Mouse Integrin  alpha 7 APC-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB3518A
Detection of Integrin  alpha 7 in C2C12 Mouse Cell Line by Flow Cytometry.
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Product Details
Citations (11)
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Mouse Integrin  alpha 7 APC-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Integrin alpha 7 in direct ELISAs. Reactivity with other Integrin alpha 7 isoforms was not tested. In direct ELISAs, no cross-reactivity with recombinant mouse Integrin alpha 2, alpha 3, alpha 4, alpha 5, alpha 9, alpha E, alpha X, recombinant human Integrin alpha L, or alpha 11 is observed.
Source
Monoclonal Rat IgG2B Clone # 334908
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin  alpha 7
Phe34-Pro1036
Accession # NP_032424
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of Integrin a7 antibody in C2C12 Mouse Cell Line antibody by Flow Cytometry. View Larger

Detection of Integrin alpha 7 in C2C12 Mouse Cell Line by Flow Cytometry. C2C12 mouse myoblast cell line was stained with Rat Anti-Mouse Integrin a7 APC-conjugated Monoclonal Antibody (Catalog # FAB3518A, filled histogram) or isotype control antibody (Catalog # IC013A, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: Integrin alpha 7

Integrin alpha 7 is a transmembrane glycoprotein that forms heterodimers with Integrin  beta 1 to bind Laminin 1.

Entrez Gene IDs
3679 (Human); 16404 (Mouse); 81008 (Rat); 102130741 (Cynomolgus Monkey)
Alternate Names
FLJ25220; integrin alpha 7 chain; Integrin alpha 7; integrin alpha-7; integrin, alpha 7; ITGA7

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Citations for Mouse Integrin  alpha 7 APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

11 Citations: Showing 1 - 10
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  1. Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity
    Authors: Ryo Fujita, Seiya Mizuno, Taketaro Sadahiro, Takuto Hayashi, Takehito Sugasawa, Fumihiro Sugiyama et al.
    iScience
  2. Fibroadipogenic Progenitors Regulate the Basal Proliferation of Satellite Cells and Homeostasis of Pharyngeal Muscles via HGF Secretion
    Authors: Eunhye Kim, Fang Wu, Danbi Lim, Christopher Zeuthen, Yiming Zhang, James Allen et al.
    Frontiers in Cell and Developmental Biology
  3. miR-378 influences muscle satellite cells and enhances adipogenic potential of fibro-adipogenic progenitors but does not affect muscle regeneration in the glycerol-induced injury model
    Authors: Mucha, O;Podkalicka, P;?ukowska, M;Po?piech, E;Dulak, J;?oboda, A;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. NRF2 Regulates Viability, Proliferation, Resistance to Oxidative Stress, and Differentiation of Murine Myoblasts and Muscle Satellite Cells
    Authors: I Bronisz-Bu, M Kozakowska, K Pietraszek, M Madej, A Józkowicz, A ?oboda, J Dulak
    Cells, 2022-10-21;11(20):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. Sphingosine Phosphate Lyase Is Upregulated in Duchenne Muscular Dystrophy, and Its Inhibition Early in Life Attenuates Inflammation and Dystrophy in Mdx Mice
    Authors: AS De la Garz, SA Moore, J Zamora-Pin, EP Hoffman, K Mistry, A Kumar, JB Strober, P Zhao, JH Suh, JD Saba
    International Journal of Molecular Sciences, 2022-07-08;23(14):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
    Authors: CE Xirouchaki, Y Jia, MJ McGrath, S Greatorex, M Tran, TL Merry, D Hong, MJ Eramo, SC Broome, JST Woodhead, RF D'souza, J Gallagher, E Salimova, C Huang, RB Schittenhe, J Sadoshima, MJ Watt, CA Mitchell, T Tiganis
    Science Advances, 2021-12-15;7(51):eabl4988.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  7. Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration
    Authors: S Zhou, W Zhang, G Cai, Y Ding, C Wei, S Li, Y Yang, J Qin, D Liu, H Zhang, X Shao, J Wang, H Wang, W Yang, H Wang, S Chen, P Hu, L Sun
    Cell Res., 2020-08-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  8. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis
    Authors: D van de Vle, J Demmers, XX Nguyen, Y Campos, E Machado, I Annunziata, H Hu, E Gomero, X Qiu, A Bongiovann, CA Feghali-Bo, A d'Azzo
    Sci Adv, 2019-07-17;5(7):eaav3270.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  9. Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion.
    Authors: Fu X, Xiao J, Wei Y, Li S, Liu Y, Yin J, Sun K, Sun H, Wang H, Zhang Z, Zhang B, Sheng C, Wang H, Hu P
    Cell Res, 2015-05-15;25(6):655-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  10. Myospheres are composed of two cell types: one that is myogenic and a second that is mesenchymal.
    Authors: Westerman K
    PLoS ONE, 2015-02-23;10(2):e0116956.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  11. Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway.
    Authors: Loh KC, Leong WI, Carlson ME
    PLoS ONE, 2012-05-14;7(5):e37218.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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