Mouse Plexin B2 (NP_620088.2) VersaClone cDNA

Catalog #: RDC3316 Datasheet / COA / SDS

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RDC3316

Mouse Plexin B2 (NP_620088.2) VersaClone cDNA

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Mouse Plexin B2 (NP_620088.2) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Mouse

Product Datasheets

Product Datasheet

COA

SDS

Background: Plexin B2

Plexin B2 is a 240 kDa member of the B subfamily, Plexin family of semaphorin receptors. It is expressed by cerebellar granule cells, neuroepithelium and chondrocytes and serves as a receptor for Sema4C. Mature human Plexin B2 is 1819 amino acid (aa) in length. It is a type I transmembrane (TM) glycoprotein that contains an 1178 aa extracellular domain (ECD) plus a 620 aa cytoplasmic region. The ECD contains one semaphorin domain (aa 20 - 466) and three IPT repeats (aa 803 - 1092). The ECD may be cleaved into two subunits, a 170 kDa alpha-chain (aa 20 - 1164) and an 80 kDa TM beta-chain that remain noncovalently-linked. Multiple splice variants may exist. One shows an alternate start site at Met1369, while a second shows a deletion of aa 67 - 638. Over aa 20 - 1160, human Plexin B2 is 82% aa identical to mouse Plexin B2.

Entrez Gene IDs

23654 (Human); 140570 (Mouse); 315217 (Rat)

Alternate Names

MM1; MM1KIAA0315dJ402G11.3; Nbla00445; PLEXB2; Plexin B2; plexin-B2; PLXNB2