Mouse IL-18 R alpha /IL-1 R5 Biotinylated Antibody

Catalog #: BAF856
4 Citations Datasheet / COA / SDS

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BAF856

Product Details

Citations (4)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse IL-18 R alpha /IL-1 R5 Biotinylated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse IL‑18 R alpha /IL‑1 R5 in Western blots. In Western blots, approximately 10% cross‑reactivity with recombinant human IL-18 R is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IL‑18 R alpha /IL‑1 R5
Ser19-Gly326
Accession # Q61098

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse IL‑18 R alpha /IL‑1 R5

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-18 R alpha/IL-1 R5

IL-18 R, also known as IL-18 R alpha, is a member of the IL-1 receptor family and has been designated IL-1 R5.

Long Name

Interleukin 18 Receptor alpha

Entrez Gene IDs

8809 (Human); 16182 (Mouse)

Alternate Names

CD218a; CD218a;CDw218a;IL18R1;IL18RA;IL-18Ralpha;IL-18R-alpha;IL18Ralpha2;IL1RRP;IL-1Rrp;Interleukin-18 receptor 1; IL-1 R5; IL-1 Rrp; IL-18 R alpha; IL-18 R1; IL18R alpha; IL18R1; IL-18Ra

Product Datasheets

Product Datasheet

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Related Research Areas

Citations for Mouse IL-18 R alpha /IL-1 R5 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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Increased cytokine production in IL-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling (SOCS).
Authors: Nold-Petry CA, Nold MF, Nielsen JW, Bustamante A, Zepp JA, Storm KA, Hong JW, Kim SH, Dinarello CA
J. Biol. Chem., 2009-07-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC
Protection of CD8+ T cells from activation-induced cell death by IL-18.
Authors: Li W, Kashiwamura S, Ueda H, Sekiyama A, Okamura H
J. Leukoc. Biol., 2007-03-30;82(1):142-51.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections.
Authors: French AR, Sjolin H, Kim S, Koka R, Yang L, Young DA, Cerboni C, Tomasello E, Ma A, Vivier E, Karre K, Yokoyama WM
J. Immunol., 2006-10-15;177(8):4981-90.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
Distinct modulatory effects of LPS and CpG on IL-18-dependent IFN-gamma synthesis.
Authors: Gould MP, Greene JA, Bhoj V, DeVecchio JL, Heinzel FP
J. Immunol., 2004-02-01;172(3):1754-62.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry