Mouse OSCAR Antibody

Catalog # Availability Size / Price Qty
AF1633
AF1633-SP
Product Details
Citations (3)
FAQs
Supplemental Products
Reviews

Mouse OSCAR Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse OSCAR in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse OSCAR
Asp19-Asn228
Accession # Q8VBT3
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse OSCAR

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: OSCAR

OSCAR is a type I transmembrane protein that may be a bone-specific regulator of osteoclast differentiation. It contains two extracellular Ig-like domains that share homology with mouse PIR (Paired immunoglobulin-like receptor) family proteins and members of the human Leukocyte Receptor Complex (LRC)-encoded proteins.

Long Name
Osteoclast-associated Receptor
Entrez Gene IDs
126014 (Human); 232790 (Mouse)
Alternate Names
hOSCAR; MGC33613; OSCAR; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; PIGR3; PIgR-3; Poly-Ig receptor 3; Polymeric immunoglobulin receptor 3

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Citations for Mouse OSCAR Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. Schistosoma�japonicum cystatin suppresses osteoclastogenesis via manipulating the NF?&kappaB signaling pathway
    Authors: Y Chen, B Wei, P Xu, H Tang, L Yang, Y Wang, Y Fu, X Yang, Y Mao
    Molecular Medicine Reports, 2021-02-12;23(4):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  2. DJ-1 controls bone homeostasis through the regulation of osteoclast differentiation
    Authors: HS Kim, ST Nam, SH Mun, SK Lee, HW Kim, YH Park, B Kim, KJ Won, HR Kim, YM Park, HS Kim, MA Beaven, YM Kim, WS Choi
    Nat Commun, 2017-11-15;8(1):1519.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  3. Inactivation of glycogen synthase kinase-3beta is required for osteoclast differentiation.
    Authors: Jang HD, Shin JH, Park DR, Hong JH, Yoon K, Ko R, Ko CY, Kim HS, Jeong D, Kim N, Lee SY
    J. Biol. Chem., 2011-09-23;286(45):39043-50.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot

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