Mouse Integrin alpha 7 Alexa Fluor® 647-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB3518R-100UG
R&D Systems Antibodies
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Citations (5)
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Mouse Integrin alpha 7 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Integrin alpha 7 in direct ELISAs. Reactivity with other Integrin alpha 7 isoforms was not tested. In direct ELISAs, no cross-reactivity with recombinant mouse Integrin alpha 2, alpha 3, alpha 4, alpha 5, alpha 9, alpha E, alpha X, recombinant human Integrin alpha L, or alpha 11 is observed.
Source
Monoclonal Rat IgG2b Clone # 334908
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin  alpha 7
Phe34-Pro1036
Accession # NP_032424
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
C2C12 mouse myoblast cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Integrin alpha 7

Integrin alpha 7 is a transmembrane glycoprotein that forms heterodimers with Integrin  beta 1 to bind Laminin 1.

Entrez Gene IDs
3679 (Human); 16404 (Mouse); 81008 (Rat); 102130741 (Cynomolgus Monkey)
Alternate Names
FLJ25220; integrin alpha 7 chain; Integrin alpha 7; integrin alpha-7; integrin, alpha 7; ITGA7

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Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

Citations for Mouse Integrin alpha 7 Alexa Fluor® 647-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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  1. Inhibition of type I PRMTs reforms muscle stem cell identity enhancing their therapeutic capacity
    Authors: Dominici, C;Villarreal, OD;Dort, J;Heckel, E;Wang, YC;Ragoussis, I;Joyal, JS;Dumont, N;Richard, S;
    eLife
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. MuSK-BMP signaling in adult muscle stem cells maintains quiescence and regulates myofiber size
    Authors: Madigan, LA;Jaime, D;Fallon, JR;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Loss of CRY2 promotes regenerative myogenesis by enhancing PAX7 expression and satellite cell proliferation
    Authors: Yingxue Hao, Ting Xue, Song‐Bai Liu, Sha Geng, Xinghong Shi, Panting Qian et al.
    MedComm (2020)
  4. Transcriptional reprogramming of skeletal muscle stem cells by the niche environment
    Authors: Felicia Lazure, Rick Farouni, Korin Sahinyan, Darren M. Blackburn, Aldo Hernández-Corchado, Gabrielle Perron et al.
    Nature Communications
  5. Muscle stem cell polarity requires QKI-mediated alternative splicing of Integrin Alpha-7 (Itga7)
    Authors: Claudia Dominici, Stéphane Richard
    Life Science Alliance

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