Mouse Laminin alpha 1 / beta 1 Antibody Summary
Applications
Skubitz, A.P. et al. (1987) Exp. Cell Res. 173:349. This application was not tested by R&D Systems.
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Laminin alpha 1/ beta 1 in Embryonic Mouse Decidua. Laminin alpha 1/ beta 1 was detected in immersion fixed frozen sections of embryonic mouse decidua (E10.5) using 10 µg/mL Rat Anti-Mouse Laminin alpha 1/ beta 1 Monoclonal Antibody (Catalog # MAB4656) overnight at 4 °C. Tissue was stained with the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
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Laminin alpha 1/ beta 1 in Mouse Kidney, Skin, Intestine, and Skeletal Muscle. Laminin alpha 1/ beta 1 was detected in perfusion fixed frozen sections of mouse kidney glomeruli (panel A), skin (panel B), intestine (panel C), and skeletal muscle (panel D) using Rat Anti-Mouse Laminin alpha 1/ beta 1 Monoclonal Antibody (Catalog # MAB4656) at 10 µg/mL overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces. View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Laminin alpha 1
Laminins are heterotrimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. Through interactions with integrins, dystroglycan, and other receptors, Laminins contribute to cell differentation, cell shape and migration, maintenance of tissue phenotypes, and survival. Laminin-1 is comprised of alpha 1, beta 1, and gamma 1 subunits.
Product Datasheets
Citations for Mouse Laminin alpha 1 / beta 1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
8
Citations: Showing 1 - 8
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Identification of tyrosine brominated extracellular matrix proteins in normal and fibrotic lung tissues
Authors: Cruz, LC;Habibovic, A;Dempsey, B;Massafera, MP;Janssen-Heininger, YMW;Lin, MJ;Hoffman, ET;Weiss, DJ;Huang, SK;van der Vliet, A;Meotti, FC;
Redox biology
Species: Mouse
Sample Types: Whole Tissue
Applications: Immunohistochemistry -
A brain-specific angiogenic mechanism enabled by tip cell specialization
Authors: Schevenels, G;Cabochette, P;America, M;Vandenborne, A;De Grande, L;Guenther, S;He, L;Dieu, M;Christou, B;Vermeersch, M;Germano, RFV;Perez-Morga, D;Renard, P;Martin, M;Vanlandewijck, M;Betsholtz, C;Vanhollebeke, B;
Nature
Species: Mouse, Zebrafish
Sample Types: Cell Lysates, Embryo
Applications: Immunohistochemistry, Western Blot -
CRISPR-Cas9 homology-independent targeted integration of exons 1–19 restores full-length dystrophin in mice
Authors: Anthony A. Stephenson, Stefan Nicolau, Tatyana A. Vetter, Gabrielle P. Dufresne, Emma C. Frair, Jessica E. Sarff et al.
Molecular Therapy - Methods & Clinical Development
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Identification of the niche and mobilization mechanism for tissue-protective multipotential bone marrow ILC progenitors
Authors: Q Liu, JH Lee, HM Kang, CH Kim
Science Advances, 2022-11-23;8(47):eabq1551.
Species: Transgenic Mouse
Sample Types: Whole Tissue
Applications: IHC -
Systemic delivery of an AAV9 exon-skipping vector significantly improves or prevents features of Duchenne muscular dystrophy in the Dup2 mouse
Authors: Nicolas Wein, Tatyana A. Vetter, Adeline Vulin, Tabatha R. Simmons, Emma C. Frair, Adrienne J. Bradley et al.
Molecular Therapy - Methods & Clinical Development
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Pre-clinical dose-escalation studies establish a therapeutic range for U7snRNA-mediated DMD exon 2 skipping
Authors: Tabatha R. Simmons, Tatyana A. Vetter, Nianyuan Huang, Adeline Vulin-Chaffiol, Nicolas Wein, Kevin M. Flanigan
Molecular Therapy - Methods & Clinical Development
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Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition
Authors: Emanuela Pasciuto, Oliver T. Burton, Carlos P. Roca, Vasiliki Lagou, Wenson D. Rajan, Tom Theys et al.
Cell
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Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160
Authors: A Perrin, J Rousseau, JP Tremblay
Mol Ther Nucleic Acids, 2016-12-10;6(0):68-79.
Species: Mouse
Sample Types: Cell Lysates, Whole Cells, Whole Tissue
Applications: ICC, IHC, Western Blot
FAQs
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