MRS 2690
Chemical Name: Diphosphoric acid 1-α-D-glucopyranosyl ester 2-[(4'-methylthio)uridin-5''-yl] ester disodium salt
Purity: ≥98%
Biological Activity
MRS 2690 is a potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.This product is typically reconstituted in water.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor.
Ko et al.
J.Med.Chem., 2007;50:2030
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Citation for MRS 2690
The citations listed below are publications that use Tocris products. Selected citations for MRS 2690 include:
1 Citation: Showing 1 - 1
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The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells.
Authors: Gao Et al.
Neuropsychopharmacology 2013;9:31
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