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N-Methylquipazine dimaleate

Catalog #: 0566 Datasheet / COA / SDS

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N-Methylquipazine dimaleate | CAS No. 171205-17-7 | 5-HT3 Receptor Agonists
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Description: 5-HT3 agonist

Chemical Name: 2-(1-N-Methylpiperazinyl)quinoline dimaleate

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Biological Activity

N-Methylquipazine dimaleate is a 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites.

Technical Data

M.Wt:
459.45
Formula:
C14H17N3.(C4H4O4)2
Solubility:
Soluble to 50 mM in water
Storage:
Store at RT
CAS No:
171205-17-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study.
    Glennon et al.
    Eur.J.Pharmacol., 1989;168:387

Product Datasheets

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