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Mouse TRANCE/RANK L/TNFSF11 ELISA Kit - Quantikine

Catalog #: MTR00
68 Citations 6 Reviews Datasheet / COA / SDS
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MTR00
Mouse TRANCE/TNFSF11/RANK L ELISA Standard Curve
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Citations (68)
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Summary Precision Recovery Linearity Data Examples Product Datasheets Preparation and Storage Background Related Research Areas

Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (50 uL), Serum (25 uL)
Sensitivity
5 pg/mL
Assay Range
31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum)
Specificity
Free natural and recombinant mouse TRANCE
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.Cross-species reactivity not tested.
Interference
Interference observed with 1 or more available related molecules.

Product Summary

The Quantikine Mouse TRANCE Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse TRANCE in cell culture supernates and serum. It contains NS0-expressed recombinant mouse TRANCE and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant mouse TRANCE accurately. Results obtained using natural mouse TRANCE showed dose response curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse TRANCE.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 99 261 830 111 285 886
Standard Deviation 8 6.8 18.3 8.8 17.8 57.8
CV% 8.1 2.6 2.2 7.9 6.2 6.5

Recovery

The recovery of mouse TRANCE spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=6) 99 87-116
Serum (n=6) 93 80-104

Linearity

To assess the linearity of the assay, samples containing and/or spiked with mouse TRANCE were diluted with Calibrator Diluent and assayed.
Mouse TRANCE/TNFSF11/RANK L ELISA Linearity

Scientific Data

N/A Mouse TRANCE/TNFSF11/RANK L ELISA Standard Curve View Larger

Mouse TRANCE/TNFSF11/RANK L ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: TRANCE/TNFSF11/RANK L

TRANCE (TNF-related activation-induced cytokines), also known as RANK Ligand, OPGL, or ODF, is a TNF superfamily ligand produced by osteoblasts, bone marrow stromal cells, and activated T cells. It signals through RANK and is antagonized by the decoy receptor Osteoprotegerin. TRANCE stimulates bone resorption, is required for osteoclast differentiation, and is associated with the development of osteoporosis, vascular calcification, osteopetrosis, and progestin-induced breast cancer. It also mediates body temperature regulation and is essential for the development of a lactating mammary gland.

Long Name:
TNF-related Activation-induced Cytokine
Entrez Gene IDs:
8600 (Human); 21943 (Mouse); 117516 (Rat); 102137946 (Cynomolgus Monkey)
Alternate Names:
CD254 antigen; CD254; ODF; OPGL; OPGLOPTB2; Osteoclast differentiation factor; Osteoprotegerin ligand; RANK L; RANKL; RANKLreceptor activator of nuclear factor kappa B ligand; Receptor activator of nuclear factor kappa-B ligand; sOdf; TNF-related activation-induced cytokine; TNFSF11; TRANCE; TRANCEODFhRANKL2; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand superfamily member 11
&#9888; WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
    3. 50 µL Assay Diluent
  3.   Add 50 µL of Assay Diluent to each well.
    4. 50 µL Standard, Control, or Sample
  4.   Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  5.   Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.
    6. 100 µL Conjugate
  6.   Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate and wash 5 times.
    8. 100 µL Substrate Solution
  8.   Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
    9. 100 µL Stop Solution
  9.   Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

68 Citations: Showing 1 - 10
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  1. Bone metastatic mammary tumor cell-derived extracellular vesicles inhibit osteoblast maturation via JNK signaling
    Authors: Uehara, N;Shibusawa, N;Mikami, Y;Kyumoto-Nakamura, Y;Sonoda, S;Kato, H;Yamaza, T;Kukita, T;
    Archives of biochemistry and biophysics
    Species: Mouse
    Sample Types: Cell Culture Supernates
  2. Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to Pagetic lesion formation
    Authors: Miyagawa, K;Tenshin, H;Mulcrone, PL;Delgado-Calle, J;Subler, MA;Windle, JJ;Chirgwin, JM;Roodman, GD;Kurihara, N;
    JCI insight
    Species: Mouse
    Sample Types: Serum
  3. MRL/MpJ Mice Resist to Age-Related and Long-Term Ovariectomy-Induced Bone Loss: Implications for Bone Regeneration and Repair
    Authors: X Gao, X Sun, H Cheng, JJ Ruzbarsky, M Mullen, M Huard, J Huard
    International Journal of Molecular Sciences, 2023-01-25;24(3):.
    Species: Mouse
    Sample Types: Serum
  4. Increased UHMWPE Particle-Induced Osteolysis in Fetuin-A-Deficient Mice
    Authors: C Polan, C Brenner, M Herten, G Hilken, F Grabellus, HL Meyer, M Burggraf, M Dudda, W Jahnen-Dec, C Wedemeyer, MD Kauther
    Journal of functional biomaterials, 2023-01-04;14(1):.
    Species: Mouse
    Sample Types: Serum
  5. MRL/MpJ Mice Resist to Age-Related and Long-Term Ovariectomy-Induced Bone Loss: Implications for Bone Regeneration and Repair
    Authors: X Gao, X Sun, H Cheng, JJ Ruzbarsky, M Mullen, M Huard, J Huard
    International Journal of Molecular Sciences, 2023;24(3):.
    Species: Mouse
    Sample Types: Serum
  6. Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes
    Authors: JM Kim, YS Yang, J Xie, O Lee, J Kim, J Hong, B Boldyreff, O Filhol, H Chun, MB Greenblatt, G Gao, JH Shim
    Cell Death and Differentiation, 2022-02-15;0(0):.
    Species: Mouse
    Sample Types: Serum
  7. Increased bone resorption by long-term cigarette smoke exposure in animal model
    Authors: JJM Junqueira, JD Lourenço, KR da Silva, V Jorgetti, RP Vieira, AA de Araujo, K De Angelis, AT Correia, LHV Alves, IFLC Tibério, AP Barbosa, FDTQDS Lopes
    Heliyon, 2021-12-10;7(12):e08587.
    Species: Mouse
    Sample Types: Tissue Homogenates
  8. Osteoblast-specific inactivation of p53 results in locally increased bone formation
    Authors: N Liao, T Koehne, J Tuckermann, I Triviai, M Amling, JP David, T Schinke, J Luther
    PLoS ONE, 2021-11-18;16(11):e0249894.
    Species: Mouse
    Sample Types: Serum
  9. Decreased Trabecular Bone Mass in Col22a1-Deficient Mice
    Authors: W Zhao, P Wiedemann, EM Wölfel, M Neven, S Peters, T Imhof, M Koch, B Busse, M Amling, T Schinke, TA Yorgan
    Cells, 2021-11-04;10(11):.
    Species: Mouse
    Sample Types: Serum
  10. Hydroxycoumarin Scopoletin Inhibits Bone Loss through Enhancing Induction of Bone Turnover Markers in a Mouse Model of Type 2 Diabetes
    Authors: EJ Lee, W Na, MK Kang, YH Kim, DY Kim, H Oh, SI Kim, SY Oh, S Park, K Park, YH Kang
    Biomedicines, 2021-06-07;9(6):.
    Species: Mouse
    Sample Types: Plasma
  11. Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo
    Authors: RS MacLeod, MB Meyer, J Xiong, KM Cawley, Y Liu, M Onal, NA Benkusky, JD Thostenson, JW Pike, CA O'Brien
    PLoS ONE, 2021-05-10;16(5):e0250974.
    Species: Mouse, Transgenic Mouse
    Sample Types: Serum
  12. The heparan sulfate proteoglycan Syndecan-1 influences local bone cell communication via the RANKL/OPG axis
    Authors: M Timmen, H Hidding, M Götte, TE Khassawna, D Kronenberg, R Stange
    Sci Rep, 2020-11-25;10(1):20510.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  13. Local Production of Osteoprotegerin by Osteoblasts Suppresses Bone Resorption
    Authors: KM Cawley, NC Bustamante, AG Guha, RS MacLeod, J Xiong, I Gubrij, Y Liu, R Mulkey, M Palmieri, JD Thostenson, JJ Goellner, CA O'Brien
    Cell Rep, 2020-09-08;32(10):108052.
    Species: Mouse
    Sample Types: Serum
  14. Glucose transporter 4 mediates LPS-induced IL-6 production in osteoblasts under high glucose conditions
    Authors: S Kato, N Tanabe, M Nagao, J Sekino, K Tomita, M Sakai, K Abe, N Suzuki, K Ueda
    J Oral Sci, 2020-08-31;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  15. Sclerostin expression in trabecular bone is downregulated by osteoclasts
    Authors: M Koide, T Yamashita, K Murakami, S Uehara, K Nakamura, M Nakamura, M Matsushita, T Ara, H Yasuda, JM Penninger, N Takahashi, N Udagawa, Y Kobayashi
    Sci Rep, 2020-08-13;10(1):13751.
    Species: Mouse
    Sample Types: Serum
  16. Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin
    Authors: T Velletri, Y Huang, Y Wang, Q Li, M Hu, N Xie, Q Yang, X Chen, Q Chen, P Shou, Y Gan, E Candi, AP Margherita, M Agostini, H Yang, G Melino, Y Shi, Y Wang
    Cell Death Differ., 2020-07-21;0(0):.
    Species: Mouse
    Sample Types: Serum
  17. Abaloparatide exhibits greater osteoanabolic response and higher cAMP stimulation and beta-arrestin recruitment than teriparatide
    Authors: K Sahbani, CP Cardozo, WA Bauman, HA Tawfeek
    Physiol Rep, 2019-10-01;7(19):e14225.
    Species: Mouse
    Sample Types: Serum
  18. Deficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase
    Authors: T Heckt, LJ Brylka, M Neven, M Amling, T Schinke
    PLoS ONE, 2019-07-17;14(7):e0219734.
    Species: Mouse
    Sample Types: Serum
  19. Human Enriched Serum Following Hydrolysed Collagen Absorption Modulates Bone Cell Activity: from Bedside to Bench and Vice Versa
    Authors: F Wauquier, A Daneault, H Granel, J Prawitt, V Fabien Sou, J Berger, B Pereira, J Guicheux, GY Rochefort, N Meunier, A Blot, Y Wittrant
    Nutrients, 2019-05-31;11(6):.
    Species: Mouse
    Sample Types: Serum
  20. Influences of donor and host age on human muscle-derived stem cell-mediated bone regeneration
    Authors: X Gao, A Lu, Y Tang, J Schneppend, AB Liebowitz, AC Scibetta, ER Morris, H Cheng, C Huard, S Amra, B Wang, MA Hall, WR Lowe, J Huard
    Stem Cell Res Ther, 2018-11-21;9(1):316.
    Species: Mouse
    Sample Types: Serum
  21. Coupling of bone resorption and formation by RANKL reverse signalling
    Authors: Y Ikebuchi, S Aoki, M Honma, M Hayashi, Y Sugamori, M Khan, Y Kariya, G Kato, Y Tabata, JM Penninger, N Udagawa, K Aoki, H Suzuki
    Nature, 2018-09-05;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  22. Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss
    Authors: J Xiong, K Cawley, M Piemontese, Y Fujiwara, H Zhao, JJ Goellner, CA O'Brien
    Nat Commun, 2018-07-25;9(1):2909.
    Species: Mouse
    Sample Types: Plasma
  23. Loss of RANKL in osteocytes dramatically increases cancellous bone mass in the osteogenesis imperfecta mouse (oim)
    Authors: SM Zimmerman, ME Heard-Lips, M Dimori, JD Thostenson, EM Mannen, CA O'Brien, R Morello
    Bone Rep, 2018-07-02;9(0):61-73.
    Species: Mouse
    Sample Types: Bone Marrow Fluid
  24. New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment
    Authors: LC Cheung, J Tickner, AM Hughes, P Skut, M Howlett, B Foley, J Oommen, JE Wells, B He, S Singh, GA Chua, J Ford, CG Mullighan, RS Kotecha, UR Kees
    Leukemia, 2018-05-08;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  25. Central RANK signalling in NPY neurons alters bone mass in male mice
    Authors: NJ Lee, IM Clarke, RF Enriquez, V Nagy, J Penninger, PA Baldock, H Herzog
    Neuropeptides, 2018-02-15;0(0):.
    Species: Mouse
    Sample Types: Serum
  26. Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss
    Authors: N Yang, B Baban, CM Isales, XM Shi
    PLoS ONE, 2017-08-03;12(8):e0181133.
    Species: Mouse
    Sample Types: Serum
  27. Muramyl Dipeptide, a Shared Structural Motif of Peptidoglycans, Is a Novel Inducer of Bone Formation through Induction of Runx2
    Authors: OJ Park, J Kim, J Yang, CH Yun, SH Han
    J. Bone Miner. Res, 2017-04-27;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  28. Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging
    Authors: HM Davis, R Pacheco-Co, EG Atkinson, LR Brun, AR Gortazar, J Harris, M Hiasa, SA Bolarinwa, T Yoneda, M Ivan, A Bruzzaniti, T Bellido, LI Plotkin
    Aging Cell, 2017-03-19;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  29. Silicon Nitride: A Synthetic Mineral for Vertebrate Biology
    Sci Rep, 2016-08-19;6(0):31717.
    Species: Human
    Sample Types: Cell Culture Supernates
  30. Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-kappaB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts.
    Authors: Kassem A, Henning P, Lundberg P, Souza P, Lindholm C, Lerner U
    J Biol Chem, 2015-06-17;290(33):20147-58.
    Species: Mouse
    Sample Types: Tissue Homogenates
  31. The Proteasome Inhibitor Carfilzomib Suppresses Parathyroid Hormone-induced Osteoclastogenesis through a RANKL-mediated Signaling Pathway.
    Authors: Yang Y, Blair H, Shapiro I, Wang B
    J Biol Chem, 2015-05-15;290(27):16918-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  32. A DNA segment spanning the mouse Tnfsf11 transcription unit and its upstream regulatory domain rescues the pleiotropic biologic phenotype of the RANKL null mouse.
    Authors: Onal M, Bishop K, St John H, Danielson A, Riley E, Piemontese M, Xiong J, Goellner J, O'Brien C, Pike J
    J Bone Miner Res, 2015-05-01;30(5):855-68.
    Species: Mouse
    Sample Types: Serum
  33. 5-Azacytidine-induced protein 2 (AZI2) regulates bone mass by fine-tuning osteoclast survival.
    Authors: Maruyama K, Fukasaka M, Uematsu S, Takeuchi O, Kondo T, Saitoh T, Martino M, Akira S
    J Biol Chem, 2015-02-17;290(15):9377-86.
    Species: Mouse
    Sample Types: Serum
  34. Aconitum pseudo-laeve var. erectum inhibits receptor activator of nuclear factor kappa-B ligand-induced osteoclastogenesis via the c-Fos/nuclear factor of activated T-cells, cytoplasmic 1 signaling pathway and prevents lipopolysaccharide-induced bone loss in mice.
    Authors: Baek, Jong Min, Kim, Ju-Young, Cheon, Yoon-Hee, Park, Sun-Hyan, Ahn, Sung-Jun, Yoon, Kwon-Ha, Oh, Jaemin, Lee, Myeung S
    Molecules, 2014-08-05;19(8):11628-44.
    Species: Mouse
    Sample Types: Serum
  35. Inhibition of bone remodeling in young mice by bisphosphonate displaces the plasma cell niche into the spleen.
    Authors: Teufel S, Grotsch B, Luther J, Derer A, Schinke T, Amling M, Schett G, Mielenz D, David J
    J Immunol, 2014-06-04;193(1):223-33.
    Species: Mouse
    Sample Types: Serum
  36. Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL.
    Authors: Ohba T, Cole H, Cates J, Slosky D, Haro H, Ando T, Schwartz H, Schoenecker J
    J Bone Miner Res, 2014-06-01;29(6):1431-45.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  37. Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone.
    Authors: Teramachi J, Zhou H, Subler M, Kitagawa Y, Galson D, Dempster D, Windle J, Kurihara N, Roodman G
    J Bone Miner Res, 2014-06-01;29(6):1456-65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  38. Effects of neuropeptides and mechanical loading on bone cell resorption in vitro.
    Authors: Yoo Y, Kwag J, Kim K, Kim C
    Int J Mol Sci, 2014-04-08;15(4):5874-83.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  39. Effects of the peroxisome proliferator-activated receptor (PPAR)-delta agonist GW501516 on bone and muscle in ovariectomized rats.
    Authors: Mosti M, Stunes A, Ericsson M, Pullisaar H, Reseland J, Shabestari M, Eriksen E, Syversen U
    Endocrinology, 2014-04-07;155(6):2178-89.
    Species: Rat
    Sample Types: Plasma
  40. Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis.
    Authors: Gruenwald K, Castagnola P, Besio R, Dimori M, Chen Y, Akel N, Swain F, Skinner R, Eyre D, Gaddy D, Suva L, Morello R
    J Bone Miner Res, 2014-03-01;29(3):666-75.
    Species: Mouse
    Sample Types: Serum
  41. Autophagy in osteoblasts is involved in mineralization and bone homeostasis.
    Authors: Nollet M, Santucci-Darmanin S, Breuil V, Al-Sahlanee R, Cros C, Topi M, Momier D, Samson M, Pagnotta S, Cailleteau L, Battaglia S, Farlay D, Dacquin R, Barois N, Jurdic P, Boivin G, Heymann D, Lafont F, Lu S, Dempster D, Carle G, Pierrefite-Carle V
    Autophagy, 2014-01-01;10(11):1965-77.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  42. Resolvin E1 and chemokine-like receptor 1 mediate bone preservation.
    Authors: Gao L, Faibish D, Fredman G, Herrera B, Chiang N, Serhan C, Van Dyke T, Gyurko R
    J Immunol, 2012-12-14;190(2):689-94.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  43. Soluble rank ligand produced by myeloma cells causes generalised bone loss in multiple myeloma.
    Authors: Buckle, Clive He, De Leenheer, Evy, Lawson, Michelle, Yong, Kwee, Rabin, Neil, Perry, Mark, Vanderkerken, Karen, Croucher, Peter Ia
    PLoS ONE, 2012-08-29;7(8):e41127.
    Species: Mouse
    Sample Types: Serum
  44. Receptor activator of nuclear factor kappaB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss.
    Authors: Onal M, Xiong J, Chen X, Thostenson J, Almeida M, Manolagas S
    Oncogene, 2012-07-10;287(35):29851-60.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  45. Osteoprotection by semaphorin 3A.
    Authors: Hayashi M, Nakashima T, Taniguchi M, Kodama T, Kumanogoh A, Takayanagi H
    Nature, 2012-05-03;485(7396):69-74.
    Species: Mouse
    Sample Types: Serum
  46. Strontium fructose 1,6-diphosphate prevents bone loss in a rat model of postmenopausal osteoporosis via the OPG/RANKL/RANK pathway.
    Authors: Ma B, Zhang Q, Wu D, Wang YL, Hu YY, Cheng YP, Yang ZD, Zheng YY, Ying HJ
    Acta Pharmacol. Sin., 2012-03-19;33(4):479-89.
    Species: Rat
    Sample Types: Serum
  47. The RANKL distal control region is required for the increase in RANKL expression, but not the bone loss, associated with hyperparathyroidism or lactation in adult mice.
    Authors: Onal M, Galli C, Fu Q, Xiong J, Weinstein RS, Manolagas SC, O'Brien CA
    Mol. Endocrinol., 2011-12-29;26(2):341-8.
    Species: Mouse
    Sample Types: Plasma
  48. Mechanisms inducing low bone density in duchenne muscular dystrophy in mice and humans.
    Authors: Rufo A, Del Fattore A, Capulli M, Carvello F, De Pasquale L, Ferrari S, Pierroz D, Morandi L, De Simone M, Rucci N, Bertini E, Bianchi ML, De Benedetti F, Teti A
    J. Bone Miner. Res., 2011-08-01;26(8):1891-903.
    Species: Mouse
    Sample Types: Serum
  49. C17 prevents inflammatory arthritis and associated joint destruction in mice.
    Authors: Chao C, Joyce-Shaikh B, Grein J
    PLoS ONE, 2011-07-25;6(7):e22256.
    Species: Mouse
    Sample Types: Serum
  50. Effects of relaxin and estrogens on bone remodeling markers, receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG), in rat adjuvant-induced arthritis.
    Authors: Ho TY, Santora K, Chen JC, Frankshun AL, Bagnell CA
    Bone, 2011-03-16;48(6):1346-53.
    Species: Rat
    Sample Types: Plasma
  51. Functional characterization of a novel mutation localized in the start codon of the tissue-nonspecific alkaline phosphatase gene.
    Authors: Mentrup B, Marschall C, Barvencik F, Amling M, Plendl H, Jakob F, Beck C
    Bone, 2011-03-16;48(6):1401-8.
    Species: Rat
    Sample Types: Plasma
  52. Systemic effects of ulna loading in male rats during functional adaptation.
    Authors: Sample SJ, Collins RJ, Wilson AP, Racette MA, Behan M, Markel MD, Kalscheur VL, Hao Z, Muir P
    J. Bone Miner. Res., 2010-09-01;25(9):2016-28.
    Species: Rat
    Sample Types: Plasma
  53. Increased trabecular bone formation in mice lacking the growth factor midkine.
    Authors: Neunaber C, Catala-Lehnen P, Beil FT
    J. Bone Miner. Res., 2010-08-01;25(8):1724-35.
    Species: Mouse
    Sample Types: Serum
  54. ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency.
    Authors: Sauer AV, Mrak E, Hernandez RJ, Zacchi E, Cavani F, Casiraghi M, Grunebaum E, Roifman CM, Cervi MC, Ambrosi A, Carlucci F, Roncarolo MG, Villa A, Rubinacci A, Aiuti A
    Blood, 2009-07-24;114(15):3216-26.
    Species: Mouse
    Sample Types: Serum
  55. Mecp2 deficiency decreases bone formation and reduces bone volume in a rodent model of Rett syndrome.
    Authors: O'Connor RD, Zayzafoon M, Farach-Carson MC, Schanen NC
    Bone, 2009-05-03;45(2):346-56.
    Species: Mouse
    Sample Types: Serum
  56. Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice.
    Authors: Pierroz DD, Rufo A, Bianchi EN, Glatt V, Capulli M, Rucci N, Cavat F, Rizzoli R, Teti A, Bouxsein ML, Ferrari SL
    J. Bone Miner. Res., 2009-05-01;24(5):775-84.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  57. Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro.
    Authors: Wang L, Zhao R, Shi X, Wei T, Halloran BP, Clark DJ, Jacobs CR, Kingery WS
    Bone, 2009-04-18;45(2):309-20.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  58. Overexpression of bone sialoprotein leads to an uncoupling of bone formation and bone resorption in mice.
    Authors: Valverde P, Zhang J, Fix A, Zhu J, Ma W, Tu Q, Chen J
    J. Bone Miner. Res., 2008-11-01;23(11):1775-88.
    Species: Mouse
    Sample Types: Serum
  59. Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma.
    Authors: Qiang YW, Chen Y, Stephens O, Brown N, Chen B, Epstein J, Barlogie B, Shaughnessy JD
    Blood, 2008-02-27;112(1):196-207.
    Species: Human, Mouse
    Sample Types: Cell Culture Supernates
  60. Comparison of the effects of genistein and zoledronic acid on the bone loss in OPG-deficient mice.
    Authors: Liu J, Xu K, Wen G, Guo H, Li S, Wu X, Dai R, Sheng Z, Liao E
    Bone, 2008-02-08;42(5):950-9.
    Species: Mouse
    Sample Types: Serum
  61. The essential role of IFN-gamma in the control of lethal Aggregatibacter actinomycetemcomitans infection in mice.
    Authors: Garlet GP, Cardoso CR, Campanelli AP, Garlet TP, Avila-Campos MJ, Cunha FQ, Silva JS
    Microbes Infect., 2008-01-25;10(5):489-96.
    Species: Mouse
    Sample Types: Tissue Homogenates
  62. Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice.
    Authors: Morony S, Tintut Y, Zhang Z, Cattley RC, Van G, Dwyer D, Stolina M, Kostenuik PJ, Demer LL
    Circulation, 2008-01-02;117(3):411-20.
    Species: Mouse
    Sample Types: Plasma
  63. Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction.
    Authors: Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, Toyama Y, Tada N
    J. Immunol., 2007-07-01;179(1):639-46.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  64. Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression.
    Authors: Brechter AB, Lerner UH
    Arthritis Rheum., 2007-03-01;56(3):910-23.
    Species: Mouse
    Sample Types: Whole Tissue
  65. B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo.
    Authors: Li Y, Toraldo G, Li A, Yang X, Zhang H, Qian WP, Weitzmann MN
    Blood, 2007-01-03;109(9):3839-48.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  66. Osteoprotegerin reduces the serum level of receptor activator of NF-kappaB ligand derived from osteoblasts.
    Authors: Nakamichi Y, Udagawa N, Kobayashi Y, Nakamura M, Yamamoto Y, Yamashita T, Mizoguchi T, Sato M, Mogi M, Penninger JM, Takahashi N
    J. Immunol., 2007-01-01;178(1):192-200.
    Species: Mouse
    Sample Types: Serum
  67. Attenuation of bone mass and increase of osteoclast formation in decoy receptor 3 transgenic mice.
    Authors: Tang CH, Hsu TL, Lin WW, Lai MZ, Yang RS, Hsieh SL, Fu WM
    J. Biol. Chem., 2006-11-10;282(4):2346-54.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  68. New 19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 analogs strongly stimulate osteoclast formation both in vivo and in vitro.
    Authors: Sato M, Nakamichi Y, Nakamura M, Sato N, Ninomiya T, Muto A, Nakamura H, Ozawa H, Iwasaki Y, Kobayashi E, Shimizu M, DeLuca HF, Takahashi N, Udagawa N
    Bone, 2006-10-25;40(2):293-304.
    Species: Mouse
    Sample Types: Serum

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Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit
By Mary-Kate Hayward on 04/05/2024
Sample Tested: Mammary gland tissue

Performed using normal mouse mammary tissue lysates.

Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit
By Anonymous on 10/21/2021
Sample Tested: Serum
Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit MTR00
Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit
By Anonymous on 04/12/2018
Sample Tested: ?TC-6 mouse beta cell insulinoma cell line
Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit
By Anonymous on 04/10/2018
Sample Tested: 7TD1 mouse hybridoma cell line
Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit
By Anonymous on 03/25/2018
Sample Tested: 4T1.2 mouse mammary carcinoma cells
Mouse TRANCE/RANK L/TNFSF11 Quantikine ELISA Kit
By Anonymous on 03/25/2018
Sample Tested: Cell culture supernatant