MRS 2905
Chemical Name: 2-Thiouridine-5'-O-(α, β-methylene)diphosphate trisodium salt
Purity: ≥98%
Biological Activity
MRS 2905 is a potent and selective P2Y14 receptor agonist (EC50 = 0.92 nM). Exhibits >2000-fold selectivity over P2Y6.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups
Das et al.
J.Med.Chem., 2010;53:471 -
UDP-sugars as extracellular signaling molecules: cellular and physiologic consequences of P2Y14 receptor activation.
Lazarowski et al.
Mol.Pharmacol., 2015;88:151
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