N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide
Chemical Name: N-Acetyl-O-phosphono-L-tyrosyl-N,N-dipentyl-L-α-glutamine
Biological Activity
N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide is a phosphopeptide; binds to the src SH2 domain.Technical Data
(Modifications: Tyr-1 = N-Ac-p-Tyr, Glu-2 = Glu-dipentylamide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
Charifson et al.
Biochemistry, 1997;36:6283 -
Potent dipeptide inhibitors of the pp60c-src SH2 domain.
Pacofsky et al.
J.Med.Chem., 1998;41:1894
Product Datasheets
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