332-42.
Species: Human
Sample Types: Whole Blood
Applications: Flow Cytometry -
Endothelial cell-derived chemerin promotes dendritic cell transmigration.
Authors: Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S
J Immunol, 2014-01-27;192(5):2366-73.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control -
IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer.
Authors: Kachroo P, Lee M, Zhang L, Baratelli F, Lee G, Srivastava M, Wang G, Walser T, Krysan K, Sharma S, Dubinett S, Lee J
J Exp Clin Cancer Res, 2013-11-25;32(0):97.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control -
MBL-mediated opsonophagocytosis of Candida albicans by human neutrophils is coupled with intracellular Dectin-1-triggered ROS production.
Authors: Li D, Dong B, Tong Z, Wang Q, Liu W, Wang Y, Liu W, Chen J, Xu L, Chen L, Duan Y
PLoS ONE, 2012-12-11;7(12):e50589.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Decreased pre-surgical CD34+/CD144+ cell number in patients undergoing coronary artery bypass grafting compared to coronary artery disease-free valvular patients
Authors: Santiago Redondo, Álvaro González-Rocafort, Jorge Navarro-Dorado, Marta Ramajo, Mihail Hristov, Antonio Gordillo-Moscoso et al.
Journal of Cardiothoracic Surgery
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WEE1 Inhibition Sensitizes Basal Breast Cancer Cells to TRAIL-Induced Apoptosis
Authors: Sireesha V. Garimella, Andrea Rocca, Stanley Lipkowitz
Molecular Cancer Research
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Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.
Authors: Noyce RS, Bondre DG, Ha MN
PLoS Pathog., 2011-08-25;7(8):e1002240.
Species: Hamster, Human
Sample Types: Whole Cells
Applications: Control -
TNFR1 and TNFR2 regulate the extrinsic apoptotic pathway in myeloma cells by multiple mechanisms
Authors: H Rauert, T Stühmer, R Bargou, H Wajant, D Siegmund
Cell Death & Disease
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The dietary flavonol fisetin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells.
Authors: Szliszka E, Helewski KJ, Mizgala E, Krol W
Int. J. Oncol., 2011-07-06;39(4):771-9.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Cisplatin sensitizes human hepatocellular carcinoma cells, but not hepatocytes and mesenchymal stem cells, to TRAIL within a therapeutic window partially depending on the upregulation of DR5
Authors: Bo Zhang, Hong Shan, Dan Li, Zheng-Ran Li, Kang-Shun Zhu, Zai-Bo Jiang et al.
Oncology Reports
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Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis.
Authors: McDermott DH, De Ravin SS, Jun HS
Blood, 2010-07-08;116(15):2793-802.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Epigenetic silencing of death receptor 4 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in gliomas.
Authors: Elias A, Siegelin MD, Steinmuller A, von Deimling A, Lass U, Korn B, Mueller W
Clin. Cancer Res., 2009-08-25;15(17):5457-65.
Species: Human
Sample Types: Whole Cells
Applications: Control, Flow Cytometry -
Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection.
Authors: Ehlin-Henriksson B, Liang W, Cagigi A, Mowafi F, Klein G, Nilsson A
Immunology, 2009-08-01;127(4):549-57.
Species: Human
Sample Types: Whole Cells
Applications: Control -
The impact of proliferative potential of umbilical cord-derived endothelial progenitor cells and hypoxia on vascular tubule formation in vitro.
Authors: Zhang Y, Fisher N, Newey SE
Stem Cells Dev., 2009-03-01;18(2):359-75.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
Authors: Ahern D, Lloyd CM, Robinson DS
Allergy, 2009-02-07;64(8):1121-9.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.
Authors: Dai CL, Tiwari AK, Wu CP, Su XD, Wang SR, Liu DG, Ashby CR, Huang Y, Robey RW, Liang YJ, Chen LM, Shi CJ, Ambudkar SV, Chen ZS, Fu LW
Cancer Res., 2008-10-01;68(19):7905-14.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes
Authors: L Galle-Treg, I Sankaranar, BP Hurrell, E Howard, R Lo, H Maazi, G Lewis, H Banie, AL Epstein, P Hu, VK Rehan, FD Gilliland, H Allayee, P Soroosh, AH Sharpe, O Akbari
Nat Commun, 2019-02-12;10(1):713.
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Tubulin couples death receptor 5 to regulate apoptosis.
Authors: Twomey JD, Zhao L, Luo S et al.
Oncotarget
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