Mouse IL-2 R beta Antibody

Catalog #: MAB589 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB589
MAB589-SP

All IL-2 R beta Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse IL-2 R beta Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse IL-2 R beta in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R beta, rhIL‑2 R alpha, recombinant mouse (rm) IL-2 R gamma, rmIL-21 R, or rhIL-15 R is observed. In Western blots under reducing conditions, approximately 50% cross-reactivity with rhIL-2 R beta is observed.

Source

Monoclonal Rat IgG_2A Clone # 130128

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IL-2 R beta
Ala27-Glu240
Accession # P16297

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse IL‑2 R beta

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-2 R beta

IL-2 R beta is a type I transmembrane protein that associates with IL-2 R alpha and the common gamma chain to form a high affinity heterotrimeric receptor complex for IL-2. IL‑2 R beta and the common gamma chain can also associate with IL-15 R alpha. IL-2 R beta is expressed by T, B, NK cells and monocyte/macrophages.

Long Name

Interleukin 2 Receptor beta

Entrez Gene IDs

3560 (Human); 16185 (Mouse)

Alternate Names

CD122 antigen; CD122; high affinity IL-2 receptor beta subunit; High affinity IL-2 receptor subunit beta; IL-15 R beta; IL-2 R beta; IL-2 receptor subunit beta; IL2R beta; IL-2R subunit beta; IL2RB; IL-2Rb; interleukin 15 receptor, beta; interleukin 2 receptor, beta; interleukin-2 receptor subunit beta; P70-75; p75