Mouse IL-13 Culture Media Quantikine ELISA Summary
Product Summary
Recovery
The recovery of mouse IL-13 spiked to levels throughout the range of the assay was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Supernates (n=13) | 99 | 89-119 |
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: IL-13
IL-13 (Interleukin-13) plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. It promotes B cell activation, immunoglobulin class switching to IgE, and the upregulation of CD23/Fc epsilon RII. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 R alpha 2 binds IL-13 and prevents IL-13 from signaling through the IL-13 R alpha 1/IL-4 R alpha complex. IL-13-bound IL-13 R alpha 2 can directly promote tumor cell invasiveness and the development of tissue fibrosis.
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 50 µL of Assay Diluent to each well.
- Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
- Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.
- Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
- Aspirate and wash 5 times.
- Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
- Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Mouse IL-13 Culture Media Quantikine ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
136
Citations: Showing 1 - 10
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Enoximone alleviates atopic dermatitis-like skin inflammation via inhibition of type 2 T helper cell development
Authors: Song, JY;Lee, YJ;Lee, SH;Lee, JY;
International immunopharmacology
Species: Mouse
Sample Types: Serum
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Helminth alleviates COVID-19-related cytokine storm in an IL-9-dependent way
Authors: Cao, Z;Wang, J;Liu, X;Liu, Y;Li, F;Liu, M;Chiu, S;Jin, X;
mBio
Species: Mouse
Sample Types: Serum
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Tumor Growth Ameliorates Cardiac Dysfunction and Suppresses Fibrosis in a Mouse Model for Duchenne Muscular Dystrophy
Authors: Achlaug, L;Awwad, L;Langier Goncalves, I;Goldenberg, T;Aronheim, A;
International journal of molecular sciences
Species: Mouse
Sample Types: Serum
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Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s
Authors: Irie, M;Kabata, H;Sasahara, K;Kurihara, M;Shirasaki, Y;Kamatani, T;Baba, R;Matsusaka, M;Koga, S;Masaki, K;Miyata, J;Araki, Y;Kikawada, T;Kabe, Y;Suematsu, M;Yamagishi, M;Uemura, S;Moro, K;Fukunaga, K;
Cell reports
Species: Mouse, Transgenic Mouse
Sample Types: Cell Culture Supernates, BALF
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Dasatinib attenuates airway inflammation of asthma exacerbation in mice induced by house dust mites and dsRNA
Authors: Y Nishimoto, D Ando, K Irie, I Kainuma, Y Katayama, S Sato, T Suzuki, M Harada, T Yoshida, K Ito, Y Kizawa
Biochemistry and Biophysics Reports, 2022-12-02;33(0):101402.
Species: Mouse
Sample Types: BALF
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Cinnamomum cassia (L.) J.Presl Alleviates Allergic Responses in Asthmatic Mice via Suppression of MAPKs and MMP-9
Authors: JO Lim, YH Kim, IS Lee, WI Kim, SJ Lee, SW Pak, IS Shin, T Kim
Frontiers in Pharmacology, 2022-08-11;13(0):906916.
Species: Mouse
Sample Types: Cell Culture Supernates
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Psychological Stress Exacerbates Inflammation of the Ileum via the Corticotropin-Releasing Hormone-Mast Cell Axis in a Mouse Model of Eosinophilic Enteritis
Authors: A Kanamori, F Tanaka, M Ominami, Y Nadatani, S Fukunaga, K Otani, S Hosomi, N Kamata, Y Nagami, K Taira, Y Fujiwara
International Journal of Molecular Sciences, 2022-08-01;23(15):.
Species: Mouse
Sample Types: Tissue Homogenates
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Cluster of Differentiation 147 (CD147) serves as a promoter of atherosclerosis in patients with cerebral infarction
Authors: GJ Wang, X Dong, Y Li
European review for medical and pharmacological sciences, 2022-08-01;26(16):5710-5717.
Species: Human
Sample Types: Serum
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Experimental Schistosoma japonicum-induced pulmonary hypertension
Authors: B Kassa, MH Lee, R Kumar, C Mickael, L Sanders, RM Tuder, M Mentink-Ka, BB Graham
PloS Neglected Tropical Diseases, 2022-04-13;16(4):e0010343.
Species: Mouse
Sample Types: Tissue Homogenates
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Chronic Allergen Challenge Induces Corticosteroid Insensitivity With Persistent Airway Remodeling and Type 2 Inflammation
Authors: BW Lewis, ML Ford, AQ Khan, J Walum, RD Britt
Frontiers in Pharmacology, 2022-04-11;13(0):855247.
Species: Mouse
Sample Types: BALF
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Immunoregulatory effects of Lactococcus lactis-derived extracellular vesicles in allergic asthma
Authors: DH Lee, HK Park, HR Lee, H Sohn, S Sim, HJ Park, YS Shin, YK Kim, Y Choi, HS Park
Clinical and translational allergy, 2022-03-01;12(3):e12138.
Species: Mouse
Sample Types: BALF
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Nematode ascarosides attenuate mammalian type 2 inflammatory responses
Authors: K Shinoda, A Choe, K Hirahara, M Kiuchi, K Kokubo, T Ichikawa, JS Hoki, AS Suzuki, N Bose, JA Appleton, RV Aroian, FC Schroeder, PW Sternberg, T Nakayama
Proceedings of the National Academy of Sciences of the United States of America, 2022-03-01;119(9):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Acteoside exerts immunomodulatory effects on dendritic cells via aryl hydrocarbon receptor activation and ameliorates Th2-mediated allergic asthma by inducing Foxp3+ regulatory T cells
Authors: JH Chang, HC Chuang, G Hsiao, TY Hou, CC Wang, SC Huang, BY Li, YL Lee
International immunopharmacology, 2022-02-03;106(0):108603.
Species: Mouse
Sample Types: Cell Culture Supernates
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Glutaminolysis is required in maintaining immune regulatory functions in B cells
Authors: JQ Liu, XR Geng, TY Hu, LH Mo, XQ Luo, SY Qiu, DB Liu, ZG Liu, JB Shao, ZQ Liu, PC Yang
Mucosal Immunology, 2022-01-10;0(0):.
Species: Mouse
Sample Types: Nasal Secretion
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Eosinophil extracellular traps drive asthma progression through neuro-immune signals
Authors: Y Lu, Y Huang, J Li, J Huang, L Zhang, J Feng, J Li, Q Xia, Q Zhao, L Huang, S Jiang, S Su
Nature Cell Biology, 2021-10-06;23(10):1060-1072.
Species: Mouse
Sample Types: BALF
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Mechanism of chlorogenic acid in alveolar macrophage polarization in Klebsiella pneumoniae-induced pneumonia
Authors: QR Li, SR Tan, L Yang, W He, L Chen, FX Shen, Z Wang, HF Wang
Journal of leukocyte biology, 2021-09-29;0(0):.
Species: Mouse
Sample Types: BALF
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Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes
Authors: S Lee, A Ishitsuka, T Kuroki, YH Lin, A Shibuya, T Hongu, Y Funakoshi, Y Kanaho, K Nagata, A Kawaguchi
JCI Insight, 2021-08-23;6(16):.
Species: Mouse
Sample Types: Cell Culture Supernates
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HDAC4 induces the development of asthma by increasing Slug-upregulated CXCL12 expression through KLF5 deacetylation
Authors: W Wei, W Chen, N He
Journal of Translational Medicine, 2021-06-12;19(1):258.
Species: Mouse
Sample Types: Cell Culture Supernates
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Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease
Authors: Á Rol, T Todorovski, P Martin-Mal, A Escolà, E Gonzalez-R, E Aragón, X Verdaguer, M Vallès-Mir, J Farrera-Si, E Puig, J Fernández-, B Ponsati, M Delgado, A Riera, MJ Macias
Nature Communications, 2021-03-25;12(1):1869.
Species: Mouse
Sample Types: Cell Culture Supernates
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Alleviation of Ulcerative Colitis Potentially through th1/th2 Cytokine Balance by a Mixture of Rg3-enriched Korean Red Ginseng Extract and Persicaria tinctoria
Authors: E Saba, YY Lee, MH Rhee, SD Kim
Molecules, 2020-11-10;25(22):.
Species: Mouse
Sample Types: Plasma
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COX Inhibition Increases Alternaria-Induced Pulmonary Group 2 Innate Lymphoid Cell Responses and IL-33 Release in Mice
Authors: W Zhou, J Zhang, S Toki, K Goleniewsk, AE Norlander, DC Newcomb, P Wu, KL Boyd, H Kita, RS Peebles
J. Immunol., 2020-07-20;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Maternal Obesity in Mice Exacerbates the Allergic Inflammatory Response in the Airways of Male Offspring
Authors: RR E-Lacerda, CJ Teixeira, S Bordin, E Antunes, GF Anhê
Nutrients, 2019-12-01;11(12):.
Species: Mouse
Sample Types: BALF
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Der p2?A20 DNA vaccine attenuates allergic inflammation in mice with allergic rhinitis
Authors: W Hu, L Ma, G Yang, X Zeng, J Liu, B Cheng, T Hu, H Zhao, Z Liu
Mol Med Rep, 2019-10-21;0(0):.
Species: Mouse
Sample Types: Serum
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Innate Lymphoid Cells in the Induction of Obesity
Authors: T Sasaki, K Moro, T Kubota, N Kubota, T Kato, H Ohno, S Nakae, H Saito, S Koyasu
Cell Rep, 2019-07-02;28(1):202-217.e7.
Species: Mouse
Sample Types: Cell Culture Supernates
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Effect of Lactobacillus rhamnosus GG immunopathologic changes in chronic mouse asthma model
Authors: CT Wu, FH Lin, YT Lee, MS Ku, KH Lue
J Microbiol Immunol Infect, 2019-03-23;0(0):.
Species: Mouse
Sample Types: BALF
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Andrographolide prevented toluene diisocyanate-induced occupational asthma and aberrant airway E-cadherin distribution via p38 MAPK-dependent Nrf2 induction
Authors: I Sulaiman, K Tan, N Mohtarrudi, JC Woei Lim, J Stanslas
Pulm Pharmacol Ther, 2018-09-21;0(0):.
Species: Mouse
Sample Types: BALF
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Multi-Walled Carbon Nanotubes Augment Allergic Airway Eosinophilic Inflammation by Promoting Cysteinyl Leukotriene Production
Authors: S Carvalho, M Ferrini, L Herritt, A Holian, Z Jaffar, K Roberts
Front Pharmacol, 2018-06-05;9(0):585.
Species: Mouse
Sample Types: BALF
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Effects of the Th2-dominant milieu on allergic responses in Der f 1-activated mouse basophils and mast cells
Authors: MH Yi, HP Kim, KY Jeong, JY Kim, IY Lee, TS Yong
Sci Rep, 2018-05-16;8(1):7706.
Species: Mouse
Sample Types: Cell Culture Supernates
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TIM?4 blockade of KCs combined with exogenous TGF?β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts
Authors: H Wu, X Xu, J Li, J Gong, M Li
Int. J. Mol. Med., 2018-03-30;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Glucagon-like peptide-2 improves intestinal immune function and diminishes bacterial translocation in a mouse model of parenteral nutrition
Authors: Q Lei, J Bi, H Chen, F Tian, X Gao, N Li, X Wang
Nutr Res, 2017-10-10;49(0):56-66.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: ELISA Capture -
Fungal immunomodulatory protein-fve could modulate airway remodel through by affect IL17 cytokine
Authors: YT Lee, CT Wu, HL Sun, JL Ko, KH Lue
J Microbiol Immunol Infect, 2017-06-29;0(0):.
Species: Mouse
Sample Types: BALF
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STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection
Authors: MT Stier, K Goleniewsk, JY Cephus, DC Newcomb, TP Sherrill, KL Boyd, MH Bloodworth, ML Moore, K Chen, JK Kolls, RS Peebles
J. Immunol., 2017-06-02;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Effect of a retinoid X receptor partial agonist on airway inflammation and hyperresponsiveness in a murine model of asthma
Authors: U Fujii, N Miyahara, A Taniguchi, N Oda, D Morichika, E Murakami, H Nakayama, K Waseda, M Kataoka, H Kakuta, M Tanimoto, A Kanehiro
Respir. Res, 2017-01-23;18(1):23.
Species: Mouse
Sample Types: BALF
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Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma
EBioMedicine, 2016-12-21;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis
Sci Rep, 2016-12-14;6(0):39075.
Species: Mouse
Sample Types: Tissue Homogenates
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PGI2 Controls Pulmonary NK Cells That Prevent Airway Sensitization to House Dust Mite Allergen
Authors: Bryan Simons
J. Immunol, 2016-11-28;0(0):.
Species: Mouse
Sample Types: BALF
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Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease
Authors: S Löser, LG Gregory, Y Zhang, K Schaefer, SA Walker, J Buckley, L Denney, CH Dean, WOC Cookson, MF Moffatt, CM Lloyd
J. Allergy Clin. Immunol., 2016-09-10;139(5):1496-1507.e3.
Species: Mouse
Sample Types: Tissue Homogenates
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Increased mitochondrial arginine metabolism supports bioenergetics in asthma
J Clin Invest, 2016-05-23;0(0):.
Species: Mouse
Sample Types: BALF
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PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 Transcription in Dendritic Cells.
Authors: Yashiro T, Kubo M, Ogawa H, Okumura K, Nishiyama C
PLoS ONE, 2015-09-11;10(9):e0137699.
Species: Mouse
Sample Types: Cell Culture Supernates
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G-protein-coupled estrogen receptor agonist suppresses airway inflammation in a mouse model of asthma through IL-10.
Authors: Itoga M, Konno Y, Moritoki Y, Saito Y, Ito W, Tamaki M, Kobayashi Y, Kayaba H, Kikuchi Y, Chihara J, Takeda M, Ueki S, Hirokawa M
PLoS ONE, 2015-03-31;10(3):e0123210.
Species: Mouse
Sample Types: BALF
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Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.
Authors: Mishra, Amarjit, Brown, Alexandr, Yao, Xianglan, Yang, Shutong, Park, Sung-Jun, Liu, Chengyu, Dagur, Pradeep, McCoy, J Philip, Keeran, Karen J, Nugent, Gayle Z, Jeffries, Kenneth, Qu, Xuan, Yu, Zu-Xi, Levine, Stewart, Chung, Jay H
Nat Commun, 2015-02-18;6(0):6224.
Species: Mouse
Sample Types: Cell Culture Supernates
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Impact of ozone exposure on the response to glucocorticoid in a mouse model of asthma: involvements of p38 MAPK and MKP-1.
Authors: Bao, Aihua, Li, Feng, Zhang, Min, Chen, Yuqing, Zhang, Pengyu, Zhou, Xin
Respir Res, 2014-10-08;15(0):126.
Species: Mouse
Sample Types: BALF
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STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.
Authors: Dulek D, Newcomb D, Toki S, Goliniewska K, Cephus J, Reiss S, Bates J, Crowe J, Boyd K, Moore M, Zhou W, Peebles R
J Virol, 2014-06-11;88(17):9655-72.
Species: Mouse
Sample Types: Tissue Homogenates
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Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory mucosa.
Authors: Hara K, Iijima K, Elias M, Seno S, Tojima I, Kobayashi T, Kephart G, Kurabayashi M, Kita H
J Immunol, 2014-03-24;192(9):4032-42.
Species: Mouse
Sample Types: BALF
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Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
J Immunol, 2014-03-21;192(8):3569-81.
Species: Mouse
Sample Types: Tissue Homogenates
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Leishmania donovani targets tumor necrosis factor receptor-associated factor (TRAF) 3 for impairing TLR4-mediated host response.
Authors: Gupta P, Giri J, Srivastav S, Chande A, Mukhopadhyaya R, Das P, Ukil A
FASEB J, 2014-01-03;28(4):1756-68.
Species: Mouse
Sample Types: Cell Culture Supernates
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Antibody to mCLCA3 suppresses symptoms in a mouse model of asthma.
Authors: Song L, Liu D, Wu C, Wu S, Yang J, Ren F, Li Y
PLoS ONE, 2013-12-09;8(12):e82367.
Species: Mouse
Sample Types: BALF
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Interleukin-33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells.
Authors: Jovanovic I, Pejnovic N, Radosavljevic G, Pantic J, Milovanovic M, Arsenijevic N, Lukic M
Int J Cancer, 2013-10-10;134(7):1669-82.
Species: Mouse
Sample Types: Serum
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Genetic vaccine for respiratory syncytial virus provides protection without disease potentiation.
Authors: Johnson T, Rangel D, Graham B, Brough D, Gall J
Mol Ther, 2013-06-10;22(1):196-205.
Species: Mouse
Sample Types: Cell Culture Supernates
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Induction of the specific allergic immune response is independent of proteases from the fungus Alternaria alternata.
Authors: Denis O, Vincent M, Havaux X, De Prins S, Treutens G, Huygen K
Eur J Immunol, 2013-02-20;43(4):907-17.
Species: Mouse
Sample Types: Cell Culture Supernates
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TLR-mediated distinct IFN-gamma/IL-10 pattern induces protective immunity against murine visceral leishmaniasis.
Eur. J. Immunol., 2012-08-01;42(8):2087-99.
Species: Mouse
Sample Types: Cell Culture Supernates
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Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor.
J. Exp. Med., 2012-07-23;209(8):1493-503.
Species: Mouse
Sample Types: Cell Culture Supernates
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IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs.
Authors: Bartemes KR, Iijima K, Kobayashi T, Kephart GM, McKenzie AN, Kita H
J. Immunol., 2011-12-23;188(3):1503-13.
Species: Mouse
Sample Types: BALF
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Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent.
Authors: Provoost S, Maes T, Joos GF, Tournoy KG
J. Allergy Clin. Immunol., 2011-09-08;129(2):483-91.
Species: Mouse
Sample Types: BALF
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IL-22 Is Produced by Innate Lymphoid Cells and Limits Inflammation in Allergic Airway Disease.
Authors: Taube C, Tertilt C, Gyulveszi G, Dehzad N, Kreymborg K, Schneeweiss K, Michel E, Reuter S, Renauld JC, Arnold-Schild D, Schild H, Buhl R, Becher B
PLoS ONE, 2011-07-18;6(7):e21799.
Species: Mouse
Sample Types: BALF
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Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity.
Authors: Barlow JL, Flynn RJ, Ballantyne SJ, McKenzie AN
Clin. Exp. Allergy, 2011-07-04;41(10):1447-55.
Species: Mouse
Sample Types: BALF
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IL-33-activated dendritic cells are critical for allergic airway inflammation.
Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
Eur. J. Immunol., 2011-05-25;41(6):1675-86.
Species: Mouse
Sample Types: BALF
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Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
Am. J. Pathol., 2011-05-10;179(1):302-14.
Species: Mouse
Sample Types: Tissue Homogenates
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Interleukin-13 promotes susceptibility to chlamydial infection of the respiratory and genital tracts.
Authors: Asquith KL, Horvat JC, Kaiko GE
PLoS Pathog., 2011-05-05;7(5):e1001339.
Species: Mouse
Sample Types: Cell Culture Supernates
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The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling.
Authors: Doherty TA, Soroosh P, Khorram N, Fukuyama S, Rosenthal P, Cho JY, Norris PS, Choi H, Scheu S, Pfeffer K, Zuraw BL, Ware CF, Broide DH, Croft M
Nat. Med., 2011-04-17;17(5):596-603.
Species: Mouse
Sample Types: Tissue Homogenates
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Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma.
Authors: Hirata H, Arima M, Fukushima Y, Honda K, Sugiyama K, Tokuhisa T, Fukuda T
Clin. Exp. Allergy, 2011-03-24;41(8):1133-42.
Species: Mouse
Sample Types: BALF
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Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation.
Authors: Louten J, Rankin AL, Li Y
Int. Immunol., 2011-03-21;23(5):307-15.
Species: Mouse
Sample Types: BALF
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The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.
Authors: Vultaggio A, Nencini F, Pratesi S, Maggi L, Guarna A, Annunziato F, Romagnani S, Parronchi P, Maggi E
J. Immunol., 2011-03-09;186(8):4707-15.
Species: Mouse
Sample Types: Serum
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Control of mouse graft-versus-host disease following allogeneic bone marrow transplantation by blocking the CD28/B7 signaling pathway with lentiviral vector-mediated RNA interference.
Authors: Sang W, Zhou C, Cheng N, Li Z, Zeng L, Xu K
Immunol. Lett., 2011-01-26;136(2):194-202.
Species: Mouse
Sample Types: Plasma
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Anti-Asthma Simplified Herbal Medicine Intervention-induced long-lasting tolerance to allergen exposure in an asthma model is interferon-gamma, but not transforming growth factor-beta dependent.
Authors: Srivastava K, Zhang T, Yang N, Sampson H, Li XM
Clin. Exp. Allergy, 2010-11-01;40(11):1678-88.
Species: Mouse
Sample Types: BALF
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Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation.
Authors: Wright PL, Yu J, Di YP
J. Exp. Med., 2010-10-25;207(12):2595-607.
Species: Mouse
Sample Types: BALF
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Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling.
Authors: Graham BB, Mentink-Kane MM, El-Haddad H
Am. J. Pathol., 2010-07-29;177(3):1549-61.
Species: Mouse
Sample Types: Tissue Homogenates
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Mucosal vaccination using claudin-4-targeting.
Authors: Kakutani H, Kondoh M, Fukasaka M, Suzuki H, Hamakubo T, Yagi K
Biomaterials, 2010-07-01;31(20):5463-71.
Species: Mouse
Sample Types: Serum
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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity.
Authors: Neill DR, Wong SH, Bellosi A, Flynn RJ, Daly M, Langford TK, Bucks C, Kane CM, Fallon PG, Pannell R, Jolin HE, McKenzie AN
Nature, 2010-03-03;464(7293):1367-70.
Species: Mouse
Sample Types: Cell Culture Supernates
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Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2009-12-29;49(3):256-63.
Species: Mouse
Sample Types: BALF
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House dust mite induces direct airway inflammation in vivo: implications for future disease therapy?
Authors: De Alba J, Raemdonck K, Dekkak A, Collins M, Wong S, Nials AT, Knowles RG, Belvisi MG, Birrell MA
Eur. Respir. J., 2009-10-19;35(6):1377-87.
Species: Mouse
Sample Types: BALF
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Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13.
Authors: He R, Kim HY, Yoon J, Oyoshi MK, MacGinnitie A, Goya S, Freyschmidt EJ, Bryce P, McKenzie AN, Umetsu DT, Oettgen HC, Geha RS
J. Allergy Clin. Immunol., 2009-10-01;124(4):761-70.e1.
Species: Mouse
Sample Types: Cell Culture Supernates
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Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice.
Authors: Mizutani N, Nabe T, Yoshino S
J. Immunol., 2009-08-14;183(6):4039-46.
Species: Mouse
Sample Types: BALF
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A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice.
Authors: Page K, Ledford JR, Zhou P, Wills-Karp M
J. Immunol., 2009-08-10;183(5):3400-8.
Species: Mouse
Sample Types: Tissue Homogenates
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Peroxisome proliferator-activated receptor gamma agonist down-regulates IL-17 expression in a murine model of allergic airway inflammation.
Authors: Park SJ, Lee KS, Kim SR, Min KH, Choe YH, Moon H, Chae HJ, Yoo WH, Lee YC
J. Immunol., 2009-07-29;183(5):3259-67.
Species: Mouse
Sample Types: BALF
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Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner.
Authors: Kottyan LC, Collier AR, Cao KH, Niese KA, Hedgebeth M, Radu CG, Witte ON, Khurana Hershey GK, Rothenberg ME, Zimmermann N
Blood, 2009-07-29;114(13):2774-82.
Species: Mouse
Sample Types: Cell Lysates
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Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production.
Authors: Gueders MM, Paulissen G, Crahay C, Quesada-Calvo F, Hacha J, Van Hove C, Tournoy K, Louis R, Foidart JM, Noel A, Cataldo DD
Inflamm. Res., 2009-06-09;58(12):845-54.
Species: Mouse
Sample Types: BALF
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Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+CD25+Foxp3+ T cell recruitment.
Authors: Park SK, Cho MK, Park HK, Lee KH, Lee SJ, Choi SH, Ock MS, Jeong HJ, Lee MH, Yu HS
J. Immunol., 2009-06-01;182(11):6907-14.
Species: Mouse
Sample Types: BALF
-
Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis.
Authors: Izumo T, Kondo M, Nagai A
Eur. Respir. J., 2009-05-21;34(6):1444-51.
Species: Mouse
Sample Types: BALF
-
Intranasal challenge with increasing ovalbumin doses differently affects airway hyperresponsiveness and inflammatory cell accumulation in mouse model of asthma.
Authors: Bosnjak B, Ivetic Tkalcevic V, Duric K, Belamaric D, Cuzic S, Ferencic Z, Brajsa K, Glojnaric I, Antolovic R, Hrvacic B
Inflamm. Res., 2009-05-08;58(11):773-81.
Species: Mouse
Sample Types: BALF
-
Lovastatin inhibits antigen-induced airway eosinophilia without affecting the production of inflammatory mediators in mice.
Authors: Chiba Y, Sato S, Misawa M
Inflamm. Res., 2009-05-06;0(0):.
Species: Mouse
Sample Types: BALF
-
Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model.
Authors: Kim DY, Park JW, Jeoung D, Ro JY
Eur. J. Pharmacol., 2009-04-05;612(1):98-105.
Species: Mouse
Sample Types: BALF
-
TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity.
Authors: Johnson TR, Rao S, Seder RA, Chen M, Graham BS
Vaccine, 2009-04-03;27(23):3045-52.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice.
Authors: Shinagawa K, Ploplis VA, Castellino FJ
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-03-13;296(5):L763-70.
Species: Mouse
Sample Types: BALF
-
Temporal changes in myeloid cells in the cervix during pregnancy and parturition.
Authors: Timmons BC, Fairhurst AM, Mahendroo MS
J. Immunol., 2009-03-01;182(5):2700-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Osteopontin deficiency protects against airway remodeling and hyperresponsiveness in chronic asthma.
Authors: Simoes DC, Xanthou G, Petrochilou K, Panoutsakopoulou V, Roussos C, Gratziou C
Am. J. Respir. Crit. Care Med., 2009-02-20;179(10):894-902.
Species: Mouse
Sample Types: Tissue Homogenates
-
The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation.
Authors: Claudio E, Sonder SU, Saret S, Carvalho G, Ramalingam TR, Wynn TA, Chariot A, Garcia-Perganeda A, Leonardi A, Paun A, Chen A, Ren NY, Wang H, Siebenlist U
J. Immunol., 2009-02-01;182(3):1617-30.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7.
Authors: Vultaggio A, Nencini F, Fitch PM, Fili L, Maggi L, Fanti P, deVries A, Beccastrini E, Palandri F, Manuelli C, Bani D, Giudizi MG, Guarna A, Annunziato F, Romagnani S, Maggi E, Howie SE, Parronchi P
J. Immunol., 2009-01-15;182(2):880-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Coexpression of TGF-beta1 and IL-10 enables regulatory T cells to completely suppress airway hyperreactivity.
Authors: Presser K, Schwinge D, Wegmann M, Huber S, Schmitt S, Quaas A, Maxeiner JH, Finotto S, Lohse AW, Blessing M, Schramm C
J. Immunol., 2008-12-01;181(11):7751-8.
Species: Mouse
Sample Types: BALF
-
Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses.
Authors: Zhou W, Newcomb DC, Moore ML, Goleniewska K, O'Neal JF, Peebles RS
J. Immunol., 2008-10-15;181(8):5360-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.
Authors: Pesu M, Watford WT, Wei L, Xu L, Fuss I, Strober W, Andersson J, Shevach EM, Quezado M, Bouladoux N, Roebroek A, Belkaid Y, Creemers J, O'Shea JJ
Nature, 2008-09-11;455(7210):246-50.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma.
Authors: Ryman-Rasmussen JP, Tewksbury EW, Moss OR, Cesta MF, Wong BA, Bonner JC
Am. J. Respir. Cell Mol. Biol., 2008-09-11;40(3):349-58.
Species: Mouse
Sample Types: BALF
-
CD4+CD25+ regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling.
Authors: Kearley J, Robinson DS, Lloyd CM
J. Allergy Clin. Immunol., 2008-07-30;122(3):617-24.e6.
Species: Mouse
Sample Types: BALF
-
GS143, an IkappaB ubiquitination inhibitor, inhibits allergic airway inflammation in mice.
Authors: Hirose K, Wakashin H, Oki M, Kagami S, Suto A, Ikeda K, Watanabe N, Iwamoto I, Furuichi Y, Nakajima H
Biochem. Biophys. Res. Commun., 2008-07-24;374(3):507-11.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis.
Authors: Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ
J. Immunol., 2008-07-15;181(2):1491-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
Eur. J. Pharmacol., 2008-06-16;590(1):400-8.
Species: Mouse
Sample Types: Tissue Homogenates
-
Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein.
Authors: Johnson TR, Rothenberg ME, Graham BS
J. Leukoc. Biol., 2008-06-02;84(3):748-59.
Species: Mouse
Sample Types: Tissue Homogenates
-
CD43 regulates Th2 differentiation and inflammation.
Authors: Cannon JL, Collins A, Mody PD, Balachandran D, Henriksen KJ, Smith CE, Tong J, Clay BS, Miller SD, Sperling AI
J. Immunol., 2008-06-01;180(11):7385-93.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008-04-10;172(5):1209-21.
Species: Mouse
Sample Types: Tissue Homogenates
-
Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells.
Authors: Jacobsen EA, Ochkur SI, Pero RS, Taranova AG, Protheroe CA, Colbert DC, Lee NA, Lee JJ
J. Exp. Med., 2008-03-03;205(3):699-710.
Species: Mouse
Sample Types: BALF
-
Ecto-5'-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis.
Authors: Peng Z, Fernandez P, Wilder T, Yee H, Chiriboga L, Chan ES, Cronstein BN
FASEB J., 2008-02-08;22(7):2263-72.
Species: Mouse
Sample Types: Tissue Homogenates
-
Adenovirus IL-13-induced airway disease in mice: a corticosteroid-resistant model of severe asthma.
Authors: Therien AG, Bernier V, Weicker S, Tawa P, Falgueyret JP, Mathieu MC, Honsberger J, Pomerleau V, Robichaud A, Stocco R, Dufresne L, Houshyar H, Lafleur J, Ramachandran C, O'Neill GP, Slipetz D, Tan CM
Am. J. Respir. Cell Mol. Biol., 2008-02-07;39(1):26-35.
Species: Mouse
Sample Types: BALF
-
IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
Authors: Zheng T, Liu W, Oh SY, Zhu Z, Hu B, Homer RJ, Cohn L, Grusby MJ, Elias JA
J. Immunol., 2008-01-01;180(1):522-9.
Species: Mouse
Sample Types: BALF
-
The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia.
Authors: Kudlacz E, Conklyn M, Andresen C, Whitney-Pickett C, Changelian P
Eur. J. Pharmacol., 2007-12-28;582(1):154-61.
Species: Mouse
Sample Types: BALF
-
B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma.
Authors: Matsumoto K, Fukuyama S, Eguchi-Tsuda M, Nakano T, Matsumoto T, Matsumura M, Moriwaki A, Kan-o K, Wada Y, Yagita H, Shin T, Pardoll DM, Patcharee R, Azuma M, Nakanishi Y, Inoue H
Biochem. Biophys. Res. Commun., 2007-11-05;365(1):170-5.
Species: Mouse
Sample Types: BALF
-
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.
Authors: Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J, Nakanishi K
J. Immunol., 2007-10-01;179(7):4415-23.
Species: Mouse
Sample Types: Serum
-
Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function.
Authors: Pan PY, Wang GX, Yin B, Ozao J, Ku T, Divino CM, Chen SH
Blood, 2007-09-20;111(1):219-28.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling.
Authors: Denis O, van den Brule S, Heymans J, Havaux X, Rochard C, Huaux F, Huygen K
Immunology, 2007-05-16;122(2):268-78.
Species: Mouse
Sample Types: BALF
-
Airway epithelial STAT3 is required for allergic inflammation in a murine model of asthma.
Authors: Simeone-Penney MC, Severgnini M, Tu P, Homer RJ, Mariani TJ, Cohn L, Simon AR
J. Immunol., 2007-05-15;178(10):6191-9.
Species: Mouse
Sample Types: BALF
-
FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions.
Authors: Daniel C, Sartory NA, Zahn N
Mol. Immunol., 2007-05-01;44(13):3305-16.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia.
Authors: Choo-Wing R, Nedrelow JH, Homer RJ, Elias JA, Bhandari V
Am. J. Physiol. Lung Cell Mol. Physiol., 2007-03-30;293(1):L142-50.
Species: Mouse
Sample Types: Cell Lysates
-
T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways.
Authors: Fujiwara M, Hirose K, Kagami S, Takatori H, Wakashin H, Tamachi T, Watanabe N, Saito Y, Iwamoto I, Nakajima H
J. Allergy Clin. Immunol., 2007-03-01;119(3):662-70.
Species: Mouse
Sample Types: BALF
-
Prolonged inhaled allergen exposure can induce persistent tolerance.
Authors: Van Hove CL, Maes T, Joos GF, Tournoy KG
Am. J. Respir. Cell Mol. Biol., 2007-01-11;36(5):573-84.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation.
Authors: Kitamura K, Takeda K, Koya T, Miyahara N, Kodama T, Dakhama A, Takai T, Hirano A, Tanimoto M, Harada M, Gelfand EW
J. Immunol., 2007-01-01;178(1):480-8.
Species: Mouse
Sample Types: BALF
-
Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness.
Authors: Levy BD, Kohli P, Gotlinger K, Haworth O, Hong S, Kazani S, Israel E, Haley KJ, Serhan CN
J. Immunol., 2007-01-01;178(1):496-502.
Species: Mouse
Sample Types: BALF
-
Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z
J. Allergy Clin. Immunol., 2006-10-23;119(1):123-31.
Species: Mouse
Sample Types: BALF
-
Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma.
Authors: Lee KS, Park SJ, Kim SR, Min KH, Jin SM, Lee HK, Lee YC
J. Immunol., 2006-10-15;177(8):5248-57.
Species: Mouse
Sample Types: BALF
-
Allergic airway inflammation inhibits pulmonary antibacterial host defense.
Authors: Beisswenger C, Kandler K, Hess C, Garn H, Felgentreff K, Wegmann M, Renz H, Vogelmeier C, Bals R
J. Immunol., 2006-08-01;177(3):1833-7.
Species: Mouse
Sample Types: BALF
-
Experimental gastrointestinal allergy enhances pulmonary responses to specific and unrelated allergens.
Authors: Brandt EB, Scribner TA, Akei HS, Rothenberg ME
J. Allergy Clin. Immunol., 2006-08-01;118(2):420-7.
Species: Mouse
Sample Types: BALF
-
Obligatory role for interleukin-13 in obstructive lesion development in airway allografts.
Authors: Lama VN, Harada H, Badri LN, Flint A, Hogaboam CM, McKenzie A, Martinez FJ, Toews GB, Moore BB, Pinsky DJ
Am. J. Pathol., 2006-07-01;169(1):47-60.
Species: Mouse
Sample Types: Tissue Homogenates
-
Persistent effects induced by IL-13 in the lung.
Authors: Fulkerson PC, Fischetti CA, Hassman LM, Nikolaidis NM, Rothenberg ME
Am. J. Respir. Cell Mol. Biol., 2006-04-27;35(3):337-46.
Species: Mouse
Sample Types: BALF
-
Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.
Authors: Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stampfli MR, Jordana M
J. Immunol., 2006-02-15;176(4):2568-80.
Species: Mouse
Sample Types: Serum
-
Intranasal exposure to Stachybotrys chartarum enhances airway inflammation in allergic mice.
Authors: Leino MS, Alenius HT, Fyhrquist-Vanni N, Wolff HJ, Reijula KE, Hintikka EL, Salkinoja-Salonen MS, Haahtela T, Mäkelä MJ
Am. J. Respir. Crit. Care Med., 2005-12-01;173(5):512-8.
Species: Mouse
Sample Types: BALF
-
Intranasal mite allergen induces allergic asthma-like responses in NC/Nga mice.
Authors: Shibamori M, Ogino K, Kambayashi Y, Ishiyama H
Life Sci., 2005-10-17;78(9):987-94.
Species: Mouse
Sample Types: BALF
-
MyD88-dependent induction of allergic Th2 responses to intranasal antigen.
Authors: Piggott DA, Eisenbarth SC, Xu L, Constant SL, Huleatt JW, Herrick CA, Bottomly K
J. Clin. Invest., 2005-02-01;115(2):459-67.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice.
Authors: Duan W, Chan JH, McKay K, Crosby JR, Choo HH, Leung BP, Karras JG, Wong WS
Am. J. Respir. Crit. Care Med., 2004-11-19;171(6):571-8.
Species: Mouse
Sample Types: BALF
-
Vbeta14(+) T cells mediate the vaccine-enhanced disease induced by immunization with respiratory syncytial virus (RSV) G glycoprotein but not with formalin-inactivated RSV.
Authors: Johnson TR, Varga SM, Braciale TJ, Graham BS
J. Virol., 2004-08-01;78(16):8753-60.
Species: Mouse
Sample Types: Tissue Homogenates
-
Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma.
Authors: Virag L, Bai P, Bak I, Pacher P, Mabley JG, Liaudet L, Bakondi E, Gergely P, Kollai M, Szabo C
Med. Sci. Monit., 2004-03-01;10(3):BR77-83.
Species: Mouse
Sample Types: BALF
-
Interleukin-9 induces mucous cell metaplasia independent of inflammation.
Authors: Reader JR, Hyde DM, Schelegle ES, Aldrich MC, Stoddard AM, McLane MP, Levitt RC, Tepper JS
Am. J. Respir. Cell Mol. Biol., 2003-06-01;28(6):664-72.
Species: Mouse
Sample Types: BALF
-
Marked airway eosinophilia prevents development of airway hyper-responsiveness during an allergic response in IL-5 transgenic mice.
Authors: Kobayashi T, Iijima K, Kita H
J. Immunol., 2003-06-01;170(11):5756-63.
Species: Mouse
Sample Types: BALF
-
IL-13 is necessary, not simply sufficient, for epicutaneously induced Th2 responses to soluble protein antigen.
Authors: Herrick CA, Xu L, McKenzie AN, Tigelaar RE, Bottomly K
J. Immunol., 2003-03-01;170(5):2488-95.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dual roles of IL-4 in lung injury and fibrosis.
Authors: Huaux F, Liu T, McGarry B, Ullenbruch M, Phan SH
Proteins containing BRCA1 C-terminal (BRCT) domains play crucial roles in response to and repair of DNA damage. Epithelial cell transforming factor ECT2 is a member of the BRCT protein family, but it, 2003-02-15;170(4):2083-92.
Species: Mouse
Sample Types: Serum
-
MHC class II-associated invariant chain isoforms regulate pulmonary immune responses.
Authors: Ye Q, Finn PW, Sweeney R, Bikoff EK, Riese RJ
J. Immunol., 2003-02-01;170(3):1473-80.
Species: Mouse
Sample Types: BALF
-
Persistence of bronchopulmonary hyper-reactivity and eosinophilic lung inflammation after anti-IL-5 or -IL-13 treatment in allergic BALB/c and IL-4Ralpha knockout mice.
Authors: Proust B, Nahori MA, Ruffie C, Lefort J, Vargaftig BB
Clin. Exp. Allergy, 2003-01-01;33(1):119-31.
Species: Mouse
Sample Types: BALF
-
Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy.
Authors: Drouin SM, Corry DB, Hollman TJ, Kildsgaard J, Wetsel RA
J. Immunol., 2002-11-15;169(10):5926-33.
Species: Mouse
Sample Types: BALF
-
IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.
Authors: Shi ZO, Fischer MJ, De Sanctis GT, Schuyler MR, Tesfaigzi Y
J. Immunol., 2002-05-01;168(9):4764-71.
Species: Mouse
Sample Types: BALF
FAQs
-
Assay Diluent RD1-14 contains visible precipitate. Is this acceptable to use?
A small amount of precipitate is expected and acceptable in Assay Diluent RD1-14. Variability has been observed between vials and diluent lots. It may not fully resolubilize but this will not impact assay performance. It is not recommended to filter the precipitate.
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