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N-Acetylpuromycin

Catalog #: 5679
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5679/10
N-Acetylpuromycin | CAS No. 22852-13-7 | Additional TGF-beta Receptor Products
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Description: Downregulates SnoN and Ski protein expression; promotes TGF-β signaling

Chemical Name: 3'-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine

Purity: ≥98%

Product Details
Citations (2)
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Biological Activity

N-Acetylpuromycin downregulates SnoN and Ski protein expression; promotes TGF-β signaling, independently of MAPK activation. Does not bind ribosomes or block protein synthesis.

Technical Data

M.Wt:
513.55
Formula:
C24H31N7O6
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
22852-13-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for N-Acetylpuromycin

The citations listed below are publications that use Tocris products. Selected citations for N-Acetylpuromycin include:

2 Citations: Showing 1 - 2

  1. A Semiautomated, Phenotypic, In Vitro Scratch Assay for Assessing Retinal Pigment Epithelial Cell Wound Healing.
    Authors: Alun R Et al.
    J Ocul Pharmacol Ther  2020;36:257-266
  2. Directed differentiation of regulatory T cells from naive T cells and prevention of their inflammation-mediated instability using small molecules.
    Authors: Hossein Et al.
    Clin Exp Immunol  2020;201:205-221

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