Mouse MAGP-1/MFAP2 Antibody Summary
Gln17-Cys183
Accession # P55002
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: MAGP-1/MFAP2
MAGP-1 (Microfibril-associated glycoprotein 1; also MFAP-2) is a 30‑33 kDa member of the MFAP family of proteins. It is secreted by endothelial and smooth muscle cells. MAGP-1 apparently mediates the release of Notch extracellular domain and also likely binds to type IV collagen and contributes to elastin fiber formation. Mature mouse MAGP-1 is 167 amino acids (aa) in length. It contains a transglutamination site at Gln20, a tyrosine sulfation motif (aa 46‑49), two potential O-linked glycosylation sites (Thr56 and Thr76), and a Cys-rich C-terminus that generates intermolecular disulfide bonds. One potential splice variant exists that is strictly intracellular and a second shows a 22 aa substitution for the C-terminal 127 amino acids. Mature mouse MAGP-1 is 94% and 87% aa identical to rat and human MAGP‑1, respectively.
Product Datasheets
Citations for Mouse MAGP-1/MFAP2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 4
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Fibrillin-1 Regulates Arteriole Integrity in the Retina
Authors: F Alonso, L Li, I Fremaux, DP Reinhardt, E Génot
Biomolecules, 2022-09-20;12(10):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Latent-transforming growth factor beta-binding protein-2 (LTBP-2) is required for longevity but not for development of zonular fibers
Authors: Y. Shi, W. Jones, W. Beatty, Q. Tan, R.P. Mecham, H. Kumra et al.
Matrix Biology
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A method for preserving and visualizing the three-dimensional structure of the mouse zonule
Authors: Steven Bassnett
Experimental Eye Research
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Targeted deletion of fibrillin-1 in the mouse eye results in ectopia lentis and other ocular phenotypes associated with Marfan syndrome
Authors: W Jones, J Rodriguez, S Bassnett
Dis Model Mech, 2019-01-25;12(1):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC
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