Mouse Meteorin Biotinylated Antibody

Catalog # Availability Size / Price Qty
BAM34751
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Mouse Meteorin Biotinylated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Meteorin in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse CDNF, recombinant rat (rr) CNTF, or rrGDNF is observed.
Source
Monoclonal Rat IgG2B Clone # 347504
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Meteorin
Gly22-Asp291
Accession # Q8C1Q4
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample

Mouse Meteorin Sandwich Immunoassay

Recommended Concentration
Reagent
ELISA Detection (Matched Antibody Pair)
0.5-2 µg/mL 

Use in combination with:

Capture Reagent: Mouse Meteorin Antibody (Catalog # MAB34752)

Standard: Recombinant Mouse Meteorin Protein (Catalog # 3475-MN)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Meteorin

Meteorin is a 31 kDa, secreted protein that is expressed by undifferentiated neural and glial progenitors, and astrocytes. Its name derives from it ability to generate glial cells with long meteor-like tails. Mouse Meteorin is synthesized as a 291 amino acid (aa) precursor that contains a 270 aa mature region. It contains eight cysteines with no identifiable domains or N-linked glycosylation sites. There is one alternate splice form where the first 164 aa of the precursor are deleted and aa 165 is changed to a Met, possibly to serve in translation initiation. Mature mouse Meteorin is 82% and 77% aa identical to human and bovine Meteorin, respectively.  

Entrez Gene IDs
79006 (Human); 70083 (Mouse); 287151 (Rat)
Alternate Names
C16orf23; c380A1.2; Meteorin; METRN

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