Mouse TRIM5 Antibody

Catalog #: AF3550
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3550
AF3550-SP

All TRIM5 Antibodies

Product Details

Citations (1)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse TRIM5 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse TRIM5 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human TRIM5 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse TRIM5
Ala2-Gln249
Accession # AAH38937

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse TRIM5

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TRIM5

TRIM5 belongs to the large family of TRIM proteins, which are also named RBCC proteins. These proteins contain a RING domain, one or two B-boxes (CHC3H2 zinc finger motifs), and the coiled-coil domain. Different TRIM proteins contain C-terminals that vary in length and composition. They also have different functions and cellular localization. TRIM5 possesses a B30.2 (also known as RFP-like or PRY-SPRY) C-terminal domain and exists as homotrimers. TRIM5 is a single protein RING finger E3 ubiquitin ligase and has been shown to have antiretroviral activities. Mouse TRIM5 shares 49% and 81% amino acid sequence homology with human and rat TRIM5, respectively.

Long Name

Tripartite Motif-containing 5

Entrez Gene IDs

85363 (Human)

Alternate Names

EC 6.3.2; EC 6.3.2.-; RING finger protein 88; RNF88; RNF88tripartite motif protein TRIM; TRIM5; TRIM5alpha; tripartite motif containing 5; tripartite motif protein TRIM5; tripartite motif-containing 5; tripartite motif-containing protein 5

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse TRIM5 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Tripartite Motif (TRIM) 12c, a Mouse Homolog of TRIM5, Is a Ubiquitin Ligase That Stimulates Type I IFN and NF-kB Pathways along with TNFR-Associated Factor 6.
Authors: Chang TH, Yoshimi R, Ozato K.
J. Immunol.

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Reviews for Mouse TRIM5 Antibody

There are currently no reviews for this product. Be the first to review Mouse TRIM5 Antibody and earn rewards!

Have you used Mouse TRIM5 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review