Mouse Integrin alpha 3/CD49c PE-conjugated Antibody

Catalog #: FAB2787P
2 Citations Datasheet / COA / SDS

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FAB2787P

Detection of Integrin alpha 3/CD49c in C2C12 Mouse Cell Line by Flow Cytometry.

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Mouse Integrin alpha 3/CD49c PE-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Integrin alpha 3/CD49c in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse (rm) Integrin alpha 2, rmIntegrin alpha 4, rmIntegrin alpha 5, rmIntegrin alpha E, rmIntegrin alpha M, rmIntegrin alpha V and rmIntegrin alpha X is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Integrin alpha 3/CD49c
Phe33-Glu993
Accession # Q62470

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of Integrin alpha 3/CD49c in C2C12 Mouse Cell Line by Flow Cytometry. C2C12 mouse myoblast cell line was stained with Goat Anti-Mouse Integrin a3/CD49c PE-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB2787P, filled histogram) or isotype control antibody (IC108P, open histogram). Staining was performed using our Staining Membrane-associated Proteins protocol.

Flow Cytometry

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Detection of Integrin alpha 3/CD49c in XB2 Mouse Cell Line by Flow Cytometry. XB2 mouse teratoma keratinocyte cell line was stained with Goat Anti-Mouse Integrin a3/CD49c PE-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB2787P, filled histogram) or isotype control antibody (Catalog # IC108P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: Integrin alpha 3/CD49c

Integrin alpha 3, also known as CD49c and VLA-3 alpha, is a type I membrane protein that heterodimerizes with Integrin beta 1. alpha 3 beta 1 is a cell surface adhesion molecule that functions as a receptor for Laminin, Fibronectin, Collagen, Epiligrin, Thrombospondin and Chondroitin Sulfate Proteoglycan 4. The extracellular domain of human and mouse Integrin alpha 3 share approximately 87% amino acid sequence homology.

Entrez Gene IDs

3675 (Human); 16400 (Mouse)

Alternate Names

antigen identified by monoclonal J143; CD49 antigen-like family member C; CD49c antigen; CD49c; FLJ34631; FLJ34704; FRP-2; Galactoprotein B3; GAP-B3; GAPB3CD49C; Integrin alpha 3; integrin alpha-3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); ITGA3; MSK18; VCA-2; very late activation protein 3 receptor, alpha-3 subunit; VL3A; VLA-3 subunit alpha; VLA3a

Product Datasheets

Product Datasheet

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Related Research Areas

Citations for Mouse Integrin alpha 3/CD49c PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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Contributions of the integrin beta1 tail to cell adhesive forces.
Authors: Elloumi-Hannachi I, Garcia J, Shekeran A, Garcia A
Exp Cell Res, 2014-11-25;332(2):212-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
Dendritic cells: In vitro culture in two- and three-dimensional collagen systems and expression of collagen receptors in tumors and atherosclerotic microenvironments.
Authors: Sprague L, Muccioli M, Pate M, Singh M, Xiong C, Ostermann A, Niese B, Li Y, Li Y, Courreges M, Benencia F
Exp Cell Res, 2014-02-22;323(1):7-27.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry