Mouse Serpin A6 Antibody

Catalog #: MAB4065
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB4065
MAB4065-SP

All Serpin A6 Antibodies

Product Details

Citations (1)

Supplemental Products

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Serpin A6 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Serpin A6 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse Serpin A1, A5, B8, C1, D1, E1, E2, F1, F2, I1, recombinant human Serpin A3, A4, B6, B9, G1, I2, or recombinant rat Serpin A6 is observed.

Source

Monoclonal Rat IgG_2B Clone # 433903

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Serpin A6
Val23-Ala397
Accession # Q06770

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse Serpin A6

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Serpin A6

Serpin A6 (also known as corticosteroid-binding globulin/CBG and Transcortin) is a 50‑60 kDa, secreted glycoprotein member of the serpin family of protease inhibitors. It is produced by hepatocytes and transports > 90% of circulating cortisol. Although Serpin A6 is a serpin family member, it shows no protease inhibition. Mature mouse Serpin A6 is 375 amino acids (aa) in length. Over aa 23‑397, mouse Serpin A6 shares 78% and 57% aa sequence identity with rat and human Serpin A6, respectively.

Entrez Gene IDs

866 (Human); 12401 (Mouse); 299270 (Rat)

Alternate Names

antitrypsin), member 6; CBG; CBGcorticosteroid-binding globulin; corticosteroid binding globulin; member 6; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase; Serpin A6; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin); transcortin

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse Serpin A6 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Regulation of corticosteroid-binding globulin release in murine leydig tumor cell line mLTC-1 by luteinizing hormone and interleukin-6
Authors: Zhang, Y;Liu, L;Yang, C;Xie, W;Wang, J;
Archives of biochemistry and biophysics
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

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