Mouse UGRP1/SCGB3A2 Antibody

Catalog # Availability Size / Price Qty
MAB3465
MAB3465-SP
Product Details
Citations (4)
FAQs
Supplemental Products
Reviews

Mouse UGRP1/SCGB3A2 Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse UGRP1/SCGB3A2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human UGRP1 is observed.
Source
Monoclonal Rat IgG2B Clone # 381707
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant mouse UGRP1/SCGB3A2 isoform C
Leu22-Leu139
Accession # Q920H1
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Mouse UGRP1/SCGB3A2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: UGRP1/SCGB3A2

UGRP1 (also secretglobin gene family 3A2/SCGB3A2) is an 18 kDa, secreted nonglycosylated polypeptide that is a member of the Uteroglonin family, UGRP subfamily. Mouse UGRP1(isoform A) circulates as a 37 kDa homodimer. Its mature form is 70 amino acids in length. There are two large alternate splice forms termed B and C. UGRP1B is a secreted homodimer that shows a 22 aa insert between aa 84 and 85 of the short form. UGRP1C contains a 55 aa substitution for the C-terminal seven aa of the short form, predicting a 118 aa secreted form. The common portion of mature mouse UGRP1 (isoforms A, B and C) shares 86% and 81% aa identity with rat and human UGRP1, respectively.

Long Name
Uteroglobin-related Protein 1
Entrez Gene IDs
117156 (Human); 117158 (Mouse)
Alternate Names
LU103; Pneumo secretory protein 1; PnSP-1; PNSP1secretoglobin family 3A member 2; SCGB3A2; secretoglobin, family 3A, member 2; UGRP1; UGRP1pnSP-1; Uteroglobin-related protein 1

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Citations for Mouse UGRP1/SCGB3A2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function
    Authors: He, H;Bell, SM;Davis, AK;Zhao, S;Sridharan, A;Na, CL;Guo, M;Xu, Y;Snowball, J;Swarr, DT;Zacharias, WJ;Whitsett, JA;
    Nature communications
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  2. Airway basal cells show regionally distinct potential to undergo metaplastic differentiation
    Authors: Yizhuo Zhou, Ying Yang, Lihao Guo, Jun Qian, Jian Ge, Debora Sinner et al.
    eLife
  3. Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.
    Authors: Carlos S, Helu L, Jun Q et al.
    iScience.
  4. An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea
    Authors: Yin W, Liontos A, Koepke J et al.
    bioRxiv

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