Mouse IL1RAPL2 Antibody

Catalog #: MAB3068 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB3068
MAB3068-SP

All IL1RAPL2 Antibodies

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Mouse IL1RAPL2 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse IL1RAPL2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross‑reactivity with recombinant human (rh) IL1RAPL2 is observed and no cross-reactivity with recombinant mouse (rm) IL-1 R1, rmIL-1 R2, rmIL-1 R4, rmIL-1 Rrp2, rmSIGIRR, rhIL-1 R3, rhIL-1 R4, rhIL-1 Rrp2, or rhIL1RAPL1 is observed.

Source

Monoclonal Rat IgG_2A Clone # 320017

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IL1RAPL2
Asn18-Ala358
Accession # Q9ERS6

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse IL1RAPL2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL1RAPL2

Interleukin 1 receptor accessory protein-like 2 (IL1RAPL2), also known as TIGIRR-1 and IL-1 R9, is a member of the IL-1 RI-like family of the IL-1 R/Toll-like receptor superfamily. IL1RAPL2 is a type I transmembrane protein that contains three Ig-like domains in its extracellular region and one intracellular TIR domain. IL1RAPL2 is expressed in the central nervous system, and its deletion is associated with some forms of X-linked mental retardation. An alternately spliced variant lacks the transmembrane and cytoplasmic regions. Within their extracellular domains, mouse IL1RAPL2 shares 99% amino acid sequence identity with human IL1RAPL2.

Long Name

Interleukin 1 Receptor Accessory Protein-like 2

Entrez Gene IDs

26280 (Human); 60367 (Mouse)

Alternate Names

IL-1R10; IL-1R-9; IL1R9IL-1 receptor accessory protein-like 2; IL-1R9IL-1RAPL-2; IL1RAPL2; IL-1RAPL2; IL-1-RAPL-2; IL1RAPL-2IL1RAPL-2-related protein; interleukin 1 receptor 9; interleukin 1 receptor accessory protein-like 2; Three immunoglobulin domain-containing IL-1 receptor-related 1; TIGIRR-1; TIGIRR-1Interleukin-1 receptor 9; X-linked interleukin-1 receptor accessory protein-like 2