Mouse Rae-1 Pan Specific PE-conjugated Antibody Summary
Leu29-Ser227
Accession # Q9JI58
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of Rae‑1 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse Rae-1 Pan Specific PE-conjugated Monoclonal Antibody (Catalog # FAB17582P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Rae-1
Rae-1 alpha, beta, gamma, δ and epsilon comprise a family of closely related (88-95% amino acid identity) GPI-linked cell surface proteins that function as ligands for mouse NKG2D, an activating receptor expressed on NK and T cells. Rae-1 transcripts are expressed in mouse embryos and several tumor cell lines but are absent from most normal adult tissues. Rae-1 protein expression on tumor cell lines has been implicated in in vivo tumor rejection.
Product Datasheets
Citations for Mouse Rae-1 Pan Specific PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
12
Citations: Showing 1 - 10
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Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia
Authors: José A. Casado, Antonio Valeri, Rebeca Sanchez-Domínguez, Paula Vela, Andrea López, Susana Navarro et al.
Journal of Clinical Investigation
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SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
Authors: Chang, YH;Yamamoto, K;Fujino, T;Wang, TW;Sugimoto, E;Zhang, W;Yabushita, T;Suzaki, K;Pietsch, EC;Weir, BA;Crescenzo, R;Cowley, GS;Attar, R;Philippar, U;Wunderlich, M;Mizukawa, B;Zheng, Y;Enomoto, Y;Imai, Y;Kitamura, T;Goyama, S;
Cell reports
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Sphingomyelin-derived nanovesicles for the delivery of the IDO1 inhibitor epacadostat enhance metastatic and post-surgical melanoma immunotherapy
Authors: Wang, Z;Li, W;Jiang, Y;Tran, TB;Cordova, LE;Chung, J;Kim, M;Wondrak, G;Erdrich, J;Lu, J;
Nature communications
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
Authors: GK Griffin, J Wu, A Iracheta-V, JC Patti, J Hsu, T Davis, D Dele-Oni, PP Du, AG Halawi, JJ Ishizuka, SY Kim, S Klaeger, NH Knudsen, BC Miller, TH Nguyen, KE Olander, M Papanastas, S Rachimi, EJ Robitschek, EM Schneider, MD Yeary, MD Zimmer, JD Jaffe, SA Carr, JG Doench, WN Haining, KB Yates, RT Manguso, BE Bernstein
Nature, 2021-05-05;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells
Authors: G Itakura, M Ozaki, N Nagoshi, S Kawabata, Y Nishiyama, K Sugai, T Iida, R Kashiwagi, T Ookubo, K Yastake, K Matsubayas, J Kohyama, A Iwanami, M Matsumoto, M Nakamura, H Okano
Sci Rep, 2017-10-11;7(1):12996.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation.
Authors: Liu Q, Sanai N, Jin W, La Cava A, Van Kaer L, Shi F
Nat Neurosci, 2016-01-11;19(2):243-52.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Proinflammatory Proteins S100A8/S100A9 Activate NK Cells via Interaction with RAGE.
Authors: Narumi K, Miyakawa R, Ueda R, Hashimoto H, Yamamoto Y, Yoshida T, Aoki K
J Immunol, 2015-04-24;194(11):5539-48.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Toll-Like receptor 2 (TLR2) and TLR9 play opposing roles in host innate immunity against Salmonella enterica serovar Typhimurium infection.
Authors: Zhan R, Han Q, Zhang C, Tian Z, Zhang J
Infect Immun, 2015-02-09;83(4):1641-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins.
Authors: Klezovich-Benard M, Corre JP, Jusforgues-Saklani H, Fiole D, Burjek N, Tournier JN, Goossens PL
PLoS Pathog., 2012-01-12;8(1):e1002481.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Murine trophoblast cells induce NK cell interferon-gamma production through KLRK1.
Authors: Carayannopoulos LN, Barks JL, Yokoyama WM
Biol. Reprod., 2010-05-19;83(3):404-14.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
NKG2D receptor signaling enhances cytolytic activity by virus-specific CD8+ T cells: evidence for a protective role in virus-induced encephalitis.
Authors: Walsh KB, Lanier LL, Lane TE
J. Virol., 2007-12-26;82(6):3031-44.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
NKG2D blockade prevents autoimmune diabetes in NOD mice.
Authors: Ogasawara K, Hamerman JA, Ehrlich LR, Bour-Jordan H, Santamaria P, Bluestone JA, Lanier LL
Immunity, 2004-06-01;20(6):757-67.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
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