MRS 3777 hemioxalate
Discontinued Product
Chemical Name: 2-Phenoxy-6-(cyclohexylamino)purine hemioxalate
Purity: ≥98%
Biological Activity
High affinity adenosine A3 receptor antagonist (Ki = 47 nM) that displays > 200-fold selectivity versus A1, A2A and A2B receptors.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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"Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists.
Perreira et al.
J.Med.Chem., 2005;48:4910 -
Adenosine receptors as therapeutic targets.
Jacobson and Gao
Nat.Rev.Drug Discov., 2006;5:247 -
Progress in the pursuit of therapeutic adenosine receptor antagonists.
Moro et al.
Med.Res.Rev., 2006;26:131
Product Datasheets
Citation for MRS 3777 hemioxalate
The citations listed below are publications that use Tocris products. Selected citations for MRS 3777 hemioxalate include:
1 Citation: Showing 1 - 1
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Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells.
Authors: Schneider Et al.
Nature 2015;14:201
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